181,057 research outputs found

    I sistemi di cost management

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    Il capitolo riguarda una survey condotta sull'intero territorio nazionale e relativa alle tecniche, agli strumenti e alle metodologie di analisi e gestione dei costi realizzate dalle aziende italiane. R. Silvi ha curato i paragrafi 6.1,6.2,6.3 e 6.4; M. Bartolini i paragrafi 6. 5,6.6, 6.7,6.8,6.10.1 e l'appendice; F.Visani i paragrafi 6.9,6.9.1,6.9.2,6.9.3,6.10.2,6.10.3,6.11 e seguenti

    Bartolini, R. Paul, collection, 1918-1975

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    The R. Bartolini Collection is primarily related to Nolie Mumey’s works and the history of Colorado. The contents of this collection consist of correspondences, bibliographies, biographical material, magazines, journals, articles, clippings, research and ordering material, and some miscellaneous papers and objects.https://digitalcommons.pittstate.edu/fa/1121/thumbnail.jp

    Luoghi e itinerari del fascismo a Corridonia e Macerata

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    Che ruolo assegna il fascismo alle città marchigiane? Come si articola il rapporto tra la «modernità» del regime e le tradizioni locali? Questo volume costituisce un primo passo nella costruzione di una mappa regionale delle trasformazioni urbane in epoca fascista. Di città di fondazione nelle Marche ce ne è soltanto una, Metaurilia, e di sventramenti per far spazio a scenari monumentali, come quello di Corridonia, se ne realizzano pochi. Ma la visibilità del fascismo è comunque pervasiva, con le sue Case del Fascio, Case del Balilla, monumenti ai caduti, edifici pubblici, infrastrutture di servizio. Una serie impressionante di manufatti, connotati con immagini, simboli e iscrizioni inneggianti al regime, che proliferano capillarmente su tutto il territorio regionale. È l’impronta di un «fascismo di pietra» in «provincia», che appare oggi come una questione storiografica ancora tutta da esplorare

    Architecting for reuse: A software framework for automated negotiation

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    If agents are to negotiate automatically with one another they must share a negotiation mechanism, specifying what possible actions each party can take at any given time, when negotiation terminates and what the resulting agreements could be. The current state-of-the-art represents this as a negotiation protocol specifying the flow of messages. However, they omit other aspects of the rules of negotiation (such as obliging a participant to improve on a previous offer), requiring these to be represented implicitly in an agent's design, potentially resulting in compatibility, maintenance and re-usability problems. In this paper we propose an alternative approach, allowing all of the mechanism to be formal and explicit. We present (i) A taxonomy of declarative rules which can be used to capture a wide variety of negotiation mechanisms in a principled and well-structured way. (ii) A simple interaction protocol, which is able to support any mechanism which can be captured using the declarative rules. (iii) A software framework for negotiation, implemented in JADE [2] that allows agents to effectively participate in negotiations defined using our rule taxonomy and protocol

