33 research outputs found
High Lift Split Flaps for the Flying-V
No full textThe Flying-V, a novel aircraft design developed at Delft University of Technology, presents a revolutionary flying wing transport aircraft with a remarkable 20% reduction in energy consumption compared to traditional twin-aisle planes. This thesis project delves into the study of optimizing the Flying-V's landing performance, emphasizing the necessity of reducing pitch attitude. High-lift devices, particularly split flaps, were explored for this purpose. Wind tunnel tests were carried out on a scaled-down model of the half- wing, in the Open Jet Facility of TU Delft. The tests yielded two successful flap configurations— a single-flap and a double-flap. These were analyzed further using a flight performance tool to make a final selection on the flap configuration. The single-flap option proved effective in reducing landing pitch attitude by 3 degrees, significantly lowering obscured segment by 20 to 30 m and the pilot's eye altitude by 1 m. This is a quite desirable outcome for the landing performance of the Flying-V which significantly improves pilot’s vision.Flying-VAerospace Engineerin
Contributions to arachnid systematics in honor of Willis J. Gertsch, on the occasion of his seventy-fifth birthday. Bulletin of the AMNH ; v. 170, article 1
Get PDF270 p., [1] leaf of plates : ill. (some col.), maps, ports. ; 26 cm."Scientific publications of Willis J. Gertsch": p. 11-14.Includes bibliographical references and author index.A new species of Mastigoproctus (Thelyphonidae), the first record of Uropygida from Costa Rica / Carlos E. Valerio -- On the Cryptocellus centralis group (Arachnida, Ricinulei) / Norman I. Platnick and Mohammad U. Shadab -- A new genus of troglobitic scorpion from Mexico (Chactoidea, Megacorminae) / Oscar F. Francke -- A new Bothriurus from Bolivia (Scorpiones, Bothriuridae) / Emilio A. Maury -- A study of the syntypes of Diplocentrus keyserlingii (Diplocentridae) / Herbert L. Stahnke -- On Liphistius desultor Schiödte (Araneae, Liphistiidae) / John A. Murphy and Norman I. Platnick -- Three new mygalomorph spiders (Dipluridae, Masteriinae) from Colombia / Robert J. Raven -- The mygalomorph spider genus Microhexura (Araneae, Dipluridae) / Frederick A. Coyle -- Two new species of the mygalomorph spider genus Neocteniza (Araneae, Actinopodidae) / Norman I. Platnick and Mohammad U. Shadab -- Spitting spiders (Araneae, Scytodidae, Scytodes) from Central America / Carlos E. Valerio -- Studies on the Pholcidae. 1, Notes on the genera Artema and Physocyclus / Paolo Marcello Brignoli -- A new genus of spider (Agelenidae) from California exhibiting a third type of leg autospasy / Vincent D. Roth -- Classification of two North American species of Pirata, with a description of a new genus (Araneae, Lycosidae) / Charles D. Dondale and James H. Redner -- Studies on species of Holarctic Pardosa groups (Araneae, Lycosidae). 2, Redescriptions of Pardosa modica (Blackwall), Pardosa labradorensis (Thorell), and Pardosa sinistra (Thorell) / Torbjörn Kronestedt -- A revision of the nigra group of the genus Pardosa in North America (Araneae, Lycosidae) / Donald C. Lowrie and Charles D. Dondale -- The Neotropical spider genera Architis and Staberius (Pisauridae) / James E. Carico -- A new species of Trechalea (Pisauridae) from North America / James E. Carico and Edwin W. Minch -- The Ctenidae of temperate zone North America / William B. Peck -- Color variation in two species of Castianeira (Araneae, Clubionidae) / Jonathan Reiskind -- A new genus of the spider family Gnaphosidae (Arachnida, Araneae) / Norman I. Platnick and Mohammad U. Shadab -- On the spider genus Eilica (Araneae, Gnaphosidae) / Norman I. Platnick and Mohammad U. Shadab -- New species and records of Neotropical Gnaphosidae (Arachnida, Araneae) / Norman I. Platnick and Mohammad U. Shadab -- A revision of the genus Habrocestum (Araneae, Salticidae) in North America / David B. Richman -- A revision of the spider genus Paradamoetas (Araneae, Salticidae) / Bruce Cutler -- Three new species of Salticidae (Araneae) / María Elena Galiano -- New Central and South American Uloboridae (Arachnida, Araneae) / Brent D. Opell -- The Nearctic species of Oreonetides (Araneae, Linyphiidae) / P.J. Van Helsdingen -- The erigonine spiders of North America. Part 5, The genus Satilatlas (Araneae, Linyphiidae) / A.F. Millidge -- More on the genus Araneus from North America / Herbert W. Levi -- Structure of the male palpal organ in Mimetus, Ero, and Gelanor (Araneae, Mimetidae) / William A. Shear -- A textricellid spider from Chile (Araneae, Textricellidae) / Raymond R. Forster and Norman I. Platnick
Comparative Analysis of Horizontal and Vertical Etched Fiber Bragg Sensor for Refractive Index Sensing
No full textAdvanced supervised machine learning methods for precise diabetes mellitus prediction using feature selection
Get PDFBackgroundDiabetes mellitus (DM) is a chronic metabolic disorder that poses a significant global health challenge, affecting millions, many of whom remain undiagnosed in the early stages. If left untreated, diabetes can result in severe complications such as blindness, stroke, cancer, joint pain, and kidney failure. Accurate and early prediction is critical for timely intervention. Recent advancements in machine learning techniques (MLT) have shown promising potential in enhancing disease prediction due to their robust pattern recognition and classification capabilities.Materials and methodsThis study presents a comparative analysis of supervised MLT such as Support Vector Machine (SVM), Naïve Bayes (NB), K-Nearest Neighbors (KNN), and Random Forest (RF) using the Pima Indian Diabetes dataset (PIDD) from the UCI repository. A 10-fold cross-validation approach was employed to mitigate class imbalance and ensure generalizability. Performance was evaluated using standard classification metrics: accuracy, precision, recall, and F1-score.ResultsAmong the evaluated models, SVM outperformed the others with an accuracy of 91.5%, followed by RF (90%), KNN (89%), and NB (83%). The study highlights the effectiveness of SVM in early diabetes prediction and demonstrates how model performance varies with algorithm selection.ConclusionUnlike many prior studies that focus on a single algorithm or overlook validation robustness, this research offers a comprehensive comparison of popular classifiers and emphasizes the value of cross-validation in medical prediction tasks. The proposed framework advances the field by identifying optimal models for real-world diabetes risk assessment
