67 research outputs found
Bio-chemical characterization and in silico computational experimental properties of Trianthema triquetra Rottler & Willd.: A desert medicinal plant for industrial products
No full textThis research work prospects the phytochemical and biological properties of different polarity solvent (methanol, ethyl-acetate, n-hexane, and n-butanol) extracts of Trianthema triquetra Rottler & Willd. The assessment of chemical profile was done by ascertaining total bioactive contents and UHPLC-MS analysis. Similarly, biological profile was analyzed via determination of antioxidant (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum and metal chelation) and key enzyme inhibition (acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, and tyrosinase) potential. Principal component analysis (PCA) was also conducted to highlight the correlation amongst bioactive contents and tested bioassays. The highest proportion of total phenolic (59.85 mg GAE/g extract) and flavonoid (19.85 mg RE/g extract) contents were exhibited by methanol extract which might be correlated with its higher antioxidant capacity. Similarly, UHPLC-MS phytochemical profiling of the methanol extract unveiled the identification of 26 secondary metabolites belonging to phenolic, flavonoids, glucoside, coumarin, alkaloid, and fatty acid derivatives. The ethyl-acetate fraction exhibited the highest inhibition against BChE, α-amylase and α-glucosidase, while the n-butanol and n-hexane extracts were found to be the active against AChE and tyrosinase enzymes and the molecular docking studies explained the possible mechanism of enzyme inhibition. Results of antioxidant assays were further confirmed by PCA analysis, which shows highly effective association amid total bioactive contents and antioxidant assays
THE CONTEMPT POWER: A SWORD OR A SHIELD? – A STUDY OF THE LAW AND PRACTICE OF CONTEMPT OF COURT IN MALAYSIA.
No full textThe issue relating to contempt of court has caught the attention of people from all walks of life in Malaysia, particularly, after the controversial incidents of the removal of Tun Salleh Abbas, the then Lord President, in 1988 and the dismissal of the former Deputy Prime Minister, Dato’ Seri Anwar Ibrahim, in 1998. The judiciary is attacked and its independence is questioned. The lawyers are placed under the threat of contempt proceedings when they tried to exercise their right to freedom of speech and expression and to exercise their duty to act for their clients without fear or favour. The Bar feels that the right to freedom of speech and expression is infringed. The Bar perceives that the contempt power was being misused by the judges.
The Malaysian law of contempt of court is derived from the English common law tradition and is characterised by substantial flexibility. This flexibility results in variable approaches and perceptions by judges that leave uncertainties in this area of law. Consequently, a draft of Contempt of Court Act 1999 has been proposed to the Malaysian government with the main intention of overcoming uncertainties in the law. Placing the comprehensive rules in a statute will allow easier access to and greater clarity of the law because all the rules and procedures would be found in one piece of legislation.
This thesis aims to state and explain the law and the practice of contempt of court in Malaysia. This study will examine the anomalies that derived from the substantial flexibility approaches by the judges in this area of law. Thorough examination and analysis would help identifying the problems and dilemma and the way that the draft Contempt of Court Act 1999 could provide remedies for the predicaments. To illuminate the understanding of the actual practical problem, this study incorporates in-depth interviews together with questionnaire surveys. A total of 15 in-depth interviews have been conducted among the Malaysian judicial officers, advocates and prosecutors. This is further complemented by postal questionnaires sent to these selected legal actors chosen at random in accordance with their seniority, aiming at eliciting their knowledge and opinion on the subject matter at hand. The combinations of theoretical discussion on contempt of court, together with the empirical study, have proved to yield a valuable insight into the re-evaluation of the Malaysian law and practice of contempt of court.
This research reveals that the uncertainties in the law of contempt of court in Malaysia were ‘caused’ by the inconsistencies in the application and approaches by the judges. The judges have unfettered discretion in determining contempt cases. The majority of the Malaysian legal actors support the idea of placing the law of contempt in a piece of legislation in order to overcome these arbitrariness and uncertainties. They hold that to have credence, the law of contempt would have to be well-defined, as in the absence of any clear guidelines it would be unmerited to imprison anyone for contempt
RELATIONSHIP OF HIGH TRIGLYCERIDE AND CHOLESTEROL LEVEL IN PATIENTS WITH HYPERTENSION, DIABETES AND CEREBROVASCULAR ACCIDENTS
No full textAim: To assess the prevalence of high cholesterol and triglycerides in patients with diabetes, hypertension and stroke.
Place and Duration: In the Medicine department of Govt General Hospital, Ghulam Muhammad Abad, Faisalabad for one-year duration from January 2019 to January 2020.
Methods: A total of 150 patients were selected from the medicine department after randomized sampling technique.
Results: Isolated stroke was found in 93 (62%) of 150 patients and isolated diabetes in 57 (38%). Isolated hypertension was found in 21(7%), 6(2%) patients showed combined hypertension, CVA and diabetes mellitus. Combined hypertension and stroke were observed in 18 (6%) patients. Diabetes and hypertension were combined in 20 (6.7%) patients, and diabetes and stroke in 7 (2.3%) patients.
