1,721,068 research outputs found
A New Heterogeneous One-Pot Process for Both Nitroaldol (Henry) and Michael Reactions from Primary Haloalkanes via Nitroalkanes
No full textAt room temperature, one equivalent of primary haloalkane and aldehyde, or conjugated enone, in the presence of IRA-402 nitrite and Amberlyst A-21, gave (beta-nitroalkanols or gamma-nitro ketones, respectively, via a one-pot tandem S(N)2-nitroaldol (Henry) or S(N)2-Michael reaction
The chemistry and occurrence of taxane derivatives. XXXI. Unusual reactivity of taxine A in an oxidation-reduction protocol
No full textNitroakanes as a New, Convenient Source of 1-Acyl-2,5-dialkylbenzene Derivatives, in Two Steps.
No full textSynthesis of benzene derivatives
Amberlist A-21 an Exellent Heterogeneous Catalyst for the Conversion of Carbonyl compounds to Oximes
No full textNitraolkanes as New, Ideal Precursors for the Synthesis of Benzene Derivatives
No full textNitroalkanes have emerged, in the past few years, as powerful acyclic building blocks to synthesize polyfunctionalized benzene derivatives, avoiding any serious regiochemical ambiguities due to the activating/deactivating and orienting effects of the substituents. Many of these procedures are realized in a one-pot process or a few-step sequence. This feature article describes recent results, mainly from our group, in this fiel
Taxanes from the roots of Taxus x media cv Hicksii
No full textThe plants of genus taxus commonly known as yew tree have been used since the ancient times for their magic, poisonous and pharmacological properties.
Studies devoted to chemical constitution of extracts of several Taxus genera have been extensively developed during the last years, according to the well documented anticancer activity of taxol.
The bark of several yew species has been thoroughly investigated, but very few studies have been done on the constituents of roots. The roots of an ornamental variety of yew (T. x media cv Hicksii) gave a series of taxane and abeotaxane pseudoalkaloids. Both N-alkylated O (5) esters (taxines) and N-acylated O (13) esters (Taxols) were isolated, some of them in glycosidic form. Besides known compounds, some new taxines, taxols and abeotaxanes were isolated and their structures fully elucidated
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