1,721,042 research outputs found
Hopes, disillusions and more hopes from vitamin C
No full textIn the current view of most biochemists and physiologists, the role of L-ascorbic acid (AA) in cell metabolism would be more or less confined to the scavenging of reactive oxygen species. Nevertheless, many data have been collected in our and other laboratories concerning the involvement of AA in many different aspects of cell metabolism. At the present time the molecular sites of action of AA have not been completely elucidated, but recent findings on the specific requirement of AA for the activity of several 2-oxoacid-dependent dioxygenases involved in cell signalling and the activation of transcription factors open new fascinating perspectives for further research
The role of ascorbic acid in cell metabolism: between gene-directed functions and unpredictable chemical reactions
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Preliminary data on the ascorbate system in gametophytes of Brachytecium velutinum and Marchantia polymorpha.
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Identification and analysis of proteins sharing dehydroascorbate reductase activity
No full textDehydroascorbate (DHA)-reducing proteins were observed using a native-PAGE/activity staining method, and identified in soybean and rice by Western analysis using antibodies against homologous proteins known to catalyse DHA reduction. Administration of 1 mM DHA apparently did not trigger DHA reductase activity in lupin and onion, whereas activity was increased in rice and barle
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