1,721,240 research outputs found
Biomechanics of Total Liquid Ventilation.
No full textTesi di Dottorato di Ricerca in Ingegneria Biomedic
Mechanisms mediating somatostatin-induced reduction of cytosolic free calcium in PC12 cells
No full text
Endogenous levels of serotonin and 5-hydroxyindoleacetic acid in specific areas of the pigeon CNS: effects of serotonin neurotoxins.
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Una speranza per l’assistenza ventilatoria del neonato prematuro
Full text linkLa mortalità dei neonati prematuri è considerevolmente diminuita grazie ai progressi della medicina, ma rimane alta la percentuale di neonati che, in seguito a prolungati trattamenti di ventilazione meccanica a gas, sviluppano patologie croniche polmonari. Una risposta promettente arriva dalla ventilazione liquida totale
An update on somatostatin receptor signalling in native systems and new insights on their pathophysiology
No full textThe peptide somatostatin (SRIF) has important physiological effects, mostly inhibitory, which have formed the basis for the clinical use of SRIF compounds. SRIF binding to its 5 guanine nucleotide-binding proteins-coupled receptors leads to the modulation of multiple transduction pathways. However, our current understanding of signaling exerted by receptors endogenously expressed in different cells/tissues reflects a rather complicated picture. On the other hand, the complexity of SRIF receptor signaling in pathologies, including pituitary and nervous system diseases, may be studied not only as alternative intervention points for the modulation of SRIF function but also to exploit new chemical space for drug-like molecules
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