692 research outputs found
Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review
No full textHigh implantation success following in vitro fertilization cycles are achieved via the
transfer of embryos with the highest developmental competence. Multiple
pregnancies as a result of the transfer of several embryos per cycle accompany with
various complication. Thus, single-embryo transfer (SET) is the preferred practice in
assisted reproductive technique (ART) treatment. In order to improve the pregnancy
rate for SET, embryologists need reliable biomarkers to aid their selection of
embryos with the highest developmental potential. Time-lapse technology is a
noninvasive alternative conventional microscopic assessment. It provides
uninterrupted and continues the survey of embryo development to transfer day.
Today, there are four time-lapse systems that are commercially available for ART
centers. In world and Iran, the first time lapse babies were born in 2010 and 2015,
respectively, conceived by SET. Here, we review the use of time-lapse monitoring in
the observation of embryogenesis as well as its role in SET. Although, the findings
from our review support common use of time-lapse monitoring in ART centers; but,
future large studies assessing this system in well-designed trials are necessary
sj-pdf-3-smo-10.1177_20503121231220216 – Supplemental material for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life?
No full textSupplemental material, sj-pdf-3-smo-10.1177_20503121231220216 for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life? by Azam Biderafsh, Abbas Rahimi foroushani and Saharnaz Nedjat in SAGE Open Medicine</p
sj-pdf-2-smo-10.1177_20503121231220216 – Supplemental material for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life?
No full textSupplemental material, sj-pdf-2-smo-10.1177_20503121231220216 for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life? by Azam Biderafsh, Abbas Rahimi foroushani and Saharnaz Nedjat in SAGE Open Medicine</p
sj-docx-1-smo-10.1177_20503121231220216 – Supplemental material for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life?
No full textSupplemental material, sj-docx-1-smo-10.1177_20503121231220216 for Does adult socioeconomic status mediate the relationship between adolescent socioeconomic status and adult quality of life? by Azam Biderafsh, Abbas Rahimi foroushani and Saharnaz Nedjat in SAGE Open Medicine</p
Efficacy of the in vitro splitting of human preimplantation embryos from ART programs
No full textThe aim of this study was to evaluate the efficiency of in vitro embryo splitting (IES) procedures. We also assessed the
quality of the blastocysts developed from embryos obtained from different sources
Human cumulus cell sensitivity to vitrification, an ultrastructural study
No full textCumulus cells (CCs) play an important role in the regulation of female gamete development, meiotic maturation, oocyte-sperm interaction, capacitation and acrosome reaction. However, their role in maintaining oocyte competence after vitrification is unclear as controversial data on their protecting action against oocyte cryoinjuries are available. Here we described the effects of vitrification on the ultrastructure of human CCs collected from women undergoing assisted reproductive technologies (ARTs). In total, 50 patches of CCs, sampled from high-quality human cumulus-oocyte complexes, were randomly allocated into two groups after patient informed consent: 1, fresh CCs (controls, n = 25); 2, vitrified CCs (n = 25). Samples were then prepared and observed by transmission electron microscopy. In fresh CCs, in which small cell clusters were visible, cell membranes were joined by focal gap junctions. Microvilli were rare and short. Nuclei, mitochondria, smooth endoplasmic reticulum (SER), Golgi apparatus and lipid droplets appeared well preserved; vacuoles were scarce. After vitrification, we observed two populations of CCs: light CCs, with a smooth appearance and few short microvilli; and dark CCs, with numerous and long microvilli. In both, most of the organelles appeared similar to those of fresh CCs. Lipid droplets were denser and more numerous, with respect to fresh CCs. They were mainly located in the peri-nuclear and sub-plasmalemmal regions. Numerous packed electron-negative vacuoles were visible. The vitrification procedure did not cause alterations in the fine structure of major organelles, except for an increased amount of lipid droplets and vacuoles. This specific sensitivity of human CCs to vitrification should be considered during ARTs
Impact of different embryo loading techniques on pregnancy rates in in vitro fertlizaton/embryo transfer cycles
No full textBackground: Embryo transfer (ET) technique is one of the important factors of in vitro fertlization success. Among the different steps in ET technique, less attention has been given to embryo loading (EL). The aim was to compare the impact of two different techniques of EL on pregnancy rate in IVF/ET cycles. Materials and Methods: In this retrospective study, 144 and 170 patients were placed in groups A and B, respectively. In Group A, the embryos were drawn directly into the ET catheter from culture microdrop under the oil. In Group B, the embryos were transferred from culture microdrop into G2 medium in center-well dish. Then, the embryos were drawn into the catheter and finally transferred into the uterus. Both groups were adjusted for other parameters based on the EL technique. The main outcome measure was pregnancy rate. Results: There were insignificant differences for etiology of infertility, source of sperm, type of stimulation protocol, percent of IVF or intracytoplasmic sperm injection type of ET catheter, cycles with good quality embryos and transferred embryos between two groups. The rate of both chemical and clinical pregnancy was higher in Group B compared to A, but the difference was insignificant (P = 0.09 and P = 0.1, respectively). Conclusion: It seems that there is no difference in the outcome by loading the embryo from microdrop or center-well dish
Agha Shahid Ali, 18th Annual ODU Literary Festival
No full textPoet Agha Shahid Ali teaches in the M.F.A. Creative Writing Program at the University of Massachusetts, Amherst. His six collections of poetry include A Nostalgist’s Map of America, The Half Inch Himalayas, A Walk Through the Yellow Pages and The Beloved Witness: Selected Poems. He has also translated The Rebel’s Silhouette, a selection of poems by Faiz Ahmed Faiz as well as the author of T. S. Eliot as Editor. His poems appear regularly in journals such as Antioch Review, Chelsea, Denver Quarterly, Field, Grand Street, Paris Review Poetry, TriQuarterly and Yale Review. He has won fellowships from the Pennsylvania Council on the Arts, the Ingram-Merril Foundation, the Bread Loaf Writers’ Conference and the New York Foundation for the Art. His recent — as yet uncollected — poems focus on the current turmoil in Kashmir, where he is from originally and where he spends his summers
Ecriture au feminin par procuration : Pierre de patience d'Atiq Rahimi
No full textThe author proposes a feminist interpretation of Pierre de patience, a novel by the afghan francophone writer Atiq Rahimi. He sees it as a francophone text come from elsewhere, as world literature, but also as a message and hope for our time and for gender equality
THE LURE OF THE IMAGE KEBOHONGAN PADA NARASI PEREMPUAN DALAM SYNGUE SABOUR PIERRE DE PATIENCE KARYA ATIQ RAHIMI
No full textThis study aims to determine the position of the author in women narration. With Rahimi’s background as a feminist, he said that with his novel he voiced the voices of Afghan women. Rahimi offered a strong female figure in the middle of the patriarchal shackles who is able to fight the system. The problem of this study is Rahimi’s ambiguity in narrating women. To determine the position of the author, the research uses the concept of the lure of the image belongs to Lidia Curti. The lure of the image is an offer provided by the author to give positions to women that are in fact not provided by them. Based on the research conducted, the results show that Rahimi keeps women as objects in a patriarchal world. In this case he is not able to pull the women out of the patriarchal zone. The space given to women by Rahimi reinforces male power. What Rahimi written in this novel is the lure of the image according to Curti’s concept which explains it as an image of women given by author or known as female gaze
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