    Business-driven IT Management

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    Business-driven IT management (BDIM) aims at ensuring successful alignment of business and IT through thorough understanding of the impact of IT on business results, and vice versa. In this dissertation, we review the state of the art of BDIM research and we position our intended contribution within the BDIM research space along the dimensions of decision support (as opposed of automation) and its application to IT service management processes. Within these research dimensions, we advance the state of the art by 1) contributing a decision theoretical framework for BDIM and 2) presenting two novel BDIM solutions in the IT service management space. First we present a simpler BDIM solution for prioritizing incidents, which can be used as a template for creating BDIM solutions in other IT service management processes. Then, we present a more comprehensive solution for optimizing the business-related performance of an IT support organization in dealing with incidents. Our decision theoretical framework and models for BDIM bring the concepts of business impact and risk to the fore, and are able to cope with both monetizable and intangible aspects of business impact. We start from a constructive and quantitative re-definition of some terms that are widely used in IT service management but for which was never given a rigorous decision: business impact, cost, benefit, risk and urgency. On top of that, we build a coherent methodology for linking IT-level metrics with business level metrics and make progress toward solving the business-IT alignment problem. Our methodology uses a constructive and quantitative definition of alignment with business objectives, taken as the likelihood – to the best of one’s knowledge – that such objectives will be met. That is used as the basis for building an engine for business impact calculation that is in fact an alignment computation engine. We show a sample BDIM solution for incident prioritization that is built using the decision theoretical framework, the methodology and the tools developed. We show how the sample BDIM solution could be used as a blueprint to build BDIM solutions for decision support in other IT service management processes, such as change management for example. However, the full power of BDIM can be best understood by studying the second fully fledged BDIM application that we present in this thesis. While incident management is used as a scenario for this second application as well, the main contribution that it brings about is really to provide a solution for business-driven organizational redesign to optimize the performance of an IT support organization. The solution is quite rich, and features components that orchestrate together advanced techniques in visualization, simulation, data mining and operations research. We show that the techniques we use - in particular the simulation of an IT organization enacting the incident management process – bring considerable benefits both when the performance is measured in terms of traditional IT metrics (mean time to resolution of incidents), and even more so when business impact metrics are brought into the picture, thereby providing a justification for investing time and effort in creating BDIM solutions. In terms of impact, the work presented in this thesis produced about twenty conference and journal publications, and resulted so far in three patent applications. Moreover this work has greatly influenced the design and implementation of Business Impact Optimization module of HP DecisionCenter™: a leading commercial software product for IT optimization, whose core has been re-designed to work as described here

    Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC).

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    Metro G, Finocchiaro G, Toschi L, Bartolini S, Magrini E, Cancellieri A, Trisolini R, Castaldini L, Tallini G, Crino' L, Cappuzzo F. Epidermal growth factor receptor (EGFR) targeted therapies in non-small cell lung cancer (NSCLC). Reviews on recent clinical trials. 2006;1:1-13

    Bronchodilator effects of exercise hyperpnea and albuterol in mild-to-moderate asthma

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    J Appl Physiol. 2009 Aug;107(2):494-9. Epub 2009 Jun 18. Bronchodilator effects of exercise hyperpnea and albuterol in mild-to-moderate asthma. Milanese M, Saporiti R, Bartolini S, Pellegrino R, Baroffio M, Brusasco V, Crimi E. Source S.C. Pneumologia, Ospedale S. Corona, Pietra Ligure, Italy. Abstract In asthmatic patients, either bronchodilatation or bronchoconstriction may develop during exercise. In 18 patients with mild-to-moderate asthma, we conducted two studies with the aims to 1) quantify the bronchodilator effect of hyperpnea induced by incremental-load maximum exercise compared with effects of inhaled albuterol (study 1, n=10) and 2) determine the time course of changes in airway caliber during prolonged constant-load exercise (study 2, n=8). In both studies, it was also investigated whether the bronchodilator effects of exercise hyperpnea and albuterol are additive. Changes in airway caliber were measured by changes in partial forced expiratory flow. In study 1, incremental-load exercise was associated with a bronchodilatation that was approximately 60% of the maximal bronchodilatation obtainable with 1,500 microg of albuterol. In study 2, constant-load exercise was associated with an initial moderate bronchodilatation and a late airway renarrowing. In both studies, premedication with inhaled albuterol (400 microg) promoted sustained bronchodilatation during exercise, which was additive to that caused by exercise hyperpnea. In conclusion, in mild-to-moderate asthmatic individuals, hyperpnea at peak exercise was associated with a potent yet not complete bronchodilatation. During constant-load exercise, a transient bronchodilatation was followed by airway renarrowing, suggesting prevalence of constrictor over dilator effects of hyperpnea. Finally, the bronchodilator effect of hyperpnea was additive to that of albuterol. PMID: 19541736 [PubMed - indexed for MEDLINE

