200,794 research outputs found
Sonography in early arthritis
No full textThe ability of ultrasonography to visualise soft tissue changes provides a possibility to differentiate between exudative and proliferative synovial tissue changes as well as tenosynovitis. Superficial cartilage and bone lesions can be detected earlier by ultrasonography than by conventional radiography. The application of power Doppler ultrasonography and contrast agents is especially helpful in the further differentiation of synovial changes and makes a differentiation between active and inactive inflammation possible. Musculoskeletal ultrasonography is helpful in the diagnosis of early arthritis, especially in patients with inconspicuous conventional radiography or suspicious clinical findings. It is a convenient method for follow-up analysis and therefore has impact on therapy monitoring. It is a patient friendly method and has proved to be an important tool for the diagnostic work-up of arthritis
Ultrasonographic assessment of finger and toe joint inflammation in rheumatoid arthritis: comment on the article by Szkudlarek et al
No full textMusculoskeletal ultrasonography is an examiner-dependent technique. Is this statement still valid?
No full textMusculoskeletal ultrasonography has become an established imaging technique in rheumatology, especially in the detection of early inflammation. It has been stated that the main disadvantage is its examiner-dependency. However, an inter-reader reliability between a larger number of ultrasonographers has not yet been systematically evaluated. Contrary to previous opinions, recent studies showed moderate to good inter-observer reliabilities between ultrasonographers. The kappa values were comparable to those achieved by radiologists evaluating magnetic resonance imaging. However, the studies also show that a dynamic examination of all joints and an inclusion of the palmar and dorsal sides of the finger joints are necessary. In musculoskeletal ultrasonography a differentiation between healthy and pathological tissue can roughly be performed by taking the mean with a 2-fold standard deviation of healthy tissue, a more precise cut-off can be calculated by ROC analysis with the necessity of adding data of pathological tissue
Forschungsbasierter Wissenstransfer und Gesellschaftlicher Zusammenhalt: Theorie, Empirie, Konzepte und Instrumente
No full textFücker S, Backhaus-Maul H, Grimmig M, Nuske J, Kamuf V, Quent M, eds. Forschungsbasierter Wissenstransfer und Gesellschaftlicher Zusammenhalt: Theorie, Empirie, Konzepte und Instrumente. Frankfurt a.M.: Campus; 2023
Wissen »was die Welt […] zusammenhält« – Verständigungen über nützliches Wissen
No full textFücker S. Wissen »was die Welt […] zusammenhält« – Verständigungen über nützliches Wissen. In: Backhaus-Maul H, Fücker S, Grimmig M, Kamuf V, Quent M, eds. Forschungsbasierter Wissenstransfer und Gesellschaftlicher Zusammenhalt: Theorie, Empirie, Konzepte und Instrumente. Frankfurt a.M.: Campus; 2023
Dr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
Accurate Prediction of the Response of Freshwater Fish to a Mixture of Estrogenic Chemicals
No full textReproduced with permission from Environmental Health Perspectives.Existing environmental risk assessment procedures are limited in their ability to evaluate the combined effects of chemical mixtures. We investigated the implications of this by analyzing the combined effects of a multicomponent mixture of five estrogenic chemicals using vitellogenin induction in male fathead minnows as an end point. The mixture consisted of estradiol, ethynylestradiol, nonylphenol, octylphenol, and bisphenol A. We determined concentration–response curves for each of the chemicals individually. The chemicals were then combined at equipotent concentrations and the mixture tested using fixed-ratio design. The effects of the mixture were compared with those predicted by the model of concentration addition using biomathematical methods, which revealed that there was no deviation between the observed and predicted effects of the mixture. These findings demonstrate that estrogenic chemicals have the capacity to act together in an additive manner and that their combined effects can be accurately predicted by concentration addition. We also explored the potential for mixture effects at low concentrations by exposing the fish to each chemical at one-fifth of its median effective concentration (EC50). Individually, the chemicals did not induce a significant response, although their combined effects were consistent with the predictions of concentration addition. This demonstrates the potential for estrogenic chemicals to act additively at environmentally relevant concentrations. These findings highlight the potential for existing environmental risk assessment procedures to underestimate the hazard posed by mixtures of chemicals that act via a similar mode of action, thereby leading to erroneous conclusions of absence of risk.European Commission under the 5th Framework Programme (contract EVK1-2001-00091)
"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.
No full text"Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states.
By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement.
To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports
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