179 research outputs found
A kinetic approach for the estimation of intracellular concentrations of nitrosative species in cells challenged by nitric oxide
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2013.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student-submitted PDF version of thesis.Includes bibliographical references.by Vasileios Theodoros Dendroulakis.Ph.D
Short-term effects of Manual Therapy on pain, disability and oxidative stress in patients with chronic mechanical neck pain
The aim of this study is to examine the possible reduction of oxidative stress levels (LOOH) in patients with chronic mechanical neck pain after manual therapy intervention
Βραχυπρόθεσμη επίδραση τεχνικών Χειροθεραπείας (Manual Therapy) στην κλινική εικόνα και στα επίπεδα του οξειδωτικού στρες σε ασθενείς με χρόνιο αυχενικό μηχανικό πόνο
ΕΙΣΑΓΩΓΗ: Ο χρόνιος μηχανικός αυχενικός πόνος μπορεί να οφείλεται σε αρκετούς παράγοντες, ένας από τους οποίους είναι και το οξειδωτικό στρες. Έχει δειχθεί ότι ένας από τους αποτελεσματικούς τρόπους βραχυπρόθεσμης αντιμετώπισης αυτού του είδους πόνου είναι η χειροθεραπεία. Η παρούσα μελέτη στοχεύει στη διερεύνηση της επίδρασης τεχνικών χειροθεραπείας στον χρόνιο μηχανικό αυχενικό πόνο και στο οξειδωτικό στρες αυτών των ασθενών. ΜΕΘΟΔΟΛΟΓΙΑ: Η μελέτη εφαρμόστηκε σε ασθενείς οι οποίοι έπασχαν από χρόνιο αυχενικό μηχανικό πόνο. Συμμετείχαν 32 εθελοντές ασθενείς, οι οποίοι χωρίστηκαν σε 3 ομάδες: 11 αποτελούσαν την ομάδα παρέμβασης και θεραπεύτηκαν με χειροθεραπεία, 11 αποτελούσαν την ομάδα εικονικής θεραπείας (SHAM χειροθεραπεία) και έλαβαν εικονική θεραπεία και 10 αποτέλεσαν μια έτερη ομάδα ελέγχου και δεν έλαβαν καμία θεραπεία. Λήφθηκαν δείγματα αίματος από τις ομάδες παρέμβασης, εικονικής θεραπείας και την έτερη ομάδα ελέγχου σε τρεις διαφορετικές συνθήκες: α) πριν την έναρξη μιας θεραπευτικής (ή της εικονικής) συνεδρίας, β) μετά από την ολοκλήρωσή της και γ) μετά την ολοκλήρωση της τελευταίας (ένατης) θεραπευτικής συνεδρίας. Η συνολική διάρκεια της μελέτης ήταν τρεις εβδομάδες και πραγματοποιήθηκαν εννέα συνεδρίες. Οι εξαρτημένες μεταβλητές της μελέτης ήταν ο πόνος, τα επίπεδα των λιπιδικών υδροϋπεροξειδίων (LOOH), ως δείκτη οξειδωτικού στρες και η λειτουργικότητα των ασθενών με χρόνιο μηχανικό αυχενικό πόνο, οι οποίες αξιολογήθηκαν στα ανωτέρω τρία χρονικά σημεία, πριν και μετά την παρέμβαση. ΑΠΟΤΕΛΕΣΜΑΤΑ: Παρατηρήθηκε μείωση των επιπέδων των LOOH στον ορό του αίματος των ασθενών ήδη από την πρώτη συνεδρία χειροθεραπείας, ενώ μεγαλύτερη μείωση παρατηρήθηκε μετά την ολοκλήρωση της ένατης θεραπείας. Οι ασθενείς που ακολούθησαν εικονική θεραπεία παρουσίασαν μικρότερη μείωση των επιπέδων των LOOH σε σύγκριση με την ομάδα παρέμβασης, η οποία παρέμεινε σταθερή ακόμη και μετά την ένατη θεραπεία. ΣΥΜΠΕΡΑΣΜΑ: Οι ασθενείς με χρόνιο μηχανικό αυχενικό πόνο στους οποίους εφαρμόστηκε χειροθεραπεία παρουσίασαν βελτίωση της κλινικής τους εικόνας, τόσο ως προς τον πόνο, όσο και ως προς τη λειτουργικότητά τους. Τα ευρήματα αυτά υποδηλώνουν ότι η χειροθεραπεία μπορεί να είναι μια αποτελεσματική μέθοδος στην αντιμετώπιση του χρόνιου μηχανικού αυχενικού πόνου και στη μείωση του οξειδωτικού στρες αυτών των ασθενών.INTRODUCTION: Chronic mechanical neck pain can be caused by several factors, one of which is oxidative stress, while it has been shown that Manual Therapy is one of the most effective ways to treat this type of pain. The present study aimed to investigate the effect of Manual Therapy techniques on chronic mechanical neck pain and oxidative stress in patients with chronic mechanical neck pain. METHODOLOGY: The study was performed on patients suffering from chronic mechanical neck pain. Thirty two volunteer patients were divided into 3 groups: 11 were the intervention group and were treated with Manual Therapy, 11 were the placebo group and received SHAM manual therapy and 10 formed another healthy control group that did not receive any treatment. Blood samples were taken from the intervention, placebo and healthy groups in three different conditions: a) before the start of a Manual Therapy (or placebo) session, b) after its completion and c) after the end of the last (ninth) treatment session. The study lasted three weeks and consisted of nine sessions. The dependent variables of the