1,720,976 research outputs found

    A case of stillbirth: the importance of placental investigation in medico-legal practice.

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    The authors present a case of stillbirth in which histologic examination of the placenta provides the opportunity to make a definitive diagnosis of a death due to fetal thrombotic vasculopathy (FTV). Establishing the etiology in cases of stillbirth may avoid medical malpractice litigation. The better knowledge of the cause of stillbirths also helped obstetricians to recognize factors that could have prejudiced future pregnancies

    Unusual suicidal smothering by means of multiple loops of adhesive gummed tape

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    In suicidal asphyxia smothering is very rare, especially when caused by winding strips of adhesive tape around the head to cover the nose and mouth. The authors report a very unusual case in which the deceased, a 66-year-old man, was found with two strips of tape wound around his head: the first, more superficial tape was wrapped six times and the second was wrapped nine times. Only integration of the crime scene data with those of the autopsy and the patient's psychological profile enabled identification of the event as suicide

    The study of specific and non specific hepatoma cells behaviour by means of plasma treated substrates

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    Physical-chemical surface modifications represent a formidable tool to drive a suitable cell behavior on materials intended to be used in the biomedical field. Plasma processes are among the more powerful methods utilized to modify the surface of materials without altering their bulk intrinsic properties. In particular, by means of plasma treatment processes it is possible to graft chemical functional groups on polymer substrate. Functional groups grafted on the surface can improve per se cell adhesion and can also represent suitable anchor sites for biomolecule immobilization. The aim of this work was to determine the effect of plasma treatment and biomolecule immobilization on Polystyrene (PS) Petri dishes on the behavior of a human hepatocellular carcinoma cell line (HepG2). For this aim Petri dishes were grafted with N-containing groups in order to obtain grafted N-functionalities, to be used as anchor groups for the immobilization of galactosamine. In this way two different modified surfaces, NH3 grafted polystyrene (PS-NH3) and polystyrene owing galactosamine moieties (PS-NH3- GalNH2), have been obtained. Differences in cell morphology, urea and plasma Fibronectin (pFN) production were clearly observed on HepG2 seeded on PS-NH3 and PS-NH3- GalNH2. These results highlight the role of specific and non specific cell response in the in vitro study of materials intended to be used for biomedical purposes

    Morti collettive da incendio di veicolo militare: proposta di linee guida per l’indagine medico-legale

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    l'accertamento della causa di morte e della identità delle vittime dell'incendio di mezzi militaristi connota di peculiari problematiche che devono essere affrontate seguendo procedure standardizzate nel rispetto di un corretto approccio metodologico ed utilizzando strutture logistiche adeguate al tipo di indagini da eseguire. In tale fattispecie di eventi infatti alle consuete difficoltà operative legale all'ampia alterazione dei cadaveri (carbonizzazione, mutilazioni, etc.) o dei luoghi si sovrappone il rischio di deflagrazione di materiale esplosivo, facente parte dell'armamento del mezzo e dell'equipaggiamento dei singoli militari coinvolti. Appare dunque operazione preliminare indispensabile la bonifica sia dell'area del sopralluogo, sia del mezzo incendiato, sia dei resti cadaverici da esaminare. Completate le operazioni di sopralluogo volte al recupero di quanto utile ai fini dell'identificazione delle vittime, è necessario che necessario che le indagini proseguano per opera di un team qualificatonello specifico settore (medici legali, odontoiatri, radiologi, antropologi, fotografi forensi) in un centro provvisto di attrezzature per la esecuzione degli accertamenti e le verifiche del cas
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