22 research outputs found
A Rare Case of Squamous Cell Carcinoma Arising in Chronic Perineal Hidradenitis Suppurativa
Chirurgia plastica e cellule staminali: il tessuto adiposo come risorsa per la medicina rigenerativa
Current developments in medicine have come to identify strategies that allow the regeneration of tissues affected by pathological phenomena. In this context we find the research on stem cells, which are equipped with the capacity to continue over time and, similarly, to give rise at least to an offspring of completely differentiated and highly specialized cells. In support of the latest advances in regenerative medicine, plastic surgery is playing an ever increasing role. Through the procedures of liposuction, the plastic surgeon provides biologist and clinician with a considerable amount of fat tissue, which is proving an extraordinary source of stem cells, useful both for plastic surgery and other fields of medicine. Adipose-derived stem cells have shown a very considerable differentiation potential. Furthermore, their easiness of taking and their abundance in the human body, makes them a potential tool with extraordinary effectiveness in tissue repairing. We already have experiences documenting that these cells have been successfully used in otorhinolaryngology, for the reconstruction of the vocal cords, in orthopedic surgery for bone defects filling, in neurosurgery, for the repair of cerebrospinal fluid loss, in colo-rectal surgery, which used the graft of adipose tissue for the treatment of sphincterial incompetence. In plastic surgery the most significant results were achieved in the treatment of radiodermatitis lesions, ulcers and for the breast reconstruction and augmentation. The purpose of this review is to examine the literature about the usefulness of adipose tissue as a source of stem cells and evaluate the studies which have already tried their use in regenerative medicine, with particular reference to plastic surgery
Il trattamento chirurgico dei nevi giganti congeniti: espansione tissutale ed escissione seriata a confronto
vengono considerati due casi del tutto simili di bambini affetti da nevo gigante congenito del dorso trattati con due diverse metodiche. nel primo caso si è ricorso all'uso di espansori, nel secondo caso si è proceduto ad escissioni seriate. i risultati ottenuti sono analoghi. tuttavia il procedimento con escissioni seriate, alla luce di una pur limitata possibilità di giudizio, appare preferibile in quanto più semplice e più sicuro
I lembi V-Y nel trattamento delle perdite di sostanza della regione naso-geniena
vengono presi in considerazioni i vantaggi che il lembo v-y con peduncolo sottocutaneo permette di ottenere nella regione naso-labio-geniena. del lembo vengono ricordati i principi su cui si basa e le modalità di scolpimento e trasferimento. alcuni casi clinici vengono riportati e illustrati a prova della bontà dei risultati che è possibile conseguire
Cross-Leg as Salvage Procedure after Free Flaps Transfer Failure: A Case Report
Posttraumatic wounds of the lower leg with soft tissue defects and exposed fractures are a reconstructive challenge due to the scarce availability of local tissues and recipient vessels. Even when a free tissue transfer can be performed the risk of failure remains considerable. When a free flap is contraindicated or after a free flap failure, the cross-leg flap is still nowadays a possible option. We report a case of a male with a severe posttraumatic wound of the lower leg with exposed tibia fracture firstly treated with two consecutive latissimus dorsi muscular free flaps, failed for vascular thrombosis; the coverage was then achieved with a cross-leg flap with acceptable results
Fat grafting for breast cancer patients: From basic science to clinical studies
Fat grafting in the surgical treatment of breast cancer has become popular in a short period of time because of the rising expectations of good esthetic results by the patients as well as the simplicity of the technique; however, the oncological safety for breast cancer patients remains a matter of debate. The procedure raises many questions considering that recent in-vitro studies have shown that fat grafting could promote tumor recurrence through diverse mechanisms, or even facilitate distant metastasis. We present a review of the currently available experimental and clinical data in order to describe and discuss patient selection criteria following breast cancer surgery
Rinocheilognatoschisi monolaterale: approccio globale alla dismorfia della punta nasale
