8,065 research outputs found

    Liquidity risks

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    Recent credit crises have demonstrated that liquidity is a fundamental cause of economic shocks, say Anthony Asher, Simon Webb and Andrew Doughman, who suggest that actuaries can play a vital role in finding solutions for liquidity risk.This is an edited extract of a paper that was prepared for the Institute of Actuaries of Australias (Institute) 4th Financial Services Forum 2008

    The Diagnosis and Management of Malignant Gliomas

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    iv, 59 p.The treatment of malignant gliomas remains one of the great challenges in clinical medicine. The most aggressive form of malignant glioma is glioblastoma multiforme (GBM), which is also the most prevalent primary central nervous system tumor. Many investigator initiated studies related to the treatment of malignant gliomas are currently underway in this country and throughout the world. One organization conducting such research is Carolina Neurosurgery and Spine Associates in Charlotte, North Carolina, the nation's largest community-based neurosurgical group. Dr. Anthony L. Asher, MD, FACS directs a research staff at CNSA that is presently involved in numerous clinical trials related to brain tumors and other neurosurgical disorders. During a ten-week internship under the guidance of Dr. Asher, I became involved in an ongoing investigator initiated study designed to assess the efficacy of a combination of therapies in the treatment of malignant gliomas. This study used temozolomide as a neoadjuvant treatment with chemo-radiotherapy and Gliadel ® (BCNU) wafers. In addition to assisting with data collection related to this study, I was involved in other activities during this experience including independent research, observation during procedures, and participation in patient care conferences. What follows is a summary of malignant gliomas treatment options associated with these tumors, an overview of clinical trials and a detailed description of the protocol, Temozolomide as Neoadiuvant and Chemoradiotherapy Following Resection and GLIADEL® Wafer Placement in Patients with Newly Diagnosed High-grade Glioma. Additional concepts that were explored during this internship, in addition to and other work-related experiences, are detailed in the SIP journal.Carolina Neurosurgery and Spine Associates. Charlotte, North Carolina

    Prospective Clinical Trials

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    ii, 50 p.Properly designed and executed clinical trials are the best-known mechanism by which the safety and efficacy of new treatments and competing strategies can be evaluated. In the United States, numerous individuals and institutions are involved in the design and implementation of clinical trials. Although much of clinical research is performed in traditional academic settings, a significant amount of research is now being conducted through community-based medical centers. Carolina Neurosurgery and Spine Associates (CNSA) is one of the nation's largest community-based neurosurgical groups. The physicians of CNSA conduct a variety of clinical trials related to neurosurgical diseases and a number of those trials were active during a ten week internship under the guidance of Anthony L. Asher MD F.A.C.S. One of the group's most complex trials involves the administration of a recombinant immunotoxin known as hIL13-PE38QQR (IL-13 PE) to brain tumor patients. IL13-PE has been shown to possess specific anti-tumor activity against a variety of cell lines, including malignant primary brain tumors. This protocol, like other research studies involving human subjects, is conducted according strict moral and ethical principles defined over the last 60 years by international convention. While working under Dr. Asher, an intimate understanding of the basic aspects of clinical research was established. The following composition is intended to provide a summary of the most essential concepts assimilated during this internship. Specifically, an outline of the basic scientific, regulatory and ethical principles that currently guide clinical research efforts is presented here. Additionally, a summary of the IL-13 protocol is offered as a practical example of how research studies are implemented.Carolina Neurosurgery and Spine Associates. Charlotte, North Carolina

    Michel Asher : Shoot to Kill. A Soldier's Journey through Violence ; James Adams, Robin Morgan & Anthony Bambridge, Ambush. The War between the SAS and the IRA

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    Deutsch Richard. Michel Asher : Shoot to Kill. A Soldier's Journey through Violence ; James Adams, Robin Morgan & Anthony Bambridge, Ambush. The War between the SAS and the IRA. In: Études irlandaises, n°17-2, 1992. pp. 260-262

    Interview with Anthony F. Janson

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    Anthony F. Janson is a retired professor and former Department Chair for the UNCW Department of Art and Theatre [retired December 2002]. This interview covers his complete life and career. He discusses his relationship with his art historian father, H.W. Janson, including his relationship as son and co-author and editor of the Janson texts on art history. The interview covers Tony's career as a scholar, book editor, author, art museum curator [at Indianapolis Art Museum and North Carolina Art Museum], and as a professor. Throughout, he comments on important artists in history and his philosophy of art history. He also includes stories of his time in the Vietnam War

