6,996 research outputs found
Recommended from our members
Charles B. Moore Family papers, 1832-1917
No full textA letter from Hubert and Theresia Sauer of Fillmore County, NB to Charles B. Moore. It details the difficult times Nebraskan farmers were having
Charles B. Moore Family papers, 1832-1917
No full textA letter from Hubert and Theresia Sauer of Fillmore County, NB to Charles B. Moore. It details the difficult times Nebraskan farmers were having
Charles B. Moore Family papers, 1832-1917
No full textAn envelope which contained a letter to C.B. Moore. A not on the left bottom corner reads: "Hubert + Theresa Sauer; Received Feb 21st; 1875.
Recommended from our members
Charles B. Moore Family papers, 1832-1917
No full textAn envelope which contained a letter to C.B. Moore. A not on the left bottom corner reads: "Hubert + Theresa Sauer; Received Feb 21st; 1875.
Data for Reduced snow and increased nutrients show enhanced ice-associated photoautotrophic growth using a modified experimental under-ice design
No full text1. File List
A. Filename: NDS_chl.csv
Short description: chlorophyll-a concentrations across snow treatments and nutrient treatments for the 21 day experiment and 25 day experiment.
B. Filename: 16S_Sequences zipped folder
Short description: folder containing 8 fastq files for 4 paired-end 16S V4 amplicon sequencing samples. Files are named based on their nutrient treatment replication and are for the 25 day experiment.
C. Filename: 18S_Sequences zipped folder
Short description: folder containing 8 fastq files for 4 paired-end 18S V9 amplicon sequening samples. Files are named based on their nutrient treatment replication and are for the 25 day experiment.
2. Relationship between files: The main dataset is "NDS_chl.csv" and has chlorophyll-a concentrations for all NDS deployed in the experiment. The 18S_Sequences and 16S_Sequences are the 18S and 16S data from a subset of NDS.We modified an existing stream method to create a novel under-ice approach by deploying nutrient diffusing substrates (single nutrient amendments, nitrogen or phosphorus; combined enrichment of nitrogen and phosphorus) under two different light scenarios (snow covered, reduced light; snow removed, increased light) near the water-ice interface to mimic the habitat of ice-associated photoautotrophs.
The data associated with the nutrient diffusing substrates are: chlorophyll a concentrations, 16S, and 18S.H.M.S received support from NSF grant #1948058Knoll, Lesley, B; Fry, Benton; Hayes, Nicole, M; Sauer, Hailey, M. (2023). Data for Reduced snow and increased nutrients show enhanced ice-associated photoautotrophic growth using a modified experimental under-ice design. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/d00x-4m78
Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients
No full textCurrent treatment of hematologic malignancies involves rather unspecific chemotherapy, frequently resulting in severe adverse events. Thus, modern clinical research focuses on compounds able to discriminate malignant from normal tissues. Being expressed in newly formed blood vessels of solid cancers but not in normal mature tissues, the extradomain B of fibronectin (ED-B FN) is a promising target for selective cancer therapies. Using immunohistology with a new epitope retrieval technique for paraffin-embedded tissues, ED-B FN expression was found in biopsies from more than 200 Hodgkin and non-Hodgkin lymphoma patients of nearly all entities, and in patients with myeloproliferative diseases. ED-B FN expression was nearly absent in normal lymph nodes (n = 10) and bone marrow biopsies (n = 9). The extent of vascular ED-B FN expression in lymphoma tissues was positively correlated with grade of malignancy. ED-B FN expression was enhanced in lymph nodes with severe lymphadenopathy and in some hyperplastic tonsils. The in vivo accessibility of ED-B FN was confirmed in 3 lymphoma patients, in whom the lymphoma lesions were visualized on scintigraphy with (131)I-labeled L19 small immunoprotein ((131)I-L19SIP). In 2 relapsed Hodgkin lymphoma patients(131)I-L19SIP radioimmunotherapy induced a sustained partial response, qualifying ED-B FN as a promising target for antibody-based lymphoma therapies
Reconstructing the evolutionary history of the radiation of the land snail genus Xerocrassa on Crete based on mitochondrial sequences and AFLP markers
No full textSauer J, Hausdorf B. Reconstructing the evolutionary history of the radiation of the land snail genus Xerocrassa on Crete based on mitochondrial sequences and AFLP markers. BMC Evolutionary Biology. 2010;10(1): 299.Background: A non-adaptive radiation triggered by sexual selection resulted in ten endemic land snail species of the genus Xerocrassa on Crete. Only five of these species and a more widespread species are monophyletic in a mitochondrial gene tree. The reconstruction of the evolutionary history of such closely related species can be complicated by incomplete lineage sorting, introgression or inadequate taxonomy. To distinguish between the reasons for the nonmonophyly of several species in the mitochondrial gene tree we analysed nuclear AFLP markers. Results: Whereas six of the eleven morphologically delimited Xerocrassa species from Crete are monophyletic in the mitochondrial gene tree, nine of these species are monophyletic in the tree based on AFLP markers. Only two morphologically delimited species could not be distinguished with the multilocus data and might have diverged very recently or might represent extreme forms of a single species. The nonmonophyly of X. rhithymna with respect to X. kydonia is probably the result of incomplete lineage sorting, because there is no evidence for admixture in the AFLP data and the mitochondrial haplotype groups of these species coalesce deeply. The same is true for the main haplotype groups of X. mesostena. The nonmonophyly of X. franciscoi might be the result of mitochondrial introgression, because the coalescences of the haplotypes of this species with some X. mesostena haplotypes are shallow and there is admixture with neighbouring X. mesostena. Conclusion: The most likely causes for the nonmonophyly of species in the mitochondrial gene tree of the Xerocrassa radiation on Crete could be inferred using AFLP data by a combination of several criteria, namely the depth of the coalescences in the gene tree, the geographical distribution of shared genetic markers, and concordance with results of admixture analyses of nuclear multilocus markers. The strongly subdivided population structure increases the effective population size of land snail species and, thus, the likelihood of a long persistence of ancestral polymorphisms. Our study suggests that ancestral polymorphisms are a frequent cause for nonmonophyly of species with a strongly subdivided population structure in gene trees
Sauer (Cari Ortwin) : Sixteenth Century North America. The Land and the People as Seen by the Europeans
No full textWeber B. C. Sauer (Cari Ortwin) : Sixteenth Century North America. The Land and the People as Seen by the Europeans. In: Revue française d'histoire d'outre-mer, tome 60, n°219, 2e trimestre 1973. p. 283
Single-Molecule STED Microscopy with Photostable Organic Fluorophores
No full textKasper R, Harke B, Forthmann C, Tinnefeld P, Hell SW, Sauer M. Single-Molecule STED Microscopy with Photostable Organic Fluorophores. SMALL. 2010;6(13):1379-1384
- …
