1,721,053 research outputs found
Il risarcimento del danno alla persona presso il Tribunale di Genova
No full textThe current damage-compensation system is characterized by the need of a greater protection of the individuals' physical and mental health, leaving the judge the task of establishing the real impact of the injury and toprovide a full refund for it. The > principle, which has been strongly espressed by the United Sections of the Supreme Court, requires specific medico-legal attention to the increased severity of the damage on individuals with pre-existing concurrent and/or co-existing disabilities. All this aimed at giving much more significance to the percentage of disability related to its intrinsic characteristics. In this sense the authors underline the introduction, in the Genoa Court, of the so-called > parameter which is considered more respectful of geometrical, and not purely arithmetical, progression of the permanent disability and thus the only one able to restore properly the hurt of a further disability estabished on a previously compromised anatomical and functional situation
valutazione della responsabilita’ penale del datore di lavoro in due diversi casi di tumore pleuro-polmonare in soggetti esposti ad amianto
No full textLA MEDICINA LEGALE NELLA STORIA: IL CONTRIBUTO DI ALCUNI MAESTRI ALLA NASCITA DELLA POLIZIA SCIENTIFICA IN ITALIA
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Unusual veno-venous intra-cord anastomosis in monochorionic monoamniotic twin pregnancy with unexpected preterm double stillbirth: clinical difficulties and post-mortem diagnosis
No full textClinical difficulties and forensic diagnosis: histopathological pitfalls of villus mesenchymal dysplasia in the third trimester causing foetal death.
No full textIn this article, the authors present a case of intrauterine foetal death (IUFD). The post-mortem histologic examination revealed placental mesenchymal dysplasia (PMD), a rare human placental disorder. Moreover, cases of PMD are often misdiagnosed as partial mole. The mother was a 26-year-old Italian, whose pregnancy, her first, had been uneventful until week 34+4 of gestation when IUFD suddenly occurred. The 2350 g male foetus showed no external abnormalities and the karyotype was 46, XY. The placenta weighed 450 g, the chorionic disk was round shaped, measuring 19.5-20.5 cm in diameter and had many enlarged villous structures. Histologically, the parenchyma showed abnormally enlarged and focally hydropic stem villi. Many of them were also surrounded by a fibrinoid material. Neither abnormal trophoblastic proliferation nor inclusion was observed in the examined sections. Causes and pathogenesis of PMD are still unclear and it is difficult to make a diagnosis solely on prenatal ultrasound during pregnancy. Generally, the correct diagnosis is reached only after the histological analysis of the placenta. However, obstetricians and gynaecologists should consider PMD also when a normal looking foetus is accompanied by a molar placenta (index factor for placentomegaly). The authors stress the importance of cooperation and information exchange among clinical and forensic pathologists, neonatologists, obstetricians and gynaecologists to avoid medical malpractice court proceedings in cases of IUFD
Break with tradition: donating cadavers for scientific purposes and reducing the use of sentient beings
No full textIn recent years, the development of research and the increased awareness of our moral
duties beyond the human species have pushed the scientific community to revise widely-accepted
ontological reductionist views that regard non-human animals as mere things.
The new horizons offered by the development of advanced research methods therefore
require an on-going commitment to new perspectives able to find the right balance between
the need for scientific knowledge on one hand and the respect for animal life on
the other. This is in line with increasing attention to animal welfare and expansion of the
“3Rs model”: replacement, reduction, refinement.
With the view of promoting the adoption of alternative methods, human body donation
for research can contribute not only to the acquisition of important information for human
health and for doctors’ training, but also can reduce significantly the number of
animals sacrificed.
By investigating the scientific and ethical reasons that may encourage cadaver donation,
the authors aim to promote the adoption of the practice in Italy following other European
experiences
IGF-1 abuse in sport: clinical and medico-legal aspects
No full textThe frequent revisions of prohibited substances list established by WADA are aimed at keeping up with those drugs that, being increasingly used in medicine and in sports, play on one side a therapeutic role and, on the other, a doping role.
Among the various hormone substances widely used in sports, the authors draw particular attention on IGF-1, a growth factor that is rapidly widespreading among athletes. Moreover, IGF-1 diffusion is not exclusively correlated with the doping phenomenon, being various the pathological conditions that may require the therapeutic use of this substance. As a consequence, during pathologies or medical treatments of various nature, the athletes should be informed of the IGF-1 administration because, if they are not duly apprised, they risk undergoing unjust sanctions from the competent authority. In fact, the athlete is given the possibility of communicating, before using, he is taking a medication of the WADA list for therapeutic reasons by applying for a TUE (Therapeutic Use Exemption). If this application is accepted on certified clinical grounds, the athlete will be allowed to use that substance even during sports competitions.
However, the IGF-1 detection in the athlete’s body shows, at the present state-of-art, two different problems: the first one has a technical character and concerns the differential diagnosis between the quantity of the physiologically produced substance and the quantity of the exogenously administrated substance; the second problem has an economic character and regards to the high cost of the analysis and, consecutively, the necessity of finding a well-equipped laboratory centr
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