1,721,041 research outputs found
ECHO DOPPLER DUPLEX SCANNER AND COLOR IN THE STUDY OF PORTAL-HYPERTENSION
No full textIn the present state of the art, the Doppler duplex scanner provides much information about portal hypertension and its associated pathology, liver cirrhosis, hepatic malformations, vascular or avascular structures, hepatic transplants, and ascites. Its usefulness for experimental studies, providing new insight into the pathophysiology of this disease, has been proven. It is limited by the subjectivity of the conclusions, and by its poor feasibility in fat patients and those with excessive abdominal gas. However, the noninvasive nature of Doppler and its relative low cost make it a useful first step in the evaluation of portal hypertension
Innovation in a traditional setting in Italy: a course on cerebral and peripheral arteriopathy diagnosis for family physicians.
No full textOxidation of circulating proteins in alcoholics: Role of acetaldehyde and xanthine oxidase
No full textBackground/Aims: This study aimed to evaluate the protein and lipid redox status in plasma, erythrocytes and erythrocyte ghosts of alcoholics and of patients with non-alcoholic liver disease; we also investigated the relation to glutathione levels and the role of acetaldehyde and xanthine oxidase activity in plasma. Methods: Carbonyl and sulfhydryl proteins, glutathione and malondialdehyde levels and the activity of the circulating xanthine oxidase were determined in: active and abstinent alcoholics, patients with chronic viral hepatitis and healthy controls. Results: Active alcoholics showed a decrease of sulfhydryl protein and glutathione concentrations in plasma, erythrocytes and ghosts compared to the other groups. Also, an increase of the carbonyl protein and malondialdehyde levels and of the activity of circulating xanthine oxidase (9.2+/-1.8 nmol min ml, p<0.001) were observed. Significant correlations between carbonyl protein and malondialdehyde concentrations in plasma (r=0.775, p<0.001), as well as between daily alcohol intake and carbonyl protein content in plasma (r=0.879, p<0.001) and erythrocytes (r=0.605, p<0.01) were observed. However, carbonyl protein levels did not correlate with the degree of liver injury. Incubation of plasma with acetaldehyde, but not with ethanol, significantly increased the carbonyl protein formation. Administration of N-Ethylmaleimide, a thiol depletor, or glutathione significantly increased or delayed, respectively, the carbonyl protein formation. Conclusions: Proteins are oxidatively modified in plasma and erythrocytes of active alcoholics, whereas no such alterations are detectable in patients with non-alcoholic liver disease. Protein oxidation in alcoholics does not seem to result directly from ethanol; circulating xanthine oxidase, delivered from injured cells, may play a contributory role and glutathione appears to be directly involved in the protection of plasma proteins against acetaldehyde toxicity
Interobserver and interequipment variability of hepatic, splenic, and renal arterial Doppler resistance indices in normal subjects and patients with cirrhosis.
No full textIF = 4.75
Measurement of mean velocity to monitor acute portal blood flow changes in portal hypertensive patients
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Study of the circle of Willis in hypertensive patients by transcranial Echo-Colour Doppler
No full textAccuratezza dell'ecografia doppler nella diagnosi di stenosi dell'arteria renale: studio comparativo in "cieco" con l'angiografia
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