Sensitivity analysis of a square shape apodize fibre Bragg grating chemical sensor assisted by high refractive index bi-directional coupler on both sides
No full textEvaluation of Hypolipidemic and Hepatoprotective Effects of Ethanolic Extract of Cleome Brachycarpa on Albino Rabbits
No full textPhylogenetic analysis of HDV isolates from HBsAg positive patients in Karachi, Pakistan
No full textAbstract Background In spite of a high occurrence of Hepatitis Delta in the province of Sindh in Pakistan, no genetic study of Hepatitis Delta virus (HDV) isolates from this region was carried out. The aim of this study is to analyze the genetic proximity within local HDV strains, and relationship with other clades of HDV, using phylogenetic analysis. Results Phylogenetic analysis of nucleotide sequences of the Hepatitis Delta Antigen (HDAg) R0 region obtained in this study, showed considerable diversity among the local strains with a potential subgroup formation within clade I. The multiple sequence alignment of predicted amino acids within clade I showed many uncommon amino acid substitutions within some conserved regions that are crucial for replication and assembly of HDV. Conclusions The studied strains showed a range of genetic diversity within HDV clade I. There is clustering of sequences into more than one group, along with formation of potential subgroup within clade I. Clustering shows the genetic closeness of strains and indicates a common origin of spread of HDV infection. Further phylogeny-based studies may provide more information about subgroup formation within clade I and may be used as an effective tool in checking and/or preventing the spread of hepatitis D virus infection in this region.</p
Design of a Reliable Bi-objective Relief Routing Network in the Earthquake Response Phase
No full textAbstractOne of the most critical issues in areas which have recently faced natural disasters is transportation of both injured people to medical centers and relief commodities to their desired destinations. In such situation, due to disruptions, some routes may lose all or part of their capacities and not be able to accept as much vehicles as before. Consequently, the relief vehicles face difficulties to follow their itinerary. Such critical circumstance calls for finding reliable solutions. This study develops a new bi-objective, multi-mode and multi-commodity model, in which the reliability is taken into account to help managers in making more reliable decisions. To solve this model, the TH method is used in order to find the equivalent single objective model and this new model is exactly solved by coding in GAMS software
Reticulon 3 Regulates VLDL Secretion by Controlling VTV Biogenesis
Get PDFSecretion of very low-density lipoprotein (VLDL) by the liver is an important physiological process; however, the rate of VLDL secretion is determined by its transport from the ER to the Golgi. This transport event is facilitated by a specialized ER-derived vesicle, the VLDL transport vesicle (VTV). We have reported earlier a detailed VTV proteome which revealed that reticulon 3 (RTN3) is uniquely present in the VTV. Our immunoblotting and electron microscopic data demonstrate that RTN3 is enriched in the VTV; however, other ER-derived vesicles do not contain RTN3. Co-immunoprecipitation data coupled with confocal microscopic analyses strongly suggest that RTN3 interacts with VLDL core protein, apoB100 at the ER level. Our data show that either blocking of RTN3 using specific antibodies or RTN3 knockdown resulted in significant reduction in VTV biogenesis from hepatic ER membranes. Additionally, VLDL secretion from hepatocytes was significantly decreased when RTN3 was silenced by RTN3 siRNA. We conclude that RTN3 regulates VLDL secretion by controlling VTV-mediated ER-to-Golgi transport of nascent VLDL.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
A Decade in Blockchain: A Bibliometric Reflection on the Growth and Interdisciplinary Reach of a Disruptive Technology
Get PDFThis study seeks to deliver a comprehensive bibliometric analysis of blockchain research undertaken from 2013 to 2023. It seeks to map the field’s evolution, highlight emerging trends, and identify key contributors and thematic areas. Understanding these aspects is crucial for guiding future research and policymaking in the rapidly growing domain of blockchain technology. The study utilises a systematic bibliometric analysis approach and the Scopus database was used for collecting data. The analysis includes keyword trends, citation patterns, author productivity, and network analysis. The results reveal significant expansion and diversification in blockchain research, with 13,369 publications and 52,009 contributing authors. Key metrics include a total citation count of 266,483 and an average of 19.93 citations per paper, underscoring the field’s scholarly impact. The study identifies core research themes such as smart contracts, security, IoT integration, and emerging topics like AI and sustainability. The findings highlight the interdisciplinary nature of blockchain research and its global distribution, with notable contributions from China and the United States. The study’s reliance on selected databases and predefined keywords may exclude relevant grey literature and industry reports. Future research should integrate these sources for a more complete view. This study provides a panoramic view of blockchain research, offering valuable insights into its development, current state, and future directions. Identifying key trends, influential contributors, and emerging themes contributes to the academic discourse and supports strategic planning for researchers, practitioners, and policymakers engaged in blockchain technolog