study were pain, lipid hydroperoxide (LOOH) levels as an indicator of oxidative stress, and functional ability of patients, which were evaluated at the above three time points, before and after the intervention. RESULTS: A decrease in serum LOOH levels was observed in patients after the completion of the first session of Manual Therapy, while a further decrease was observed after the end of the last treatment session. Patients that received placebo treatment exhibited a smaller reduction in LOOH compared with the intervention group, the reduction of which remained steady after the ninth treatment session. CONCLUSION: Patients with chronic mechanical neck pain showed an improvement in their clinical symptoms, both in terms of pain and functional ability, after treatment with Manual Therapy techniques. These findings suggest that Manual Therapy may be an effective method of treating chronic mechanical neck pain and reducing oxidative stress in those patients
SHORT-TERM EFFECTS OF MOBILIZATION-WITH-MOVEMENT (MWM) AND AUTO-MWM APPLICATION IN RECREATIONAL RUNNERS WITH ILIOTIBIAL BAND SYNDROME
Background: It is well known that Iliotibial band syndrome (ITBS) is the most frequent overuse injury in recreational runners. Given the fact that there are no clear guidelines on the optimal conservative treatment approach regarding ITBS rehabilitation, manual therapy effect by a functional joint mobilization is still unknown. The purpose of the study was to investigate whether implementation of mobilization-with-movement (MWM) and auto-mobilization had a significant short-term improvement in pain and functionality of recreational runners with ITBS. Methods: Participants: thirty ITBS patients, were randomly assigned into two groups. Design and Settings: One group pre-test / post-test with the control group. Interventions: Runners on the treatment group followed an MWM protocol of six sessions with an additive program of auto-MWM, while the control group received a SHAM form of MWM. Outcome measurements: Pain and functionality were measured at baseline and post-treatment, via Numeric Pain Rating scale and Lower Extremity Functional Scale respectively. Mixed-ANOVA test detected possible differences among treatment phases and between groups, but also interactions among factors. Result: The present findings revealed significant interactions between factors and significant main effects of each TIME and GROUP factors on pain and functionality. MWM-treatment group showed significant improvement in post-intervention NPRT and LEFS scores, compared to baseline scores (p<.001). SHAM- MWM group exhibited no significant differences on post-NPRT and LEFS scores, compared to baseline (p>.001). Differences between groups were significant in post-treatment scores (p<.001). Conclusion: Our findings suggest that MWM and auto-MWM are a significant treatment approach, improving pain and functionality in recreational runners suffering from ITBS
SHORT-TERM EFFECTS OF MOBILIZATION-WITH-MOVEMENT (MWM) AND AUTO-MWM APPLICATION IN RECREATIONAL RUNNERS WITH ILIOTIBIAL BAND SYNDROME
Background: It is well known that Iliotibial band syndrome (ITBS) is the most frequent overuse injury in recreational runners. Given the fact that there are no clear guidelines on the optimal conservative treatment approach regarding ITBS rehabilitation, manual therapy effect by a functional joint mobilization is still unknown. The purpose of the study was to investigate whether implementation of mobilization-with-movement (MWM) and auto-mobilization had a significant short-term improvement in pain and functionality of recreational runners with ITBS.
Methods: Participants: thirty ITBS patients, were randomly assigned into two groups. Design and Settings: One group pre-test /post-test with the control group. Interventions: Runners on the treatment group followed an MWM protocol of six sessions with an additive program of auto-MWM, while the control group received a SHAM form of MWM. Outcome measurements: Pain and functionality were measured at baseline and post-treatment, via Numeric Pain Rating scale and Lower Extremity Functional Scale respectively. Mixed-ANOVA test detected possible differences among treatment phases and between groups, but also interactions among factors.
