30 research outputs found
Unusual choroidal vessels in neurofibromatosis type 1 observed with near infrared reflectance and spectral domain optical coherence tomography
No abstract availabl
A review of the role of ultrasound biomicroscopy in glaucoma associated with rare diseases of the anterior segment
Giuseppe Mannino,1 Barmak Abdolrahimzadeh,2 Silvia Calafiore,1 Gianmario Anselmi,1 Cristina Mannino,1 Alessandro Lambiase3 1Ophthalmology Unit, Saint Andrea Hospital, Department of Neurosciences, Mental Health and Sense Organs, University of Rome “Sapienza”, Rome, Italy; 2Polimed Beltramelli Medical Centre, Rome, Italy; 3Department of Sense Organs, Ophthalmology Unit, University of Rome “Sapienza”, Rome, Italy Abstract: Ultrasound biomicroscopy is a non-invasive imaging technique, which allows high-resolution evaluation of the anatomical features of the anterior segment of the eye regardless of optical media transparency. This technique provides diagnostically significant information in vivo for the cornea, anterior chamber, chamber angle, iris, posterior chamber, zonules, ciliary body, and lens, and is of great value in assessment of the mechanisms of glaucoma onset. The purpose of this paper is to review the use of ultrasound biomicroscopy in the diagnosis and management of rare diseases of the anterior segment such as mesodermal dysgenesis of the neural crest, iridocorneal endothelial syndrome, phakomatoses, and metabolic disorders. Keywords: glaucoma, rare diseases, ultrasound biomicroscopy, neural crest, iridocorneal syndrome, phakomatoses, metabolic disorders 
Spectral domain optical coherence tomography and B-scan ultrasonography in the evaluation of retinal tears in acute, incomplete posterior vitreous detachment
BACKGROUND: The purpose of this study was to evaluate the extension and traction
effects of posterior vitreous detachment (PVD) complicated with retinal tears
using spectral domain optical coherence tomography (OCT) and B-scan
ultrasonography.
METHODS: Complete ophthalmological examination, B-scan ultrasonography and
spectral domain OCT were performed in patients with acute PVD and retinal tears.
Vitreous detachment was classified as complete or incomplete, based on extent of
posterior pole or peripheral vitreous detachment. Retinal tear location and
persistent traction on the retinal flap was evaluated with B-scan ultrasonography
and OCT. Categorical data were evaluated with Fisher's exact test. Statistical
significance was considered as P < 0.05.
RESULTS: Twenty-six eyes of 25 patients were assessed. Four eyes (15 %) presented
complete PVD with detachment at the posterior pole and periphery. 22 eyes (85 %)
presented incomplete PVD with detachment in the periphery. Twenty eyes presented
retinal tears in the superior quadrants with respect to only 6 in the inferior
quadrants (p = 0.006). There was a higher incidence of retinal tears in the pre
with respect to post-equatorial areas (19 vs 7 eyes, p = 0.019). B-scan
ultrasonography and OCT revealed persistent traction on the retinal tear flap in
19 and 15 eyes, respectively.
CONCLUSIONS: In acute PVD, retinal tears are prevalently associated with
peripheral vitreous detachment. The impact of complete or incomplete PVD can be
of clinical value when evaluating patients with retinal tears
Bilateral diffuse choroidal hemangioma in Sturge Weber syndrome: a case report highlighting the role of multimodal imaging and a brief review of the literature
Purpose: The purpose of this paper is to present a patient with bilateral choroidal hemangioma in Sturge-Weber syndrome (SWS) and highlight multimodal imaging techniques for early detection and management of ocular alterations. Methods: A 37-year-old woman with diagnosis of SWS presented to our unit. The patient had been treated with pulsed dye laser for bilateral nevus flammeus and had right leptomeningeal angiomatosis. She had glaucoma, but ultrasound biomicroscopy did not show anterior chamber or ciliary body alterations. Results: Enhanced depth imaging (EDI) spectral domain optical coherence tomography (SD-OCT) showed bilateral diffuse choroidal hemangiomas in both eyes with choroidal thickness above 1000 μm. B-scan ultrasound examination showed diffuse choroidal hemangioma in both eyes, with a choroidal thickness of 1.53 mm and 1.94 mm in the right and left eye (RE, LE), respectively. Peripapillary retinal nerve fiber evaluation showed thinning of the retinal nerve fiber layer in both eyes. Conclusions: This report highlights multimodal imaging techniques for the critical assessment of patients with SWS, especially in rare cases with bilateral choroidal hemangioma of the choroid. Novel imaging modalities enable optimal management and follow-up of rare conditions, and our case adds further evidence to the existing literature
An epidemiological investigation on hospital admissions for cataract surgery in Italy since 1986.
Efficacy of preoperatory systemic Clonidine administration for IOP reduction in ophthalmic surgery
Abstract: A case-control study was performed in 214 eyes to evaluate the reduction of intraocular pressure (IOP) produced by oral administration of clonidine before cataract surgery and combined cataract-glaucoma surgery. Group I was composed of 109 eyes that were operated on after systemic clonidine administration. Group 2 included 105 control eyes operated on without clonidine premedication. A reduction of IOP was observed after clonidine administration and during anesthesia induction
Correlation between steroid hormone balance and etiopathology of high myopia: clinical trial
The purpose of this study was to determine the relationship between steroid hormone balance in fertile women and the progression of high myopia. Variations of cortisol, progesterone, and estradiol were evaluated. A case-control clinical trial was conducted on two groups of subjects. The first group included patients affected by high myopia (with insufficient optical correction). The control group was composed of emmetropic or hypermetropic women of the same age group. We observed increased serum cortisol levels in the women with high myopia, whereas progesterone and 17- b-estradiol did not differ between the two groups. The significantly higher cortisol values in the group with high myopia supported Balacco Gabrieli's theory on the role of hormonal balance in the progression of high myopia
