86,902 research outputs found
Thermo- and pH-induced self-assembly of P(AA-b-NIPAAm-b-AA) triblock copolymers synthesized via RAFT polymerization
No full textA series of environmentally sensitive ABA triblock copolymers with different block lengths were prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization from acrylic acid (AA) and N-isopropylacrylamide (NIPAAm). The GPC and 1H NMR analyses demonstrated the narrow molecular weight distribution and precise chemical structure of the prepared P(AA-b-NIPAAm-b-AA) triblock copolymers owing to the controlled/living characteristics of RAFT polymerization. The lower critical solution temperature (LCST) of the triblock copolymers could be tailored by adjusting the length of PAA block and controlled by the pH value. Under heating, the triblock copolymers underwent self-assemble in dilute aqueous solution and formed nanoparticles revealed via TEM images. Physically crosslinked nanogels induced by inter-/intra-hydrogen bonding or core-shell micelle particles thus could be obtained by changing environmental conditions. With a well-defined structure and stimuli-responsive properties, the P(AA-b-NIPAAm-b-AA) copolymer is expected to be employed as a nanocarrier for biomedical applications in controlled-drug delivery and targeting therapy.補正完
Measurement of the Xi(-)(b) and Omega(-)(b) baryon lifetimes
No full textUsing a data sample of pp collisions corresponding to an integrated luminosity of 3 fb−1, the Ξ−b and Ω−b baryons are reconstructed in the Ξ−b → J/ψΞ− and Ω−b → J/ψΩ− decay modes and their lifetimes measured to be
τ(Ξ−b) = 1.55+0.10−0.09 (stat) ± 0.03 (syst) ps,
τ(Ω−b) = 1.54+0.26−0.21 (stat) ± 0.05 (syst) ps.
These are the most precise determinations to date. Both measurements are in good agreement with previous experimental results and with theoretical predictions
Solvability of commutative right-nilalgebras satisfying (b(aa))a=b((aa)a)*
No full textWe study commutative right-nilalgebras of right-nilindex four satisfying the identity (b(aa))a = b((aa)a). Our main result is that these algebras are solvable and not necessarily nilpotent. Our results require characteristic ≠ 2, 3, 5
Solvability of commutative right-nilalgebras satisfying (b(aa))a = b((aa)a)
No full textWe study commutative right-nilalgebras of right-nilindex four satisfying the identity (b(aa))a = b((aa)a). Ourmainresultisthatthese algebras are solvable and not necessarily nilpotent. Our results require characteristic 6≠2, 3, 5
Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection?
No full textBackground: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Methods: Retrospective investigation including all patients with prior or present IVDU that underwent renal biopsy because of chronic kidney disease between 01.04.2002 and 31.03.2012 in the city of Frankfurt/Main, Germany.
Results: Twenty four patients with IVDU underwent renal biopsy because of progressive chronic kidney disease or proteinuria. Renal AA-amyloidosis was the predominant cause of renal failure in 50% of patients. Membranoproliferative glomerulonephritis (GN) was the second most common cause found in 21%. Patients with AA-amyloidosis were more likely to be HIV infected (67 vs.17%; p=0.036) and tended to have a higher rate of repeated systemic infections (92 vs. 50%; p=0.069). Patients with AA-amyloidosis presented with progressive renal disease and nephrotic-range proteinuria but most patients had no peripheral edema or systemic hypertension. Development of proteinuria preceded the decline of GFR for approximately 1--2 years.
Conclusions: AA-amyloidosis was the predominant cause of progressive renal disease in the last 10 years in patients with IVDU. The highest rate of AA-amyloidosis observed was seen in HIV infected patients with IVDU. We speculate that chronic HIV-infection as well as the associated immunosuppression might promote development of AA-amyloidosis by increasing frequency and duration of infections acquired by IVDU
Begg’s funnel plot for publication bias test (<b>GA</b>/<b>AA</b> versus GG).
