2,459 research outputs found
Letter from Frederick Fick to James B. Finley
No full textFick sent Finley a letter which was not answered, so he is writing again. Fick says that when he came to Cincinnati, he and his wife joined the church and are members in good standing. In fact, he is Secretary of the Sunday School. His business of house painting is very good and he has three employees. He now lives on Everett Street and would welcome a visit from Finley. Fick asks Finley to pass on greeings to friends and shop mates. Abstract number - 1146https://digitalcommons.owu.edu/finley-letters/2130/thumbnail.jp
An Interview with Marlon L. Fick
No full textA conversation with a Fellow for the National Endowment for the Arts in Writing for the United States as well as Mexico (ConaCulta), Marlon L. Fick. Fick is the author of several books, including translations, volumes of poetry, and short fiction. He is the author of two forthcoming novels from Jaded Ibis Press - the two novels are part of a trilogy with the third underway. The novels, The Nowhere Man and Rhapsody in a Circle, are written against a backdrop of twentieth-century political turmoil in third world countries: The Congo (then Zaire), Nicaragua, Mexico, and Pakistan. Although at the heart of both novels lies questions of identity, the potentially futile quest for the soul, the theme of individuality and freedom eventually collides with politics. Fick believes we are prisoners of the body politic. The author does not like to speak of the novel as history, except to assert that 'history is a poor word for something for which we have yet to find a better word'
Hyperoxia reversibly alters oxygen consumption and metabolism
No full textAim: Ventilation with pure oxygen (hyperoxic ventilation: HV) is thought to decrease whole body oxygen consumption (VO(2)). However, the validity and impact of this phenomenon remain ambiguous; until now, under hyperoxic conditions, VO(2) has only been determined by the reverse Fick principle, a method with inherent methodological problems. The goal of this study was to determine changes of VO(2), carbon dioxide production (VCO(2)), and the respiratory quotient (RQ) during normoxic and hyperoxic ventilation, using a metabolic monitor.
Methods: After providing signed informed consent and institutional acceptance, 14 healthy volunteers were asked to sequentially breathe room air, pure oxygen, and room air again. VO(2), VCO(2), RQ, and energy expenditure (EE) were determined by indirect calorimetry using a modified metabolic monitor during HV.
Results: HV reduced VO(2) from 3.4 (3.0/4.0) mL/kg/min to 2.8 (2.5/3.6) mL/kg/min (P < 0.05), whereas VCO(2) remained constant (3.0 [2.6/3.6] mL/kg/min versus 3.0 [2.6/3.5] mL/kg/min, n.s.). After onset of HV, RQ increased from 0.9 (0.8/0.9) to 1.1 (1.0/1.1). Most changes during HV were immediately reversed during subsequent normoxic ventilation.
Conclusion: HV not only reduces VO(2), but also increases the respiratory quotient. This might be interpreted as an indicator of the substantial metabolic changes induced by HV. However, the impact of this phenomenon requires further study
Il sacco di Roma nel 1527 : relazione del commissario imp. Mercurino Gattinara
No full textricavata da un manoscritto del barone di Mirabello Giovanni Antonio Trasmondo, pubblicata a cura del cav. G. B. G. Galiffe, et del cav. Odoardo Fick ..
