1,720,970 research outputs found
[Experience regarding the use of arginine-lysine-lactose treatment in menopausal osteoporosis].
No full textStudio mediante color Doppler della circolazione intraplacentare fetale in feti con ritardo di accrescimento intrauterino.
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Valutazione dell'influenza di una dieta "mediterranea" e della massa corporea pregravidica sull'accrescimento intrauterino
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The 'skipped generation' phenomenon in a family with renal agenesis.
No full textRenal agenesis may be unilateral or bilateral, isolated
or associated with anomalies of the internal genitalia
or other systems. Renal anomalies are often considered
sporadic. Because of their variable expressivity, only a
few cases of affected relatives have been reported. In
1934, Madisson first described affected sibs
1
; since then
more than 70 familial cases have been reported
2 – 15
.
There are no consistent phenotypic differences between
sporadic and familial renal agenesis. Even if pedigrees
suggestive of autosomal-recessive
8
, multifactorial
9
, Xlinked and polygenic
10
inheritance have been reported, the
majority appear consistent with an autosomal-dominant
inheritance with incomplete penetrance (50–90%) and
variable expressivit
Velocimetria Doppler delle arterie interlobari renali materne nell'ipertensione gravidanza indotta.
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Prevalenza di ectropion e infezione da HPV della portio in donne con vaginiti ricorrenti e donne asintomatiche
No full textAdditional investigation on the potentiation of phenytoin teratogenicity by fluconazole.
No full textFluconazole (FCZ) is a potent inhibitor of the cytochrome P450 (CYP)-mediated metabolism of the anti-epileptic agent phenytoin (PHT), a well-known human and animal teratogen. It has been postulated that phenytoin must be bioactivated via the CYP system to initiate teratogenesis. In contrast with this view, FCZ pretreatment has been previously shown to result in a potentiation of PHT teratogenesis. The current study was initiated to determine the impact of FCZ pretreatment on PHT exposure levels in maternal and embryonal compartments. HPLC analysis revealed that under a co-dosing FCZ-PHT regimen resulting in enhanced PHT teratogenesis, statistically significant higher PHT levels are detectable in maternal plasma and embryonic tissue in comparison to controls. These results further argue against a role for CYP system in teratogenic bioactivation of PHT
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