No full text<p>Begg’s funnel plot for publication bias test (<b>GA</b>/<b>AA</b> versus GG).</p
Plasma arachidonic and docosahexaenoic acids in Tunisian very low birth weight infants: status and association with selected neonatal morbidities
No full textTo study plasma arachidonic acid (AA) and docosahexaenoic acid (DHA)
status in Tunisian very low birth weight (VLBW) infants and their
association with selected neonatal morbidities. A total of 709 VLBW
infants and 339 term infants were included. Plasma fatty acids were
analyzed using capillary gas chromatography. VLBW infants had
significantly (p < 0.001) lower plasma AA (9.44 \ub1 2.12 vs. 10.8
\ub1 2.10) and DHA (2.56 \ub1 0.89 vs. 3.46 \ub1 1.09) levels,
but higher n-6:n-3 ratio (5.58 \ub1 1.22 vs. 5.17 \ub1 1.46) than
term infants. In VLBW infants, plasma AA and DHA were related to
gestational age (r = 0.156; p = 0.001 and r = 0.134; p = 0.003,
respectively), birthweight (r = 0.242; p < 0.001 and r = 0.181; p
< 0.001, respectively) and head circumference (r = 0.138; p = 0.005
and r = 0.108; p = 0.027, respectively). Infants with respiratory
distress syndrome have decreased plasma AA and DHA and those with
intraventricular hemorrhage have decreased plasma AA and n-6:n-3 ratio.
Sepsis was associated with decreased DHA levels. Plasma long chain
polyunsaturated fatty acids status is low in VLBW infants. These
deficits may enhance the risk of common neonatal morbidities, rendering
their prevention and correction greatly warranted
AA-amylodosis, cat.
No full textCongo red stain. a) Liver. A diffuse moderate amount of red stained amyloid (arrows) displaces the hepatocellular cords, sometimes isolating the hepatocytes. Inset: apple-green birefringence under polarized light. b) Spleen. Red stained amorphous material (amyloid, asterisks) is observed in the interstitium and around arteries (arrows). Inset: apple-green birefringence under polarized light. c) Kidney. The glomerular tuft is expanded by a large amount of Congo red-stained amorphous material (asterisk) consistent with amyloid, which is also present around a proximal arteriole (arrowhead) and along the Bowman’s capsule (arrows). Insets: Apple-green birefringence under polarized light is evident in a glomerulus (upper inset) and around tubules (lower inset). Histologic pictures of AA-amyloidosis-negative liver, spleen, and kidney is reported in S3 Fig.</p
AA-deficient <i>sfx</i> mice had decreased articular cartilage.
No full text(A) Representative sections of articular cartilage from control sfx/+ mice and AA-deficient sfx/sfx mice stained with Safranin-O. Articular cartilage was quantitated using the OsteoMeasure software, and sfx/sfx mice had less articular cartilage area (B) and width (C) at the femur and tibia. OARSI scores (D) are shown for sfx/+ and sfx/sfx mice. Results are presented as mean ± SEM. *P t-test), n = 6 per group.</p
Thesaurus antiquitatum romanarum : in quo continentur lectissimi quinque scriptores...
No full textEn el frontis: Petrum Van Der AA. El lugar de edición es Utrecht: en el Espasa "Ultrajectum" traject. ad RhenSign.: [*]\p6\s, 2[*]-5[*]\p4\s, 6[*]\p2\s, (a)-(b)\p4\s, A-Z\p4\s, 2A-2Z\p4\s, 3A-3R\p4\s, 3S\p3\s, A-I\p4\sPort. a dos tintas, con grab. calc.: "J. Goeree delin., J. Baptist. sculp."AntepFrontis calc.: "J. Mulder fecit"Las h. de grab. pleg. calc., son mapas, del Imperio romano de Oriente y de Occidente respectivamente, entre las col. 344-34
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