1,723,553 research outputs found

    Aven and Survivin Expression in Egyptian Acute Leukemia and Their Relation to Apoptosis

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    Background: Several anti apoptotic signals have been recently identified. Aven and Survivin are broadly expressed and are conserved in mammalian species. Patients and Methods: 39 AML and 25 ALL were tested. Aven and Survivin expression were detected by RT-PCR. DNA fragmentation was carried out daily after treatment..Results: Survivin was expressed (P=0.06) more in AML (74%) than in ALL (52%). While, Aven was equally expressed in both leukemias. Patients were categorized into 3 groups based on DNA fragmentation. Absence of Aven significantly (p‹0.001) contributed to DNA fragmentation,but Survivin did not contribute as much. None of the concordant both positive Survivin and Aven were in group III (the good 5 day fragmentation, (P< 0.001). Survivin was statistically related to CD7 expression (P<0.001) in AML only. There was a significant dissociation between Aven and Survivin in AML (p=0.03) and near significant dissociation in ALL (p=0.07). Conclusion: Aven seems to be more important as an inhibitor of apoptosis than survivin in acute leukemia. The presence of both confers a survival disadvantage and a significantly worse DNA fragmentation pattern suggesting a synergistic inhibition of apoptosis. The highly significant relation between CD7 and survivin expression might suggest their involvement in a common signal transduction pathway

    Yves de Kerouallan (1895-1984) ombres et lumières en Bretagne ; [exposition, Musée de Pont-Aven, 29 janvier-22 mai 2011]

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    Catalogue de l'exposition présentée au Musée de Pont-Aven du 29 janvier au 22 mai 2011. Après la dernière exposition " Yves de Kerouallan ", du vivant de l'artiste, en 1984 à Redon, le Musée de Pont-Aven souhaite faire découvrir ce peintre en Finistère. L'exposition, dont le présent catalogue rend compte, vise à montrer comment Yves de Kerouallan, influencé par l'École de Pont-Aven, a exprimé la rudesse du travail de la mer, les processions et pardons de Bretagne par l'intermédiaire d'un trait épais, de compositions très structurées, de grands personnages. Tantôt lumineux, tantôt plongés dans la pénombre, ses sujets sont rehaussés de touches vives conférant une grande singularité à sa peintur

    Pont-Aven

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    Pont Aven, Brittany, Franc

    Post box - Pont-Aven

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    Pont Aven, Brittany, Franc

    Shop Pont-Aven

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    Pont Aven, Brittany, Franc

    Pont-Aven Mill

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    Pont Aven, Brittany, Franc

    Pont-Aven thatched house

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    Pont Aven, Brittany, Franc

    water-aven

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    water-avenAt and in the running waters are . . . water-aven or chocolate root, Geum Rivale . . . .PRINTED ITEM W. J. KIRWIN MAY 1972JH MAY 1972Not usedNot usedWithdraw
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