397 research outputs found
Friends of St. Mike's 1936-8 B
No full textSaint Michael's College boosters pose on steps of Jeanmarie Hall
When Supply Does Not Meet Demand-ER Stress and Plant Programmed Cell Death
No full textThe endoplasmic reticulum (ER) is the central organelle in the eukaryotic secretory pathway. The ER functions in protein synthesis and maturation and is crucial for proper maintenance of cellular homeostasis and adaptation to adverse environments. Acting as a cellular sentinel, the ER is exquisitely sensitive to changing environments principally via the ER quality control machinery. When perturbed, ER-stress triggers a tightly regulated and highly conserved, signal transduction pathway known as the unfolded protein response (UPR) that prevents the dangerous accumulation of unfolded/misfolded proteins. In situations where excessive UPR activity surpasses threshold levels, cells deteriorate and eventually trigger programmed cell death (PCD) as a way for the organism to cope with dysfunctional or toxic signals. The programmed cell death that results from excessive ER stress in mammalian systems contributes to several important diseases including hypoxia, neurodegeneration and diabetes. Importantly, hallmark features and markers of cell death that are associated with ER stress in mammals are also found in plants. In particular, there is a common, conserved set of chaperones that modulate ER cell death signalling. Here we review the elements of plant cell death responses to ER stress and note that an increasing number of plant-pathogen interactions are being identified in which the host ER is targeted by plant pathogens to establish compatibility
A G-rich sequence within the 3'UTR of KiSS1 forms G-quadruplex
No full textL’obiettivo dello studio è stato quello di dimostrare che la regione ricca in guanine del 3’UTR del gene KiSS1 forma effettivamente strutture secondarie G-quadruplex e di capire se i polimorfismi trovati nei pazienti affetti da pubertà precoce interferiscono con la formazione di queste strutture e quindi con la regolazione del gene. È stato anche iniziato uno studio preliminare sulle potenziali interazioni tra proteine e i G-quadruplex di KiSS1
Measurement of the Reaction E+e--]eta-pi+pi- In the Center of Mass-energy Interval 1350-2400 Mev
No full textMormon women and depression
No full textThis study investigates the prevalence and level of depression among Mormon women compared to non-Mormon women. The hypothesis states that the incidence of depression will be higher among LDS women than non-LDS women. A significant negative relationship is predicted to exist between religious practice and depression where the less they practice, the more depressed they would tend to be; A random sample of 45 LDS and 49 non-LDS women were given a survey instrument to measure their level and rate of depression and their degree of religious belief and practice. LDS women appear to be more depressed than the rest of the Christian women in the sample. The results indicated, that LDS women who do not practice their religion, report higher rates of depression than other women. Also, those who practiced their religion appeared to be less depressed than those who did not. (Abstract shortened with permission of author.)
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Drafting indemnity provisions in oil and gas contracts ::analysis and application of Texas and Louisiana case law to offshore contracts /
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