564 research outputs found
Synergistic activity of Pleconaril and Ritonavir against Coxsackievirus B4 Infection In Vitro
No full textIn the shadow of the church: the building of mosques in early medieval Syria
No full textIn his book In the Shadow of the Church: The Building of Mosques in Early Medieval Syria Mattia Guidetti examines the establishment of Muslim religious architecture within the Christian context in which it first appeared in the Syrian region, contributing to the debate on the transformation of late antique society to a Muslim one. He scrutinizes the slow process of conversion to Islam of the most important town centers by looking at religious places of both communities between the seventh and the eleventh century. The author assesses the relevancy of churches by analyzing the location of mosques and by researching phenomena of transfer of marble material from churches to mosques
RESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
No full textRESVERATROL-INDUCED AUTOPHAGY CONTRIBUTES TO THE INHIBITION OF EPSTEIN BARR VIRUS REPLICATION IN BURKITT’S LYMPHOMA CELLS
De Leo Alessandra (a), Colavita Francesca (a), Arena Giuseppe (b), Mattia Elena (a)
(a) Dip. di Scienze di Sanità Pubblica e Malattie Infettive “Sanarelli”, Univ. di Roma “Sapienza”
(b) Casa Sollievo della Sofferenza Hospital, CSS-Mendel Institute, Roma
Presenting author: De Leo Alessandra, [email protected]
We have previously examined the antiviral activity of resveratrol on the replication of Epstein Barr Virus (EBV), the etiologic agent of infectious mononucleosis and associated with several types of malignancies of epithelial and lymphoid origin.
In a cellular context that allows in vitro EBV activation and lytic cycle progression through mechanisms closely resembling those that in vivo initiate and enable productive infection, we found that RV inhibited EBV lytic genes expression and the production of viral particles in a dose-dependent manner
Prevalence and characterization of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa
No full textThe prevalence and the type(s) of metallo-beta-lactamases (MBLs) produced by isolates of Pseudomonas aeruginosa were investigated. During 2001, 506 nonduplicate isolates were obtained from hospitalized patients. Eighty-two strains were selected because of resistance to carbapenems and/or ceftazidime. Screening for MBL production was performed in the latter isolates by the Etest MBL strips (AB Biodisk, Solna, Sweden) and by a broth microdilution method measuring minimum inhibitory concentrations (MICs) of imipenem alone and in the presence of metal-chelating agents (EDTA and o-phenanthroline). Specific DNA probes were used to investigate the presence of genes coding for IMP- or VIM-type enzymes. Overall, four isolates of P. aeruginosa (obtained from independent patients) were found to carry a blaVIM gene. Polymerase chain reaction (PCR) experiments and DNA sequencing revealed that the VIM-2 determinant was present in three cases, whereas VIM-1 was detected in one isolate. Surveillance programs should be adopted to avoid the spread of these worrisome resistance genes
Does Independence Affect Regulatory Performance? The case of national competition authorities in the European Union
No full textDespite having always been assumed to be true, a relationship between the independence of regulatory agencies and their performance has never been formally tested. This paper aims at verifying whether formal regulatory independence affects the performance of national competition authorities in the EU member states. The author presents and discusses a statistical analysis which shows that greater formal independence leads competition authorities to investigate more cases and to issue more decisions
Caterina Colombini (1304 ca.-1387) o della cugina sedotta. Una ‘ricostruzione’ della figura di Caterina attraverso i testi letterari, in Le vestigia dei gesuati. L’eredità culturale del Colombini e dei suoi seguaci, a cura di I. Gagliardi, Firenze, Firenze University Press, 2020, pp. 57-71 ISBN 978-88-5518-227-0
No full textIn this essay the author demonstrates that it is possible to reconstruct the figure of Caterina Colombini (1340?-1387) – Giovanni Colombini's cousin – through a group of texts: the hagiography of Caterina, the letters sent to her by Giovanni Colombini and, finally, Giovanni's biography written by Feo Belcari. The author divides his text into four parts: the first part analyzes the content of Caterina's hagiography; the second examines the linguistic form of the hagiographic text; in the third, the author analyzes the latent meaning of the window, a symbolic place where Giovanni and Caterina converse on divine topics; in the last part, to conclude, the teachings that Giovanni gives to Catherine and her spiritual daughters – the Gesuate – are analyzed
La differenza italiana e l'aporetica del "non"
No full textIn this paper, the author discuss a recent volume on Antonio
Rosmini’s thought, and in particular around the relationship
between Rosmini and Fichte and the notion of nothingness and
nothingness of love
Prevalence and characterization of metallo-β-lactamases in clinical isolates of Pseudomonas aeruginosa
No full textpeer reviewedThe prevalence and the type(s) of metallo-β-lactamases (MBLs) produced by isolates of Pseudomonas aeruginosa were investigated. During 2001, 506 nonduplicate isolates were obtained from hospitalized patients. Eighty-two strains were selected because of resistance to carbapenems and/or ceftazidime. Screening for MBL production was performed in the latter isolates by the Etest MBL strips (AB Biodisk, Solna, Sweden) and by a broth microdilution method measuring minimum inhibitory concentrations (MICs) of imipenem alone and in the presence of metal-chelating agents (EDTA and o-phenanthroline). Specific DNA probes were used to investigate the presence of genes coding for IMP- or VIM-type enzymes. Overall, four isolates of P. aeruginosa (obtained from independent patients) were found to carry a blaVIM gene. Polymerase chain reaction (PCR) experiments and DNA sequencing revealed that the VIM-2 determinant was present in three cases, whereas VIM-1 was detected in one isolate. Surveillance programs should be adopted to avoid the spread of these worrisome resistance genes. © 2004 Elsevier Inc. All rights reserved.European Training and Mobility of Researchers Network on Metallo-beta-Lactaqmases (grant no. FMRX-CT98-0232
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