    A terminological "journey" in the Grey Literature domain

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    Please cite as: Bartolini R., Pardelli G., Goggi S., Giannini S., Biagioni S. A terminological "journey" in the Grey Literature domain. In: GL18 - Eighteenth International Conference on Grey Literature: Leveraging Diversity in Grey Literature. (New York, USA, 28-29 November 2016). Proceedings, pp. 117-130. Dominic Farace, Jerry Frantzen (eds.). (GL-Conference series. ISSN: 1385-2308, vol. 18). TextRelease, Amsterdam, The Netherlands, 2017. The work analyzes a corpus constituted of the entire amount of full research papers published in the GL conference series over a time-span of more than one decade (2003-2014) with the aim of creating a terminological map of relevant words in the various GL research topics. The corpus - made up of 231 research papers was processed using a Natural Language Processing (NLP) tool for term extraction . This tool is what is called a “pipeline” - that is, a sequence of different tools - which extracts lexical knowledge from texts: in short, this is a rule-based system tool for knowledge extraction and document indexing that combines Natural Language Processing (NLP) technologies for term extraction. Within our corpus made of GL articles, this NLP tool extracts a list of single (monograms) and multi-word terms (bigrams and trigrams) ordered by frequency with respect to the context

    Approaching and developing the culture of geometry theorems in school: a theoretical framework

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    Abstract. This paper is based on research work regarding the approach to geometry theorems and theories in schools carried out over the last eight years by teams in Genoa, Modena and Pisa. These studies have involved students of different age groups (from grade 5 to grade 12) and different thematic contexts. Although the specific goals of these projects differed to some extent, they did share some common features such as general goals, research methodology, epistemological analysis and cultural, cognitive and educational hypotheses. A common framework has emerged as a result of a longstanding dialectic discussion dating back to the design of our teaching experiments: this framework has brought to light some of the deep yet implicit common motives and theoretical perspectives of our independent research designs. This paper provides a unified framework of the research studies which have been reported in other papers (Bartolini Bussi, 1996; Bartolini Bussi & al, 1999; Boero et al., 1996; 1999; Garuti et al., 1996, 1998; Mariotti, 1995; 1996; Mariotti et al, 1997)

    Apricot floral biology: the evolution of dormancy and the appearance of bud anomalies in several Italian genotypes

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    Apricot (Prunus armeniaca L.) is a fruit species showing several problems related to its floral biology with inconstant and extremely low yield attributed to the lack of climatic adaptation when the unsatisfactory cropping cannot be traced to strictly genetic factors. This set of phenomena has been attributed to an unsatisfied chilling requirement and an incomplete bud dormancy overcoming leading to the appearance of flower bud anomalies. The aims of this study was to characterize a large number of native Italian apricot cultivars through the evaluation of their floral biology. In particular, the ‘Chilling Requirement’, the blooming aptitude and susceptibility to the floral anomalies were estimated. The forcing method was used to determine the Chilling Requirement of the 23 Italian germplasm genotypes and classified them into three types: low (1200). The first two cultivar types have a shorter endodormancy phase, an earlier beginning of flowering with a good blooming entity. However, these cultivars showed high percentages of early anomalous buds. The third group is composed of cultivars that show a low flowering percentage and high levels of later bud drops. It has been observed many and diversified ‘floral anomalies’, such as necrosis and pistil abortion, during bud and flower development from endodormancy to bloom, not strictly related to the chilling requirement.Apricot (Prunus armeniaca L.) is a fruit species showing several problems related to its floral biology with inconstant and extremely low yield attributed to the lack of climatic adaptation when the unsatisfactory cropping cannot be traced to strictly genetic factors. This set of phenomena has been attributed to an unsatisfied chilling requirement and an incomplete bud dormancy overcoming leading to the appearance of flower bud anomalies. The aims of this study was to characterize a large number of native Italian apricot cultivars through the evaluation of their floral biology. In particular, the ‘Chilling Requirement’, the blooming aptitude and susceptibility to the floral anomalies were estimated. The forcing method was used to determine the Chilling Requirement of the 23 Italian germplasm genotypes and classified them into three types: low (1200). The first two cultivar types have a shorter endodormancy phase, an earlier beginning of flowering with a good blooming entity. However, these cultivars showed high percentages of early anomalous buds. The third group is composed of cultivars that show a low flowering percentage and high levels of later bud drops. It has been observed many and diversified ‘floral anomalies’, such as necrosis and pistil abortion, during bud and flower development from endodormancy to bloom, not strictly related to the chilling requirement
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