Key words: diabetes, hypertension, stroke
Folio
No full textPlatinum EditionGod Bless Them! pp. 1; In Memory of Prof. Khurshid A. Gill. pp. 2; Sandhu, M. Y.-Poetry-Memories of the Bye-gones. pp. 2; Arif Qureshi-In dulcet memory... pp. 3-4; Arif Qureshi-Poetry-Reminiscences. pp. 4; Ravia Shabeen-The Folio (Registering its History). pp. 5-6; Folio (Year by Year). pp. 7-8; Interview-The Living Legend (F.E. Chaudhry is the oldest Formanite alive, to the best of our knowledge). pp. 9-10; Interview-An Hour with Mian Muhammad Somroo. pp. 11-12; Zainab Mohsin-Buildings. pp. 13-14; Agha Mohsin Sohail-Formanites Are Great. pp. 15-17; Once A Formanite... Always A Formanite. pp. 18-20; Haque Nawaz Cheema-Love for my Institution. pp. 21; Agha Saeed-Old is Gold, New is Silver. pp. 22; Lamia Islam Khan-My Favourite Place. pp. 23; Sara Kanwal-Motivation Forever. pp. 24-25; Bilkis Hussain-Before Sunset. pp. 26; Farid A. Malik-Back to 1958. pp. 27-28; The Excellers. pp. 29-30; Position Holders (Convocation 2008). pp. 31; Survey. pp. 33-34; Donald Alfred Smith-Poetry-A Valentine. pp. 35; Easha Farooq-Love - A Human Need. pp. 36; Fatima Majeed-Defining Love. pp. 37; Bahawal Shehryar-A Fundamentalist. pp. 38; Farhat Aziz-Essay-Concept of Love in Christianity and Islam. pp. 39-40; Fatima Tahir-Mother's Love. pp. 41; Rabiya Khawar-A Blessing for the Two Worlds. pp. 42; Anam Khalid-Etymology of Love. pp. 43; Noor Nisha-Beauty of Love. pp. 44; Ayesha Rana-The Ultimate Aim. pp. 45; Madiha Sundas Rana-I Love thee for a Heart that is Kind. pp. 46; Rabiya Khawar-True Love Never Dies. pp. 47; Amina Jamil-Love - A Timeless Essence. pp. 48; Farhan Hashmi-Love Its Immortal. pp. 49; Kashifa Khalid-A Quest. pp. 50; Daud Aziz Khokher-Love!!! pp. 51-52; Bilkis Hussain-The Truth about Love!!! pp. 53; Alvi, M. 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Furqan-Poetry-Examinations. pp. 108; Prof. Arif Qureshi-Poetry-Dreams. pp. 109; Sheraz Ashraf-Poetry-Lonely Heart. pp. 109; Easha Farooq-Poetry-Winter's Tale. pp. 110; Sana Alvi-Poetry-After She Left Me. pp. 110; Sandhu, M. Y.-Poetry-She comes Not. pp. 111; Erum George-Poetry-Change. pp. 111; Muhammad Adeel-Poetry-Peace. pp. 112; Adeel Anwar-Poetry-Vengeance. pp. 112; Azzam Saddique-A ""Prefect"" Story. pp. 113-114; Muhammad Adeel-Flirtation. pp. 115; Saad Sarfraz-Misery Loves Company. pp. 116-117; Haider F. Halim-No Donkeys in New York. pp. 118-119; Lamia Islam Khan-How to prepare a Bride? pp. 120; Saba Zareen-Modern Love Letter. pp. 121; Lamia Islam Khan-Load Shedding. pp. 122; Zafar Khattak-Application to the Staff Editor. pp. 123; Augustine, Milcah-Cartoons. pp. 124-126; Riaz Akbar Somairi-Article-Prospects of Peace in Multicultural South Asia. pp. 127-128; Bakhtawar Khan-Caste System. pp. 129-130; Abdur Rehman Farrukh-Women are not born. They are made. pp. 131-132; Fraaz Mehmud-Romanticism as a Pillar of Nationalism. pp. 133-134; Fizza Ali Shah-Is mobile phone use among youngsters really a menace? pp. 135-136; Mehreen Ali Kasana-One Muffled Scream. pp. 137-138; Kamal ud Din-Dr. Kamal ud Din. pp. 139-140; Miss Zara Hussain. pp. 141; Miss Saima Saleem. pp. 142; Beenish Khokhar-Unforgettable Tour. pp. 143-144; Rizwan Kamran-The Teacher. pp. 145; Maryam Azhar-IT: A New, Challenging Dimension. pp. 146-148; Folio [Urdu] 148 p.Editorial Board (English). 2 pages before Editorial; Advisory Board. 1 page before Editorial; Prof. Khurshid A. Gill & Mr Perviaz Rehmatullah. page 1; F. E. Chaudhry. after page 10; Mian Muhammad Somroo. before page 11; Society Presidents. before page 29; Political Cartoons created by Javed Iqbal (Famous Cartoonist). on 2 pages, after page 79; 20 pages of pictures, Memories, Commencement 2008: Convocation, Valedictory 2009, Sports Day, Line Work, The Story of Yester Years, People Who Make Difference, Campus Life, Societies, Drama. after page 148; Folio Team with Prof Dr K. K. Aziz. after page 8 (Urdu side); Editorial Board (Urdu). 1 page before Urdu Content
NEEDLE STICK AND SHARPS INJURIES; FREQUENCY AND THE FACTORS CONTRIBUTING AMONG HEALTH CARE WORKERS OF A TERTIARY CARE PRIVATE HOSPITAL OF LAHORE
No full textA Critical Study of the Novel “Shahr khali, Kucha Khali”: ناول”شہرخالی،کوچہ خالی“ کا تنقیدی مطالعہ
No full text"Shahr Khali Kocha Khali" is a renowned novel written by Mustansar Hussain Tarar, a prominent Pakistani writer and travelogue author. The novel was first published in 1979 and has since become a classic of Pakistani literature. Tarar's writing evokes a sense of nostalgia for a bygone era while also addressing contemporary issues. "Shahr Khali Kocha Khali" is not just a novel but a commentary on urbanization, societal changes, and the complexities of human relationships. It captures the essence of Lahore's history and culture, making it a significant work in Pakistani literature.
