13,411 research outputs found

    Association between the Glu298Asp and T(-786)C polymorphisms of the endothelial nitric oxide synthase gene and respiratory distress in preterm neonates

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    Sivash E, Babaoglu M, Yasar U, Yurdakok M, Bozkurt A, Korkmaz A, Yigit Tekinalp G. Association between the Glu298Asp and T(-786)C polymorphisms of the endothelial nitric oxide synthase gene and respiratory distress in preterm neonates. Turk J Pediatr 2010; 52: 145-149

    Energy dissipation and flux laws for unsteady turbulence

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    Direct Numerical Simulations of spatially periodic unsteady turbulence show that the high Reynolds number scalings of the instantaneous energy dissipation rate and interscale energy flux at intermediate wavenumbers are qualitatively different from the well-known u(t)3/L(t)u'(t)^{3}/L(t) cornerstone scalings of equilibrium turbulence where u(t)u'(t) and L(t)L(t) are time-dependent rms velocity and integral length-scales. Instead, they both scale as U0L0u(t)2/L(t)2U_{0}L_{0}\:u'(t)^2/L(t)^2 where L0L_0 and U0U_0 are length and velocity scales characterizing initial/overall unsteady turbulence conditions

    Sweeping has no effect on renormalized turbulent viscosity

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    We perform renormalization group analysis (RG) of the Navier-Stokes equation in the presence of constant mean velocity field U0\mathbf U_0, and show that the renormalized viscosity is unaffected by U0\mathbf U_0, thus negating the ``sweeping effect", proposed by Kraichnan [Phys. Fluids {\bf 7}, 1723 (1964)] using random Galilean invariance. Using direct numerical simulation, we show that the correlation functions u(k,t)u(k,t+τ)\langle {\mathbf u} ({\mathbf k}, t){\mathbf u}({\mathbf k}, t+\tau) \rangle for U0=0\mathbf U_0 =0 and U00\mathbf U_0 \ne 0 differ from each other, but the renormalized viscosity for the two cases are the same. Our numerical results are consistent with the RG calculations

    Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

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    IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells

    Spatially-localized time dependent solutions including turbulence and their interactions in 2D Kolmogorov flow

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    In 2D Kolmogorov flow in small aspect ratio domains, spatially-localized solutions such as kink, traveling or time-dependent kink-antikink pars coexist. However, the conservation of the flow rate in the y direction strongly restrict combination of localized solutions and their positioning. We find that by adding a homogeneous flow U y their positioning is controlled and each of localized solutions including a spatially-localized chaos is isolated. Numerical results suggest that these isolated solutions can be elements constructing a whole flow

    Mean Flow generation due to longitudinal librations of side-walls of a rotating annulus

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    Laboratory experiments with rotating annuli are reported that reveal a prograde jet, which is adjacent either to a (longitudinally) librating inner straight cylinder or to a librating inner truncated cone (frustum), whereas the outer cylindrical wall and bottom and top lids rotate with constant angular velocity. In the frustum case, the jet is located on a straight cylindrical surface which is circumscribed about the frustum and joins the bottom lid. These findings are supported by direct numerical simulations which show good agreement between experimental data and numerical results and, when the centrifugal instability of the Stokes boundary layer near the oscillating sidewall does not set in, highlight the important role of local dynamical processes in the corners, between the inner cylinder and the lids, in producing the prograde jet

    DNS of inertial wave attractors in a librating annulus with height-dependent gap width

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    Direct numerical simulations (DNS) of inertial wave attractors have been carried out in a librating Taylor-Couette system with broken mirror symmetry in the radial-axial cross-section. The inertial wave excitation mechanism and its localisation at the edges was clarified by applying boundary layer theory. Additional resonance peaks in the simulated response spectra were found to agree with low-order wave attractors obtained by geometric ray tracing. Numerics and theory are in qualitative agreement with recent lab experiments

    Taylor-Couette flow with asymmetric end-walls boundary conditions

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    In the paper the authors present the results obtained during a numerical (Direct Numerical Simulation/Spectral Vanishing Viscosity method - DNS/SVV) and experimental investigations (Kalliroscope, PIV) of the Taylor-Couette flow with asymmetric boundary conditions. In the paper attention is focused on the laminar-turbulent transition process. The main purpose of the research is to investigate the influence of different parameters (aspect ratio, curvature parameter, end-walls boundary conditions) on the flow structure and on the flow characteristics. The transverse current Jω is computed from the velocity field obtained numerically. The λ2 criterion has been used for numerical visualization

    Wave turbulence of a rotating array of quantized vortices in the T → 0 temperature limit

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    The dynamics of quantized vortices in the zero temperature limit T0T \rightarrow 0 is currently of great interest, particularly in the case of the Fermi superfluid 3^3He-B. Here we study wave turbulence, generated by the librating motion of a rotating cylindrical container filled with 3^3He-B, in the limit of vanishing viscous forces at temperatures T0.2TcT \leq 0.2 T_{c}. The polarization of the quantized vortices with respect to the axis of rotation is measured using non-invasive NMR techniques. We observe a decrease of the polarization when the librating motion is started, and a two-stage relaxation process when the modulation of the rotation velocity is stopped. The first relaxation process is associated with the dissipation of large-scale flow stored in inertial waves and the solid body rotation of the vortex array. From the decay of these energy reservoirs we determine the rate of energy dissipation of large-scale flow. The later second process is related to the relaxation of Kelvin waves on individual vortices. This process is monitored by the recovery of the polarization. The existence of a Kelvin wave cascade at the lowest temperatures is currently a central open question. We supply some evidence for the cascade

    University of Texas at Arlington (U. T. A.) President Spaniolo with author Jeffrey Toobin

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    University of Texas at Arlington (U. T. A.) President Spaniolo with author Jeffrey Toobin, legal analyst for The New Yorker, 03/2010https://mavmatrix.uta.edu/specialcollections_spaniolomaterials/1038/thumbnail.jp
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