2 research outputs found
A STUDY TO CORRELATE SERUM ANTI MULLERIAN HORMONE, BASAL FOLLICLE STIMULATING HORMONE AND ANTRAL FOLLICLE COUNT IN PRIMARY INFERTILITY AS A MEASURE OF OVARIAN RESERVE
No full textObjectives: This study aims to find the correlation between anti mullerian hormone (AMH) and follicle stimulating hormone (FSH) and to observe the above mentioned hormones relation with antral follicle count (AFC) in patients with primary infertility.
Methodology: This is a cross-sectional correlation study in which 60 patients with primary infertility meeting inclusion criteria, attending infertility clinic in Chalmeda Ananda Rao Institute Of Medical Sciences, Karimnagar, between October 2020and April 2022 were enrolled by simple random sampling. Detailed menstrual, obstetric, coital and medical history was obtained. On the third day of the spontaneous cycle, all patients were investigated with a transvaginal scan to assess the number of antral follicles and a fasting venous blood sample was obtained for the measurement of serum AMH and serum basal FSH level.
Results: Basal serum FSH shows a moderately strong negative correlation with antral follicle count (AFC) (r=0.65 p=<0.001) and a strong negative correlation with anti mullerian hormone (AMH) (r=0.69 and p=<0.001). However, the strongest correlation between a biochemical marker and biophysical marker of ovarian reserve is between anti mullerian hormone (AMH) and antral follicle count (AFC) with a very strong positive correlation with a correlation co-efficient r=0.89 (p=<0.001).
Conclusion: Serum AMH best correlates with the antral follicle count. Antral follicle counts although an efficient test to detect ovarian reserve is uncomfortable for the patient as it has to be done during menstrual flow. Serum AMH with minimal intracycle and intercycle variation is a more convenient marker to assess ovarian reserve while it maintains the accuracy of AFC
Echocardiography changes in hypertensive disorder of pregnancy
No full textBackground: Acute preeclampsia is associated with significantly higher prevalence of asymptomatic global left ventricular (LV) abnormal function and myocardial injury than uneventful pregnancy.
Objective: To evaluate the LV changes in pre-eclamptic women and to compare with normotensive women.
Methods: This study was conducted in the Department of Obstetrics and Gynecology, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar. Two hundred women were in each group: 200 patients with preeclampsia as cases and 200normotensive patients as controls.
Results: The mean LV end-systolic volume (LV ESV) in pre-eclamptic women was 33.45 ± 2.8, LV end-diastolic volume (LV EDV) was 106 ± 3.01, and LV systolic mass (LV Ms) was 87.1 ± 1.65 when compared to normotensive women LV ESV 27 ± 0.74, (P < 0.0001) LV EDV 106.2 ± 0.43, (P -0.3528), and LV Ms 84 ± 0.56 (P < 0.0001).
Conclusion: This study emphasizes the importance of identifying this subset of preeclamptic patients with echo changes who are at higher risk of developing cardiovascular complications later in life by undergoing echocardiography