Comparison of Fick and thermodilution cardiac output determinations in standing horses
No full textThe Fick and thermodilution (TD) methods are two currently popular techniques for determination of cardiac output (CO) in adult horses. To our knowledge, a comparison of these two techniques has not been reported. Six healthy, resting, fit, adult horses of either sex and weighing 516.5 ± 33.2 kg (mean ± SD) were instrumented to enable measurement of cardiac output. Resting CO was determined by the Fick method and by thermodilution while the horses stood quietly in the stocks. Fick and thermodilution CO measurements were repeated under conditions of increased cardiac output achieved with the use of a dobutamine infusion (5 μg kg−1 min−1, IV), and again under conditions of decreased CO induced by administration of xylazine (0.5 mg/kg, IV). Fick and thermodilution cardiac outputs were compared using Bland–Altman analysis for repeated measures. The mean of the differences ± 1.96SD (bias and precision) between the two techniques was 1.88 ± 24.17 L/min. Variability between measurements with the two techniques was decreased to 3.41 ± 46.78 mL kg−1 min−1 when CO was normalized for body size by calculation of cardiac index.Mauricio Loría Lépiz, Robert D. Keegan, Warwick M. Bayly, Stephen A. Greene, and Margaret-Mary McEwe
Environmental fate of the antiviral drug Tamiflu in two aquatic ecosystems
No full textThe antiviral drug Tamiflu (Oseltamivir Phosphate, OP), has been indicated by the World Health Organization
as a first-line defense in case of an avian influenza pandemic. Recent studies have demonstrated
that Oseltamivir Carboxylate (OC), the active metabolite of the prodrug OP, has the potential to be
released into water bodies. The present laboratory study focused on basic processes governing the environmental
fate of OC in surface water from two contrasting aquatic ecosystems of northern Italy, the
River Po and the Venice lagoon.
Results of this study confirmed the potential of OC to persist in surface water. However, addition of 5%
of sediments resulted in rapid OC degradation. Estimated half-life of OC in water/sediment of the River Po
was 15 days. After three weeks of incubation at 20 C, more than 8% of 14C-OC evolved as 14CO2 from
water/sediment samples of the River Po and Venice lagoon. At the end of the 21-day incubation period,
more than 65% of the 14C-residues were recovered from the liquid phase of both Po and Venice water/sediment
samples. OC was moderately retained onto coarse sediments from the two sites. In water/sediment
samples of the River Po and Venice lagoon treated with 14C-OC, more than 30% of the 14C-residues
remained water-extractable after three weeks of incubation. The low affinity of OC to sediments suggests
that presence of sediments would not reduce its bioavailability to microbial degradation
Theorien, Konzepte und Anwendungsfelder der inklusiven Pädagogik
No full textSchwab S, Gebhardt M, Ederer-Fick EM, Gasteiger-Klicpera B, eds. Theorien, Konzepte und Anwendungsfelder der inklusiven Pädagogik. Wien: Facultas-Verlag; 2013
Cardiac output during exercise by the open circuit acetylene washin method: comparison with direct Fick
No full textAn open-circuit (OpCirc) acetylene uptake cardiac output (Q˙t) method was modified for use during exercise. Two computational techniques were used. OpCirc1 was based on the integrated uptake vs. end-tidal change in acetylene, and OpCirc2 was based on an iterative finite difference modeling method. Six subjects [28–44 yr, peak oxygen consumption (V˙o2) = 120% predicted] performed cycle ergometry exercise to compareQ˙t using OpCirc and direct Fick methods. An incremental protocol was repeated twice, separated by a 10-min rest, and subsequently subjects exercised at 85–90% of their peak work rate. Coefficient of variation of the OpCirc methods and Fick were highest at rest (OpCirc1, 7%, OpCirc2, 12%, Fick, 10%) but were lower at moderate to high exercise intensities (OpCirc1, 3%, OpCirc2, 3%, Fick, 5%). OpCirc1 and OpCirc2 Q˙t correlated highly with Fick Q˙t( R2= 0.90 and 0.89, respectively). There were minimal differences between OpCirc1 and OpCirc2 compared with Fick up to moderate-intensity exercise (<70% peakV˙o2); however, both techniques tended to underestimate Fick at >70% peakV˙o2. These differences became significant for OpCirc1 only. Part of the differences between Fick and OpCirc methods at the higher exercise intensities are likely related to inhomogeneities in ventilation and perfusion matching ( R2= 0.36 for Fick − OpCirc1 vs. alveolar-to-arterial oxygen tension difference). In conclusion, both OpCirc methods provided reproducible, reliable measurements ofQ˙t during mild to moderate exercise. However, only OpCirc2 appeared to approximate FickQ˙t at the higher work intensities.</jats:p
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