1,721,045 research outputs found
Johann Gottlieb Walter (1734-1818) and the technical preparation of bones in an anatomical cabinet in the late eighteenth and nineteenth century
Full text linkThis study aims to analyze Johann Gottlieb Walter’s biography (1734-1818), a German physician that specialized in human anatomy, who received an award of the Göttingen Royal Academy of Sciences. Here, we describe his technique of preparing bones for educational purposes through the comparison of other widely used techniques. The article also focuses on the great historical, scientific and didactic values of the anatomical preparations. In Europe during the eighteenth century the activity of some anatomists and physiologists, who were dedicated to the realization of anatomical preparations, testified the progress of medicine in the study of the human body, fundamental knowledge for physician training
Caratterizzazione dei recettori ß-adrenergici nella muscolatura liscia dell'ileo di bovino
No full textThe "Emergency Archaeology" and the osteoarchaeological studies: the northwest lombardy research on funerary sites
Full text linkDynamic homogenization of multi-layered lattice-like metamaterials with alternate chiral microstructure
No full textThis paper presents a dynamic continualization technique for a multi-layer beam-lattice metamaterial with an alternating chiral microstructure, where each layer is reciprocally interconnected through the insertion of pins. The study analyzes the dispersive properties of the system and its potential applications as a meta-filter, highlighting how the enhanced continualization technique introduced can capture the dispersive properties of stratified systems with chiral geometry. This approach makes it possible to derive higher-order gradient-type continuum models that yield dispersion spectra close to those obtained through a discrete Lagrangian treatment, without encountering dynamic instability effects due to thermodynamic inconsistency. These aspects are further investigated through the presentation of application examples, specifically concerning a stratified tetrachiral waveguide. A key finding of the studied examples is related to the passive/active tunability of the system, specifically in relation to the stiffness of the pin which determines significant influences on the dispersion spectra. To complete the analysis, a further example is finally proposed in which the waveguide is subjected to harmonic excitation, revealing how variations in the parameters can affect wave polarizations
Pathological findings of female reproductive system following clenbuterol administration in rats and pigs.
No full textAdrenergic regulation of vascular smooth muscle tone in calf digital artery
No full textRadioligand binding studies and functional assays on isolated smooth muscle
preparations were performed in order to obtain a biochemical and functional
characterization of the b-adrenoceptor (b-AR) subtypes involved in regulation
of the smooth muscle relaxation of the calf’s common digital artery. The results
indicate that the common digital artery possesses two b-AR populations (40%
b1 and 60% b2) and the b2-subtype appears to predominate as far as function is
concerned. Only the b2-AR agonists clenbuterol and fenoterol caused doserelated
relaxant effects, antagonized by propranolol, when tested in preparations
precontracted both with PGF2a (1.4 · 10)5
M) and noradrenaline
(1.2 · 10)6
M). In noradrenaline precontracted preparations the b1-AR
selective agonists dobutamine and xamoterol caused vasodilation which was
not antagonized by (±)propranolol. While the functional relaxant effects of
dobutamine may be attributed to its potent competitive a-AR blocking activity,
further investigations are required to explain the effect of xamoterol. The
vasodilator effect of (±)isoproterenol was irregular. The recorded contractile
effects, mainly at dosages greater than 10)6
M, suggest the loss of drug
selectivity for b-AR and a-AR activation. Indirect evidence indicates that the aadrenoceptor
(a-AR) population in this tissue which produces a strong
contraction is functionally dominant over the b-AR, suggesting limited
therapeutic benefit for b-AR drugs to control blood flow disorders in the calf’s
distal limb
Caratterizzazione e distribuzione dei sottotipi recettoriali a-adrenergici nell'apparato genitale di bovina
No full textThe space of man’s death. A modern age secondary burial case in northern Italy
No full textMuch of the recent archaeological and anthropological research on Italian modern age secondary burials has focused primarily on source analysis and the funerary context descriptions. To enable a clearer understanding of these atypical burials we need more archaeological data. To comprehend the mortuary practices it is necessary to investigate the surviving funeral monuments, burials and human remains. In fact, through the correct analysis of cultural material and human remains, it is possible to highlight the taphonomic changes of the corpse experiences during the entire ritual process. This will allow us to reconstruct the modality of body treatment in the funeral ritual. Now, we know partially the diffusion of the secondary burial ritual in southern Italy, but in northern Italy, it is lesser known. In this paper, we report the results of the archaeological and anthropological investigations conducted inside the Crypt of the Franciscan Monastery of Azzio (Varese, northern Italy). In the hypogeal funerary chamber, the corpses were temporarily deposed in seat-niches. This type of burial recalls the sitting colatois (masonry seat with a hole in the center), known in Naples as “cantarelle” and largely present in southern Italy. Throughout archaeological, anthropological and historical investigations, we tried to reconstruct the ritual adopted by the Friars and to better understand the ties with other northern and southern Italian testimonies. After our investigations, we received several notices of other similar funerary monuments in northern Italy that would be worth investigating
Between medicine and faith. The history of the alleged blessed alberto besozzi and the authenticity of his relics
Full text linkThe monastery of Saint Catherine of Sasso was built overhanging the eastern shore of Lake Maggiore in the municipality of Leggiuno (VA). In particular, our paper concerns the relics housed in the Sacellum of the church of St. Caterina. According to the tradition, the first Sacellum dedicated to the saint was built before the 16th century over a medieval hermit’s ref-uge. The chronicle, the Historieta, remembers that, in the 12th century, a merchant of Arolo, Alberto Besozzi, survived the lake crossing shipwreck and made a vow to St. Catherine of Alexandria. He decided to retreat in prayer in a cave on that part of the coast. The Sacellum, now incorporated in the monastery complex (at the bottom of the central nave of the church), preserved human remains of Blessed Alberto in the past. We present the important role that the Sacellum and the relics have played not only for the faith, but also for the devotion of pilgrims and local people. In this context, this monument is related to the sense of religiosity and spirituality that pervaded medieval life, where every form of prayer is to be materialized in the physicality of a tangible creation
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