    Interview with Anthony F. Janson

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    Anthony F. Janson is a retired professor and former Department Chair for the UNCW Department of Art and Theatre [retired December 2002]. This interview covers his complete life and career. He discusses his relationship with his art historian father, H.W. Janson, including his relationship as son and co-author and editor of the Janson texts on art history. The interview covers Tony's career as a scholar, book editor, author, art museum curator [at Indianapolis Art Museum and North Carolina Art Museum], and as a professor. Throughout, he comments on important artists in history and his philosophy of art history. He also includes stories of his time in the Vietnam War

    Family Assessment- Author Index

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    Author Index (12 pages) A-Z A Abbott, D.: 263 Abery, B.: 242 Abidin, R: 81, 265 Abramovitch, R: 134, 135, 136, 137, 139,142,143,144,145,146 Abril, s.: 118 Achenbach, T. M.: 12,47, 118, 223, 265 Acock, A. c.: 206 Adams, G. R: 205 Adams, S. J.: 226 Al-Khayyal, M.: 74 Alexander, J. F.: 75 Allisson, P. D.: 185 Alwin, D. F.: 182,191,194 Amato, P. R: 205- 231, 206, 207, 210, 213,215,216, 219, 221, 222, 224, 227,230 Ammerman, R : 263 Amoloza, T. 0 .: 170, 171,172,176, 179, 187, 188 Anastasi, A.: 265 Anderson, B. J.: 85 Anderson, c.: 117 Anderson, P. P.: 104 Anderson, S. A.: 79, 168, 177 Anthony, J.: 117 Apley, J.: 84 Aponte, H. J.: 117 Appelbaum, M.: 263 Arrington, A.: 11 Asher, S.: 82 Asterita, M. F. : 92 Attneave, c.: 121 Auslander, W. F: 85 Z Zane, N .: 107, 119 Zetlin, A.: 263 Zill, N.: 83 Zuo, J.: 171, 180, 18

    Family Assessment- Author Index

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    Author Index (12 pages) A-Z A Abbott, D.: 263 Abery, B.: 242 Abidin, R: 81, 265 Abramovitch, R: 134, 135, 136, 137, 139,142,143,144,145,146 Abril, s.: 118 Achenbach, T. M.: 12,47, 118, 223, 265 Acock, A. c.: 206 Adams, G. R: 205 Adams, S. J.: 226 Al-Khayyal, M.: 74 Alexander, J. F.: 75 Allisson, P. D.: 185 Alwin, D. F.: 182,191,194 Amato, P. R: 205- 231, 206, 207, 210, 213,215,216, 219, 221, 222, 224, 227,230 Ammerman, R : 263 Amoloza, T. 0 .: 170, 171,172,176, 179, 187, 188 Anastasi, A.: 265 Anderson, B. J.: 85 Anderson, c.: 117 Anderson, P. P.: 104 Anderson, S. A.: 79, 168, 177 Anthony, J.: 117 Apley, J.: 84 Aponte, H. J.: 117 Appelbaum, M.: 263 Arrington, A.: 11 Asher, S.: 82 Asterita, M. F. : 92 Attneave, c.: 121 Auslander, W. F: 85 Z Zane, N .: 107, 119 Zetlin, A.: 263 Zill, N.: 83 Zuo, J.: 171, 180, 18

    Letter from Anthony Brummelkamp to Mrs. G. Groen van Prinsterer

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    In a letter to Mrs. G. Groen van Prinsterer from Rev. Anthony Brummelkamp, the author is clearing up some statements of Rev. Budding and chiding Rev. Hendrik Scholte for having an arrogant and sharp tone. A foonote to the letter mentions the school operated by Rev. Brummelkamp and Rev. Albertus C. Van Raalte in Arnhem.https://digitalcommons.hope.edu/vrp_1840s/1193/thumbnail.jp

    Fr. Anthony J. Gittins, C.S.Sp.

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    Fr. Anthony J. Gittins, C.S.Sp. [b. 1943] was ordained in 1967. He attended the University of Edinburgh from 1968-72 and received a doctorate in Social Anthropology in 1977. Fr. Gittins was a missionary to the Mende people in Sierra Leone from 1972-80. He went on to serve as a professor at the Missionary Institute and as Formation Director in London from 1980-84. He is the Emeritus Professor of Theology and Culture at the Catholic Theological Union in Chicago, Illinois, where he began teaching in 1984. Fr. Gittins has spent over thirty years ministering to homeless women and those leaving prostitution in Chicago, and is the author of several books.https://dsc.duq.edu/sohp/1000/thumbnail.jp
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