195,999 research outputs found
Congenital heart block not associated with anti-Ro/La antibodies: comparison with anti-Ro/La-positive cases.
No full textJ Rheumatol. 2009 Aug;36(8):1744-8. Epub 2009 Jun 30.
Congenital heart block not associated with anti-Ro/La antibodies: comparison with anti-Ro/La-positive cases.
Brucato A, Grava C, Bortolati M, Ikeda K, Milanesi O, Cimaz R, Ramoni V, Vignati G, Martinelli S, Sadou Y, Borghi A, Tincani A, Chan EK, Ruffatti A.
Source
Medicina Interna, Ospedali Riuniti, Bergamo, Italy. [email protected]
Abstract
OBJECTIVE:
To study anti-Ro/La-negative congenital heart block (CHB).
METHODS:
Forty-five fetuses with CHB were evaluated by analysis of anti-Ro/La antibodies using sensitive laboratory methods.
RESULTS:
There were 9 cases of anti-Ro/La-negative CHB; 3 died (33.3%). Only 3 (33.3%) were complete in utero and 5 (55.5%) were unstable. No specific etiology was diagnosed. Six infants (66.6%) were given pacemakers. There were 36 cases of anti-Ro/La-positive CHB. All except 2 infants (94.4%) had complete atrioventricular block in utero. Ten died (27.8%), one (2.7%) developed severe dilated cardiomyopathy, and 26 (72.2%) were given pacemakers.
CONCLUSION:
Nine of the 45 consecutive CHB cases (20%) were anti-Ro/La-negative with no known cause. They were less stable and complete than the anti-Ro/La positive cases.
PMID:
19567621
[PubMed - indexed for MEDLINE]
PMCID: PMC279858
The antiphospholipid syndrome and infections in a child with trisomy 21.
No full textThe relationship between infections and antiphospholipid antibodies or antiphospholipid syndrome is an intriguing question. A two and a half year old child with trisomy 21, who suffered three severe episodes of thrombosis each taking place after an infection, is described here. As high titres of IgG anticardiolipin (ACL) antibodies was registered during the second and third episodes, the antiphospholipid syndrome was suspected. IgM as well as IgG and IgA ACL antibodies have been described at different titres in a wide variety of infections, although they are not usually associated with thrombosis. In this particular case the timing of events and their association with high IgG ACL antibody titres seemed to implicate infection in the pathogenesis of the antiphospholipid syndrome. It can be hypothesized that some infections not only "trigger" antiphospholipid antibody production, but--in genetically predisposed subjects--can induce the clinical manifestations of the antiphospholipid syndrome
A close relationship between infections and anti-phospholipid syndrome in a child with trisomy 21.
No full textInfluence of different IgG anticardiolipin antibody cut-off values on antiphospholipid syndrome classification
No full textRecovery from catastrophic antiphospholipid syndrome by a plasma exchange procedure: Report of four cases and review of the literature
No full textCatastrophic Antiphospholipid Syndrome (CAPS) is a rare (1%), life-threatening variant of Antiphospholipid Syndrome (APS). It has been found that the recovery rate is best when the treatment protocol includes anticoagulants, steroids and therapeutic plasma exchange (TPE). The treatment of CAPS with TPE is not, however, well defined as procedure modalities have not yet been standardized, and the best replacement fluid for TPE is still a controversial issue. Although the most commonly used one, fresh frozen plasma (FFP), contains natural anticoagulants, it is also made up of clotting factors, complement activation products and cytokines which could worsen CAPS' "thrombotic storm". The successful management of 4 CAPS patients, including TPE sessions initiated in the 1st week from diagnosis and using albumin solution as the replacement fluid, is described here. TPE was performed daily for the first 3 days, then tapered off, and withdrawn on the basis of patient's clinical condition. One of the patients was also treated with anticoagulants, while the others received anticoagulants plus high doses of steroids in addition to TPE. Our results indicate that, when initiated promptly and albumin solution is used as the replacement fluid, TPE can be considered an effective, safe treatment for CAPS
Life goast green organic agents for sustainable tanneries
No full textLIFE GOAST Green Organic Agents for Sustainable Tanneries (LIFE ENV/IT/000416) belongs to European LIFE programme which supports and promotes the research and innovation on environmental and sustainability topics. The project started on July 2017 and is an ongoing investigation, and involves the competences of three direct actors in the leather industry such as GSC Group spa as chemical supplier, Conceria Pasubio as tannery and Mediochiampo as waste-water treatment agency, in conjunction with the expertise of Università 'Ca Foscari di Venezia. It aims at demonstrating the benefits of a new tanning technology on a semi-industrial scale, particularly focusing at the tanning stage of the leather manufacture, and put itself as a more sustainable alternative to Traditional Chrome Tanning Process (TCTP). The technical feasibility of LIFE GOAST implementation, as well as its social and economic impact, have been monitored and compared with the TCTP in order to demonstrate the reduced environmental impacts of the new process, while producing comparable or better quality leather. It was then demonstrated that it was possible to treat collagen with the GOAST technology to give stabilised collagen to be used in the leather industry. A series of leather swatches were realised according to the new protocol in order to obtain preliminary information on chemical oxygen demand COD of the effluents and technical feasibility of the process. The results were remarkable: the collected waste-water generated from tanning and retanning showed COD values in line with TCTP and it was possible to obtain soft and firm grain leather despite a shrinkage temperature lower than chromium process
An analysis of experimental conditions influencing the anti-beta2-glycoprotein I ELISA assay results.
No full textCase reports of the use of immunoadsorption or plasma exchange in high-risk pregnancies of women with antiphospholipid syndrome.
No full textDr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
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