39 research outputs found

    Normal male serum was spiked with 1 µM 5α-androstan-3α,17β-diol and analyzed as in Figure 1-2

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    <p><b>Copyright information:</b></p><p>Taken from "Detection of designer steroids"</p><p>Nuclear Receptor Signaling 2005;3():-.</p><p>Published online 21 Oct 2005</p><p>PMCID:PMC1402217.</p><p>Copyright © 2005, Yuan and Forman. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited. </p> Peaks corresponding to DHT (11.37 min), T (11.67 min) and 5α-androstan-3α,17β-diol (11.02 min) are noted. Control beads: black line; AR-containing beads: red line

    Are those phospholipids in your pocket?

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    The identification of phospholipids ligands for the nuclear receptors SF-1 and LRH-1 raise exciting new questions in the areas of signaling and metabolism. Do these receptors provide cells with a mechanism to alter genomic activities in response to phospholipid flux? The tools now exist to address these questions, and more

    Orphan Nuclear Receptors and Their Ligands

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    The PPARs 2001: it's not over ‘til the fat lady sings

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    Orphan Nuclear Receptors

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    (A) The single-transmembrane domain-containing full-length APP is shown along with the cleavage sites for α-, β-, and γ-secretase

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    <p><b>Copyright information:</b></p><p>Taken from "Linking lipids, Alzheimer's and LXRs?"</p><p>Nuclear Receptor Signaling 2004;2():-.</p><p>Published online 5 Apr 2004</p><p>PMCID:PMC1402230.</p><p>Copyright © 2004, Patel and Forman. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. </p> (B) Non-amyloidogenic processing of APP. α-secretase cleaves APP in the extracellular space to yield the N-terminal secreted APPα fragment and the transmembrane domain-containing α-CTF. The α-CTF is then cleaved by the γ-secretase to produce the non-amyloidogenic p3 and γ-CTF fragments. (C) Amyloidogenic processing of APP. APP is cleaved by β-secretase in the extracellular domain to produce APPβ and β-CTF. The γ-secretase can cleave β-CTF at position 40 or 42 amino-acids C-terminal to the β-secretase site. Thus, the β/γ-secretase cleavage yields the amyloidogenic Aβ40 (orange) and Aβ42 peptides (orange + red), and γ-CTF

    . 1025 Año 21 (2022) abril. El Tlacuache

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    Uno de los recursos materiales que las tradiciones médicas indígenas y afrodescendientes de América Latina y el Caribe, han empleado por siglos y milenios, son las plantas medicinales silvestres y cultivadas.- La COVID-19 y el acervo médico biocultural en Latinoamérica y el Caribe por Arturo Argueta Villamar y Gimena Pérez Ortega.Trabajos de excavación en Punta Maldonado, Guerrero. Fotografía del archivo del proyecto Excavación de la ballena en El Faro, Punta Maldonado, Cuajinicuilapa, Guerrero (Hermosillo et al.). Detalle de arreglo semillas, frutos y flores. Tomada de: Hampiy, medicina ancestral comunitaria. Recetas de prevención y tratamiento del Coronavirus Covid 19. Diseño: KAY Producciones Ecuador, 2020. Consulta: https://bit.ly/3jQhuOyCervantes Martínez, Jorge, Antonio Hermosillo Worley y Eduardo Corona-Martínez (2019). Protección, conservación y divulgación del patrimonio paleontológico. El caso de Guerrero. En El quehacer y compromiso social del INAH en el contexto Nacional, Memoria del II Congreso Nacional del Sindicato Nacional de Profesores de Investigación Científica y Docencia del INAH – La Trinidad, Tlaxcala, México, pp. 497-510. Ebert David, Marc Dando y Sarah Fowler (2013). Sharks of the world. A Complete Guide. Princeton University Press. Las fotografías forman parte del archivo del proyecto Excavación de la ballena en El Faro, Punta Maldonado, Cuajinicuilapa, Guerrero (Hermosillo et al.), excepto, los que se indican

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