1,720,975 research outputs found

    Surgical treatment of severe late radiation injury to the bowel: a retrospective analysis of 83 cases. Hepatogastroenterology. 2002 Jul-Aug;49(46):1023-6. PMID: 12143192

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    Abstract Background/Aims: The aim of this study was to determine the best surgical approach for the treatment of late radiation injury to the bowel. Methodology: Clinical and follow-up charts of 83 patients operated in our institution for late radiation injury to the bowel were retrospectively reviewed. The type of operation (resection-anastomasis or bypass) mortality, postoperative complications and reoperation rate were recorded. Seventy-six underwent resection with immediate anastomosis. A bypass or viscerolysis was performed in only 7 patients. Results: Postoperative mortality was 2.4%, morbidity was 23. Twenty-seven patients underwent further surgery; early reoperation (within 1 month) was necessary in 12 (morbidity 41%). A late reoperation has been performed in 15 patients (no mortality, morbidity 53.5%). Conclusions: From the results of our study it can be concluded that resection with immediate anastomosis for late radiation injury to the bowel is safe and should be the first option for these patients

    Total mesorectal excision for surgical treatment of rectal cancer

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    Abstract: Background and Objectives: The aim of our study was to retrospectively evaluate the results of 2 groups of patients admitted and treated for rectal cancer. Methods: One hundred and fifty-one patients were available for evaluation. Eighty (group A) were radically operated with the standard technique; 71 (group B) underwent total mesorectal excision (TME). Groups were similar according to demographics, staging, and pathological data. Mean follow-up was 73.5 months. Results: No operative mortality was observed. Complications were 15% in group A and 32% in group B. Local recurrence rates were 41.2% in group A and 12.6% in group B. Distant metastases occurred in 21.2% and 7.6%, respectively, in groups A and B. Cancer-related mortality was 62.5% in the non-TME group and 19.5% in the TME group. Overall 5-year survival rates were 32.4% in group A and 70.5% in group B. Disease-free survival rates were 25% in group A and 62.3% in group B. Conclusions: TME appears to lower the incidence of cancer-related mortality, with a higher incidence of postoperative complications. Further studies need to be done to assess the real benefits of TME in the surgical treatment of rectal cancer

    Tiroidite di Hashimoto in associazione a carcinoma della tiroide. Descrizione di un caso clinico

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    THE AUTHORS REPORT A CLINICAL CASE OF HASHIMOTO'S THYROIDITIS OCCURRING IN ASSOCIATION WITH PAPILLARY CARCINOMA OT THE THYROID GLAND
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