1,721,130 research outputs found
SIGNIFICATO ANATOMO CLINICO E PROGNOSI A DISTANZA DELLE METASTASI LINFONODALI DEI CARCINOMI OCCULTI TIROIDEI
No full textA study performed on 40 patients with occurrence of thyroid tissue in cervical lymph nodes yields the following: thyroid tissue found in a lymph node represents metastatic thyroid cancer; papillary carcinoma constituted 95% of all cases; a sex predominance was no manifest; the mean age was 42 yr; distant metastases were present in 10.5% of cases, but prognosis was not modified significantly; only 3 patients died and only one from metastatic thyroid cancer; the survival from surgical operation was high: more than 10 years in 17 cases (42.5%), and higher from the first symptoms (40 yr in one case); papillary carcinoma was characterized by 'ground glass nucleus'; in 81.5% of all cases, calcospherites and calcifications were present; the occurrence of atypic and giant cells was correlated with a worse prognosi
Gangliocytic paraganglioma of the duodenum: case report.
No full textA case of gangliocytic paraganglioma of the duodenum, the 25th in world medical literature, is reported. The histologic appearance consists of epithelioid cell nests resembling "Zellballen" of carotid body tumors, together with gangliocyte-like elements. Ultramicroscopically, the cytoplasm of the cells contains round electron-dense granules or a large number of filaments. Occasional cells contain both granules and filaments
[Ultrastructural aspects of the PAS-positive histiocytic giant cells of the spleen in Cooley's disease].
No full text
Tridimensional long-term finite element analysis of reinforced concrete structures with rate-type creep approach
Full text linkThis paper presents a general procedure for a rate-type creep analysis (based on the use of the continuous retardation spectrum) which avoids the need of recalculating the Kelvin chain stiffness elements at each time step. In this procedure are incorporated three different creep constitutive relations, two recommended by national codes such as the ACI (North-American) and EC2 (European) building codes and one by the RILEM research association. The approximate expressions of the different creep functions with the corresponding Dirichlet series are generated using the continuous retardation spectrum approach based on the Post-Widder formula. The proposed rate-type formulation is implemented into a 3D finite element code and applied to study the long-term deflections of a prestressed concrete bridge built in Romania, which crosses a wide artificial channel that connects the Danube river to the port of Constanta in the Black Sea
Prognostic factors in squamous cell carcinoma of the oral cavity. A retrospective study of 80 cases.
No full textA multiparameter analysis of 80 squamous cell carcinomas of the oral cavity was performed to determine the relative prognostic weight of the location of the tumor, tumor size (T), microscopic grade (G) and DNA content measured by means of flow cytometry. Tumors of the lip have an invariably favourable outcome, while at the other locations they have high rates of mortality (total 5 years of survival less than 35%). A simple statistical analysis was performed using the concepts of death sensitivity (DS), death specificity (DSp), life sensitivity (LS) and life specificity (LSp): the best measure of unfavourable outcome was represented by G3 (DS = 0.69; DSp = 1) and by DNA aneuploidy (DS = 0.76; DSp = 0.45), while the best measure of favourable outcome was represented by G1 (LS = 0.53; LSp = 0.96), T1 (LS = 0.81; LSp = 0.78) and by DNA diploidy of the tumor cells (LS = 0.45; LSp = 0.86). A survival analysis using a step by step regression model according to Cox was carried out in order to evaluate more precisely the relative importance of prognostic factors: traditional prognostic factors (histological grade = G and tumor size = T) showed a strong statistical significance, while DNA content added some additional prognostic information only if associated to the macroscopic features of the tumor
A kinematic interaction model for a large-diameter shaft foundation. An Application to Seismic Demand Assessment of a Bridge Subject to Coupled Swaying-Rocking Excitation
No full textThe aim of this paper is to illustrate an analytical model for the assessment of kinematic interaction of large-diameter shaft foundations. The model is derived using recently obtained solutions of soil structure interaction problems of rigid walls and fixed base cylinders subjected to a dynamic excitation. The proposed model constitutes an extension to a deformable base of the elastodynamic solution of a rigid, fixed-base cylinder imbedded in a homogeneous or inhomogeneous soil stratum with different lateral boundary conditions. The analytical model has been validated by means of a finite elements code and it has been implemented in a consistent seismic soil-structure-interaction analysis procedure. An application of the model to a long, multi-span continuous prestressed concrete viaduct with tall piers has been carried out focusing on the importance of kinematic interaction. The main finding of the study is that the foundation input motion is characterised not only by a translational horizontal component which is usually of a reduced amplitude if compared with the free-field ground motion, but also by a rotational component that is responsible for a large seismic demand in the superstructure. The proposed model represents an effective tool to be used in the engineering practice to assess both the seismic actions induced by the ground shaking on the foundation system and the effective input motion of a superstructure founded on massive and large diameter shafts
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