1,690 research outputs found
Spatial Analysis in Veterans Cemetery Location
Get PDFThe National Cemetery Administration of the U.S. Department of Veterans Affairs has funded a relatively large number of new national and state veterans cemeteries in recent years to meet the burial needs of a growing number of aging veterans. This paper examines the history of this agency and the evolving role that spatial analysis has played in identifying appropriate locations for new cemeteries. It also examines some of the spatial assumptions used in cemetery planning and tests these assumptions in Virginia. Data from two Virginia state veterans cemeteries are examined to determine appropriate veterans cemetery service area boundaries. Finally, a location-allocation model is used to determine the best locations for a new veterans cemetery in Virginia.cemetery; veterans; location
A COMPARISON OF INPUT-OUTPUT MODELS:GHOSH REDUCES TO LEONTIEF (BUT 'CLOSING' GHOSH MAKES IT MORE PLAUSIBLE)
Get PDFGhosh's model is discussed in this paper under two alternative scenarios. In an open version we compare it with Leontief's model and prove that they reduce to each other under some specific productive conditions. We then move onto reconsidering Ghosh's model alleged implausibility and we do so reformulating the model to incorporate a closure rule. The closure solves, to some extent, the implausibility problem very clearly put out by Oosterhaven for then value-added is correctly computed and responsive to allocation changes resulting from supply shocks.Multi-sectoral Input-Output Models, Market Economy, Planned Economy.
Coordination induced fluorescence enhancement and construction of a Zn3 constellation through hydrolysis of ligand imine arms
No full textThe phenoxido and alkoxido bridged neutral Zn3 complex [Zn3(mu-H2bemp)2(m3-emp)2](1), with an angular Zn3(mu-OPh)2(mu-OEt)2 core and capping nitrogen donors, was synthesized via simultaneous chelation-cum-bridging of the parent and hydrolysed ligands. Zinc(II) coordination triggered the
solution phase imine (C=N) bond hydrolysis of H3bemp (2,6-bis-[(2-hydroxyethylimino)methyl]-4-methylphenol) and yielded the unexpected angular trinuclear Zn(II) complex 1, having structural
similarity with the Zn3 active site of P1 nuclease. H3bemp also displays a zinc(II) selective chelation-enhanced fluorescence response from strong metal ion coordination. Complexation of zinc(II) with H3bpmp (2,6-bis-[(3-hydroxypropylimino)methyl]-4-methylphenol), a close analogue of H3bemp,instead provides only mononuclear [Zn(H2bpmpHN)2](ClO4)2·2H2O(2·2H2O) (HN is the proton attached to an imine nitrogen atom) of two zwitterionic ligands, generated through a kind of coordination driven acid–base reaction, without showing any aggregation reaction. As the sole metal–organic precursor, both the complexes under pyrolytic conditions give ZnO nano structures of two morphologies
Meeting the Memorial Needs of Virginia Veterans: An Analysis of Existing and Proposed Cemetery Sites
Get PDFThis report evaluates the burial needs of Virginia's veterans. It describes the locations and capacities of cemeteries that serve veterans who reside in Virginia, evaluates the need for additional burial capacity, identifies an optimal location for a new state cemetery, and examines the issues to consider in procuring additional property for cemetery expansion. It also investigates the role of cost and marketing/outreach efforts in shaping veteran burial choices and the potential effect of expanding interment eligibility to out-of-state residents.cemetery; location; veterans
Cell-penetrating protein-recognizing polymeric nanoparticles through dynamic covalent chemistry and double imprinting
Get PDFMolecular recognition of proteins is key to their biological functions and processes such as protein–protein interactions (PPIs). The large binding interface involved and an often relatively flat binding surface make the development of selective protein-binding materials extremely challenging. A general method is reported in this work to construct protein-binding polymeric nanoparticles from cross-linked surfactant micelles. Preparation involves first dynamic covalent chemistry that encodes signature surface lysines on a protein template. A double molecular imprinting procedure fixes the binding groups on the nanoparticle for these lysine groups, meanwhile creating a binding interface complementary to the protein in size, shape, and distribution of acidic groups on the surface. These water-soluble nanoparticles possess excellent specificities for target proteins and sufficient affinities to inhibit natural PPIs such as those between cytochrome c (Cytc) and cytochrome c oxidase (CcO). With the ability to enter cells through a combination of energy-dependent and -independent pathways, they intervene apoptosis by inhibiting the PPI between Cytc and the apoptotic protease activating factor-1 (APAF1). Generality of the preparation and the excellent molecular recognition of the materials have the potential to make them powerful tools to probe protein functions in vitro and in cellulo.This article is published as Ghosh, Avijit, Mansi Sharma, and Yan Zhao. "Cell-penetrating protein-recognizing polymeric nanoparticles through dynamic covalent chemistry and double imprinting." Nature Communications 15, no. 1 (2024): 3731. doi: https://doi.org/10.1038/s41467-024-48131-5
Ghosh, the shadow lines, and the Indian-English novel
No full textThe prizewinning author of novels, nonfiction, and hybrid texts, Amitav Ghosh grew up in India and trained as an anthropologist. His works have been translated in over thirty languages. They cross and mix a number of genres, from science fiction to the historical novel, incorporating ethnohistory and travelogue and even recuperating dead languages. His subjects include climate change, postcolonial identities, translocation, migration, oceanic spaces, and the human interface with the environment
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