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A reappraisal of the bladder cumulative method as a reliable technique for the measurement of glomerular filtration rate
No full textBladder cumulative method for gamma camera measurement of glomerular filtration rate in humans
No full textHemodynamic effects of superficial temporal artery-middle cerebral artery by-pass studied with angioscintigraphic functional images
No full textChromatographic identification in serum of endogenously radioiodinated thyroidhormones after iodine-131 whole-body scintigraphy in the follow-up of patientswith differentiated thyroid carcinoma
No full textInvestigation on the iodination reaction of methylene blue by liquid chromatography-mass spectrometry with ionspray ionisation
No full textA reappraisal of the bladder cumulative method as a reliable technique for the measurement of glomerular filtration rate (vol 20, pg 257, 1998)
No full textIn order to quantify, the decline in renal function, repeated measurements of GFR are necessary. The conventional procedure is cumbersome and time expending so that alternative clearance techniques ave needed. We propose a simple isotopic technique for measuring GFR by Tc-99m-DTPA and external counting of the bladder by gamma camera (bladder cumulative method). This consists in the measurement by external counting of the amount of labelled filtration marker accumulated in the bladder after intravenous bolus injection. In 36 adult patients with all degrees of renal impairment (serum creatinine 0.9-9.3 mg/dL) GFR was measured twice, once by the conventional method (continuous i.v. infusion of the filtration marker and urine collection by spontaneous voiding) and once by the bladder cumulative method. Tc-99m DTPA was used in performing both methods. A satisfactory agreement was found between GFR measured by bladder cumulative method (BCM) and by conventional method (CM). The BCM averaged 60.0 +/- 36.7 mL/min and the CM +/- SD averaged 62.8 +/- 36.6 mL/mm. The ratio BCM/CM +/- SD was 0.95 +/- 0.14 (y = 0.94x + 1.14; r = 0.94). Considering the 17 patients with renal insufficiency (GFA < 60 mL/min) an even better agreement between the two methods was found. In these patients the BCM averaged 28.4 +/- 17.2 mL/min; the CM averaged 29.1 +/- 16.6 mL/min; and the ratio BCM/CM was 0.96 +/- 0.08 (y = 1.03x - 1.47; r = 0.99). The day-to-day variability of BCM, studied in another 11 patients, was lower than that of creatinine clearance (variation coefficient for duplicate measurements: 7.18 +/- 6.65 SD for BCM, 15.68 +/- 8.80 SD for CM, p < 0.01). The bladder cumulative method is a simple procedure for the accurate measurement of GFR, in particular in patients with renal insufficiency. It represents a reliable tool for estimating the decline in renal function
High sensitivity of a computerized method for estimation of left/right renal blood flow ratio
No full textDependance of left ventricular systolic pressure-volume ratio on end-diastolic volume in man: a radionuclide study
No full textCARDIAC TUMORS - VALIDITY AND LIMITATION OF NON-INVASIVE DETECTION BY 1ST PASS AND EQUILIBRIUM RADIONUCLIDE IMAGING
No full textIndium-111 Pentreotide, technetium-99m Sestamibi and iodine-131 scan in metastases of differentiated thyroid carcinoma
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