1,721,131 research outputs found
The value of CD8 assessment in distinguishing polymyalgia rheumatica from early elderly onset rheumatoid arthritis [corrected]
No full textCorrection. Erratum in J Rheumatol 1996 May;23(5):950
Comment on: Risk factors for severe cranial ischaemic events in an Italian population-based cohort of patients with giant cell arteritis: Reply
No full textComment on: Longitudinal examination with shoulder ultrasound in patients with polymyalgia rheumatica: Reply
No full textPolymyalgia rheumatica
No full textPolymyalgia rheumatica is a clinical syndrome of unknown aetiology characterised by aching and stiffness in the shoulder girdle, pelvic girdle, and neck that occurs in people aged over 50 years. Polymyalgia rheumatica is generally associated with giant-cell arteritis, frequently occurring in the same patient. However, the nature of the association is not known. The first description of polymyalgia rheumatica was made by Bruce in 1888, who defined typical polymyalgia rheumatica clinical findings in five patients as senile rheumatic gout. Only 60 years later Bagratuni described a group of patients with polymyalgia rheumatica articular manifestations as having “anarthritic rheumatoid disease”. Bagratuni followed the clinical course of these patients for more than 10 years, and did not observe any progression in erosive arthritis; he judged this disease to be a mild form of rheumatoid arthritis. The term polymyalgia rheumatica for this disorder was suggested by Barber in 1957. During the 1960s, polymyalgia rheumatica was generally accepted as a different disease from rheumatoid arthritis and giant-cell arteritis. However, Scandinavian clinicians deem polymyalgia rheumatica to be a manifestation of a generalised arteritis and generally use the term giant-cell arteritis to define polymyalgia rheumatica/giant-cell arteritis as a whole
Erratum: The value of CD8 assessment in distinguishing polymyalgia rheumatica from early elderly onset rheumatoid arthritis (letter). (J. Rheumatol 1996;23:570-1)
No full textDiagnosis and management of polymyalgia rheumatica/giant cell arteritis
No full textThere are no standardised diagnostic criteria for polymyalgia rheumatica. The combination of persistent pain (at least 1 month) with marked morning stiffness in at least 2 of the neck, shoulder or pelvic girdle is characteristic of polymyalgia rheumatica. The other criteria are age >50 years, erythrocyte sedimentation rate (ESR) >40 mm/hour, rapid response to corticosteroids and an absence of other diseases capable of causing the musculoskeletal symptoms. A normal ESR does not exclude a diagnosis of polymyalgia rheumatica. Diagnostic temporal artery biopsy is recommended in all patients suspected of having giant cell arteritis. The segment of temporal artery with abnormality on physical examination should be biopsied. The drugs of choice in the treatment of polymyalgia rheumatica/giant cell arteritis are corticosteroids. An initial prednisone dosage of 40 to 60 mg/day is adequate in almost all cases of giant cell arteritis. Higher dosages and/or intravenous pulse methylprednisolone can be tried on patients with partial response or with recent visual loss. Polymyalgia rheumatica in the absence of giant cell arteritis requires an initial dose of prednisone 10 to 20 mg/day. In some cases of mild polymyalgia rheumatica, a short course of nonsteroidal anti-inflammatory drugs may be tried. Long term corticosteroid therapy in polymyalgia rheumatica and giant cell arteritis is complicated by serious adverse effects in between 48 and 65% of patients. Vertebral fractures and infections are among the most dangerous and frequent complications. Although there are limited data on the use of cytotoxic or immunosuppressive drugs, such as methotrexate, azathioprine and cyclosporin, in these indications, they might be effective either in sparing corticosteroids or in treating patients who do not respond to treatment with corticosteroids
Primary Sjogren's syndrome associated with chronic periaortitis
No full textWe describe the first case of primary Sjögren's syndrome in a patient with an inflammatory abdominal aortic aneurysm
Polymyalgia rheumatica
No full textTo report a population-based study in which we confirmed the presence of a subset of polymyalgia patients with normal ESR
On the utility of CD8 level assessment in the diagnosis of polymyalgia rheumatica/giant cell arteritis
No full textFocus on the utility of CD8 level assessment in the diagnosis of polymyalgia rheumatica/giant cell arteriti
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