Reference:
1. Nasir Kazmi, Bergine, Lahore: Fazl-e-Haq and Sons Darbar Market, 1992, p. 592. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, Lahore: Sang-e-Mail Publications, 2020, p. 1233. Issue, Quarterly Literary Magazine, Karachi: October to December 2013, p. 724. Mumtaz Ahmad Khan, Dr., Urdu Novels After Independence, Karachi: Anjaman Urdu Tragqi Pakistan, 1997, p. 1785. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p. 726. Ibid, p. 257. Ibid, p. 228. Ibid, pp. 27-289. Ibid, pp. 55-5610. Khuram Sohail, interview with Mustansar Hussain Tarar, Dawn News, January 17, 2019.11. Naeem Ahmed, Dr., Sigmund Freud, Theory of Psychoanalysis, Lahore: Negarshat Publishers, 2021, p. 8012. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p. 9013. Ibid, p. 7814. Rubina Shaheen, Ph.D., Psychology and Literary Creativity, Reflections International, Book 28, April 2018, p. 1115. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p. 6516. Ibid, p.8417. Ibid, p. 17618. Khuram Sohail, interview with Mustansar Hussain Tarar, Dawn News, January 17, 2019.19. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p. 11920. Dr. Saleem Akhtar, Psychological Critique, Lahore: Sang-e-Mail Publications, 15 20 A.D., p. 22821. Anwar Jamal, Professor, Literary Terms, Islamabad: National Book Foundation, January 2016, p. 9522. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p. 17123. Ibid, p. 17124. Sultana Bakhsh, Tales and Humor, Islamabad: National Book Foundation, 2012, p. 4025. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p.6826. Mumtaz Ahmad Khan, Dr., Few Important Aspects of Urdu Novel, Karachi: Anjuman Tragqi Urdu Pakistan, 2003, p. 6327. Mustansar Hussain Tarar, Shahr Khali, Kocha Khali, p.7
Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjogren's syndrome
No full textObjectives: To assess non-invasive imaging for detection and quantification of gland structure, inflammation and function in patients with primary Sjogren's syndrome (pSS) using PET-CT with 11C-Methionine (11C-MET; radiolabelled amino acid), and 18F-fluorodeoxyglucose (18F-FDG; glucose uptake marker), to assess protein synthesis and inflammation, respectively; multiparametric MRI evaluated salivary gland structural and physiological changes. /
Methods: In this imaging/clinical/histology comparative study (GSK study 203818; NCT02899377) patients with pSS and age- and sex-matched healthy volunteers underwent MRI of the salivary glands and 11C-MET PET-CT. Patients also underwent 18F-FDG PET-CT and labial salivary gland biopsies. Clinical and biomarker assessments were performed. Primary endpoints were semi-quantitative parameters of 11C-MET and 18F-FDG uptake in submandibular and parotid salivary glands and quantitative MRI measures of structure and inflammation. Clinical and minor salivary gland histological parameter correlations were explored. /
Results: Twelve patients with pSS and 13 healthy volunteers were included. Lower 11C-MET uptake in parotid, submandibular and lacrimal glands, lower submandibular gland volume, higher MRI fat fraction, and lower pure diffusion in parotid and submandibular glands were observed in patients vs healthy volunteer, consistent with reduced synthetic function. Disease duration correlated positively with fat fraction and negatively with 11C-MET and 18F-FDG uptake, consistent with impaired function, inflammation and fatty replacement over time. Lacrimal gland 11C-MET uptake positively correlated with tear flow in patients, and parotid gland 18F-FDG uptake positively correlated with salivary gland CD20+ B-cell infiltration. /
Conclusion: Molecular imaging and MRI may be useful tools to non-invasively assess loss of glandular function, increased glandular inflammation and fat accumulation in pSS
L.): Substantial Yield Losses, Practical Achievements, Improvement Approaches, and Adaptive Mechanisms
No full textIstihsan (juristic preference) : the forgotten principle of Islamic law
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
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