Result: The present findings revealed significant interactions between factors and significant main effects of each TIME and GROUP factors on pain and functionality. MWM-treatment group showed significant improvement in post-intervention NPRT and LEFS scores, compared to baseline scores (p.001). Differences between groups were significant in post-treatment scores (p<.001).
Conclusion: Our findings suggest that MWM and auto-MWM are a significant treatment approach, improving pain and functionality in recreational runners suffering from ITBS
The EU’s 2030 Climate and Energy Policy Framework: How net metering slips through its net
Net metering is a support scheme for the promotion of renewable energy sources (RES) that is linked with state-of-the-art trends, especially in the field of electricity, such as distributed generation, self-consumption and energy communities. Whilst the European Union (EU) Clean Energy Package has established a more coherent and comprehensive regime for RES support schemes in general, it makes no explicit reference to net metering schemes. This raises questions as to how and under which terms net metering schemes are compatible with EU law. Against this background, this article aims to analyse the relevant EU law provisions and conduct a comparative analysis of net metering regimes in four Member States to demonstrate that the national schemes enacted and applied have significantly different design features. The article argues that a more coordinated and specific approach on net metering at the EU level should emerge.Iliopoulos, TG (corresponding author), Hasselt Univ, Rergy & Environm Law, Hasselt, Belgium
[email protected]
Short-Term Effects of Mobilization-with-Movement (MWM) and Auto-MWM Application in Recreational Runners with Iliotibial Band Syndrome
A Modular Logic Approach for Expressing Web Services in XML Applying Dynamic Rules in XML
RuleML is considered to be a markup language for the semantic web. It allows the enrichment of web ontologies by adding definitions of derived concepts and it enhances interoperability among different systems and tools by publishing rules in an XML format. Moreover the in-creasing demand for interfaces that enhance information sharing has given rise to XML doc-uments that include embedded calls to web services. In this paper we propose a variation of RuleML that is based on modular logic programming. Our approach is based in a two level architecture. In the first level a modular logic language, called M-log, is presented. This lan-guage encompasses several mechanisms for invoking web services. In the second level we ex-ploit the semantics of M-log to present a variation of RuleML with rich modeling capabilities. Formal foundations for this variation are given through direct translation to M-log semantics.Knowledge Management, XML, Modular Logic Programming, E-Services
Electrification of transportation sharing economy business models: the ride- and carsharing cases
Electrification of urban transportation is on the rise. In April 2016, ridesharing company Teo Taxi launched a plug-in electric vehicle (PEV) fleet followed four months later by Uber. In 2020 Volkswagen will start a fully-electric carsharing platform, whereas other companies such as BMW already provide such a service. When driven, an electric vehicle garners profit for the platform through transportation. When parked, it can act as a controllable storage device either consuming surplus or injecting energy to the grid. Hence, managed PEV fleets provide unique grid-support opportunities, and added profits to the platform through vehicle-to-grid services. This thesis looks into two types of sharing economy business models with electric vehicles, namely the ride- and carsharing models. The former type of platform has transactional control over the vehicles, that is, private drivers respond to monetary incentives. The latter directly controls its fleet. This thesis develops a mathematical framework to analyze the aforementioned models through queuing theory. It characterizes viable control strategies for the platforms to co-optimize their revenues from both transportation and grid services. It develops profit maximization algorithms of the PEV fleet managers providing such services. Finally, variables of interest are plotted as a function of various platform parameters.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2021-05-01The student, Theodoros Mamalis, accepted the attached license on 2019-04-05 at 13:53.The student, Theodoros Mamalis, submitted this Thesis for approval on 2019-04-05 at 14:09.This Thesis was approved for publication on 2019-04-05 at 16:34.DSpace SAF Submission Ingestion Package generated from Vireo submission #13496 on 2019-08-22 at 15:05:24Made available in DSpace on 2019-08-23T20:35:45Z (GMT). No. of bitstreams: 2
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Previous issue date: 2019-04-05Embargo set by: Seth Robbins for item 112110
Lift date: 2021-08-23T20:36:18Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Only Restriction Lifted for Item 112110 on 2021-08-24T09:15:31Z
The Short and Long-Term Effect of Weight-Bearing Mobilization-With-Movement (MWM) and Automobilization- MWM Techniques on Pain and Functional Status in Patients with Hip Osteoarthritis
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