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    A study on an experimental infection of sheep with Mycoplasma agalactiae

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    The results of an experimental infection of sheep with a field strain of Mycoplasma agalactiae are reported. Six sheep, seronegative to M. agalactiae were used: three sheep were inoculated by the conjunctival route (group A) and three sheep intranasally (group B). The clinical signs were observed 20 days after infection but the shedding of Mycoplasma agalactiae, particularly from the nasal route and with milk, started a few days post infection (d.p.i.) (1st d.p.i. and 9th d.p.i. respectively). Antibody titers were first detected after 28 d.p.i. in group B and after 35 d.p.i. in group A

    Paratuberculosis at European scale: an overview from 2010 to 2017

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    Mycobacterium avium subsp. paratuberculosis (MAP) is the etiological agent of paratuberculosis (PTB), a disease affecting domestic and wild ruminants. MAP may also play a zoonotic role in Crohn's disease. Although both governments and industries are carrying out programmes to prevent and control the infection, there is a lack of harmonization across Europe. Moreover, the success of these programmes is influenced by the current lack of sensitivity of the diagnostic tests used. For these reasons, it is complex to evaluate the overall epidemiological situation of this disease. This study describes the European distribution of PTB from 2010 to 2017 using the information reported by Member Countries to the OIE. Countries were classified in three categories ('Absent', 'Epizootic', 'Enzootic') depending on the disease epidemiology, and the trend of countries reporting the disease presence was computed throughout the study period. A multilevel model with random slope was built for twelve countries, with complete reporting history. Most of the countries (57.44%) were classified as 'Enzootic'. The percentage of countries reporting the disease presence slightly increased along the study period, probably due to the improvement of PTB monitoring, rather than to a deterioration of the epidemiological situation of the disease in Europe. Results of the model account for different dynamics in the number of outbreaks reported by 'Enzootic' and 'Epizootic' countries
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