The correction of nasal tip deformities, always combined with cleft lip, so that some authors the prefere the term rynocheilognatoschisis, is one of the most difficult and controversial issues in plastic surgery procedures for face malformation.The nose is a crucial feature in the harmony of the face and there is a vast literature on the numerous surgical corrective techniques, concerning both methodologies and timing. As a regards the time of correction we divide rhinoplasty into: primary rhinoplasty, performed at the time of primary lip surgery repair, intermediate rhinoplasty, performed between first and second childhood and final rhinoplasty, performed after completion of the development of the face. The purpose of this paper is to describe the pathological anatomy of nasal deformities in unilateral rinocheilognatoschisis and to illustrate the global methodology implemented by the Bologna school, made up of three distinct phases of treatment: pre-surgical modeling, surgery and post-surgical shaping.It aims to describe how the treatment of nasal deformities combined with cleft lip has been developed in the Bologna school over the last twenty years, through the analysis of functional and aesthetic results achieved in the treatment of 70 clinical cases, from 1988 to data, in the Center for Dismorphopaties Plastic Surgery/Center for the Treatment of Malformations.The main objective of the article is to compare the results achieved through the global technique with those obtained through the merely surgical traditional procedure used in the past.On the basis of the data obtained we can conclude that an early use of pre-surgical procedures and of their surgical variant currently applied in the Bologna school has allowed to achieve very good both on functional and aesthetic level. These procedures have actually resulted in a series of short and long term benefits, which mainly concern the correction of nose/lip/ labial deformities, and have significantly reduced complexity and invasiveness of secondary corrective surgery, which can thus be performed on a more stable and symmetric background. Finally they have also reduced the price to be paid in terms of residual scars, length of stay in hospital and surgery morbidity. These results are optimized by Psychological Assistance that influence in determining the future life in terms of adaptation and social interaction, appearance, self-esteem, emotional conditioning, behavioural and even cognitive, conditioning therefore, in a positive way, the quality of life of young patients and their families
Comparison of 2 commercial turkey hybrids: productivity, occurrence of breast myopathies, and meat quality properties
This study was undertaken to compare productive performance, occurrence of breast myopathies, chemical composition, and technological properties of the meat in 2 dominant commercial turkey hybrids. A total of 972 1-day-old male turkey poults (equally divided in hybrid A and B) were randomly distributed in 18 floor pens.
Overall, productive performance resulted similar between the genotypes, although they showed different growth profile (turkeys from group B grew up faster up to 84 d). Regarding the occurrence of myopathies, the percentage of breasts affected by white striping was markedly higher in both genotypes (46 vs. 60% of severe lesions, respectively for A and B; P < 0.05), while the occurrence of spaghetti meat-like condition was negligible. The histological features of the different categories of meat abnormalities resulted similar to those previously described for chicken hybrids.
The technological traits such as ultimate pH, lightness, redness, marinade uptake, cooking losses, and shear force were not significantly affected by the genotype. However, turkeys from group B exhibited lower yellowness (b*, 0.50 vs. 1.04; P < 0.05) and higher drip losses (1.34 vs. 1.26%; P < 0.05). The shelf-life test on thigh meat showed no significant changes in meat color over the storage time in both hybrids, whereas thigh meat from group A showed absolute lower values of lightness (L*) and yellowness (b*) (P < 0.05). Lipid oxidation of thigh meat significantly increased during storage, although no significant difference was found between the hybrids. Proximate composition and intramuscular collagen properties resulted similar between genetic lines with the exception of total fat content (1.55 vs. 1.21%, respectively for A and B; P < 0.05). The genotype had a moderate effect on fatty acid families of breast meat as only monounsaturated fatty acid content was significantly affected (31.7 vs. 29.8%, respectively for A and B). In conclusion, the overall productive traits of commercial turkeys, including the occurrence of muscle myopathies, as well as quality attributes of fresh and refrigerated meat were only slightly affected by the genotype
