130,614 research outputs found
Arsenura armida
No full textArsenura armida (Cramer, 1779). Phalaena Attacus armida Cramer, 1779: 6, pl. 197, fig. A. Arsenura armida armida – Draudt 1930: 792. DÉTERMINATION. — Morphologique. Moléculaire (BOLD: ABY 7651, ACE 5265, ACF 4386, ACF 4389). LOCALITÉ TYPE. — Suriname (Cramer 1779). RÉPARTITION GÉOGRAPHIQUE. — Guyano-amazonienne (Brechlin & Meister 2010b). REMARQUE TAXONOMIQUE. — Le statut d’ Arsenura armida interrogeait Lemaire à cause de l’hétérogénéité phénotypique des exemplaires de ce taxon. Dans une tentative de clarification, Lemaire (1980) définit trois formes d’habitus pour les mâles (forme alaire + coloration), reconnaissant que « ces disparités suggèrent que l’on est en présence d’un complexe de plusieurs espèces et sous-espèces mais cette hypothèse est difficile à concilier avec l’existence, dans certaines zones, de populations intermédiaires et surtout avec l’inorganisation apparente de la répartition qui comporte la présence de populations phénotypiquement identiques dans plusieurs régions différentes, géographiquement isolées » (Lemaire 1980: 29). Le concept “armida” a depuis été décliné grâce à son analyse génétique, dans sa gigantesque aire de répartition (du Mexique au nord-est de l’Argentine, sensu Lemaire 1980) en trois espèces distribuées schématiquement ainsi: 1) A. armida (Cramer, 1779) (localité type: Suriname) dans le nord et l’est de l’Amérique du Sud; 2) A. fuscata Brechlin & Meister, 2010 (localité type: Pérou) dans l’ouest de l’Amérique du Sud; et 3) A. arianae Brechlin & Meister, 2010 (localité type: Mexique) en Amérique centrale. Mais pour autant, la variabilité phénotypique de Arsenura armida se retrouve chez ces espèces qui produisent des formes comparables. Ce type de polymorphisme concerne quelques Lépidoptères dont en Guyane Telchin licus (Drury, 1773) (Castniidae Boisduval, 1828) (Miller 1986, 1995; González 2003; Bénéluz & Gallard 2012). DISTRIBUTION EN GUYANE. — Connu des trois zones biogéographiques. HABITAT EN GUYANE. — Forêts primaire et secondaire, savane. MATÉRIEL DU MITARAKA EXAMINÉ. — Guyane • 1 ♂; Maripasoula, Mitaraka, DZ Coulé-Coulé ou Inselberg; 2°43’30”N, 54°47’30”W ou 2°27’30”N, 54°53’W; 21.X.2004 ou 28.X-2.XI.2004; J.-P. Champenois leg.; collecte mélangée; Coll. BH (no. Ars0011) • 1 ♂; Maripasoula, Mitaraka, Borne 1; alt. 670 m; 2°08’N, 54°25’W; 19-26.IX.2006; J.-P. Champenois leg.; Coll. BH (no. Ars0013) • 1 ♂; Maripasoula, Mitaraka, Crique Alama (DZ); alt. 310 m; 2°14’1.9”N, 54°27’38.1”W; La Planète revisitée, MNHN / PNI Guyane; APA-973-1; 23.II-26.III.2015; E. Poirier leg.; MNHN • 1 ♂; mêmes données que précédent; Coll. FB • 3 ♂; Maripasoula, Mitaraka, Crique Alama (DZ); alt. 310 m; 2°14’1.9”N, 54°27’38.1”W; La Planète revisitée, MNHN / PNI Guyane; autorisation APA-973-2; 11-21.VIII.2015; FB leg.; MNHN • 3 ♂; mêmes données que précédent; Coll. FB.Published as part of Bénéluz, Frédéric, 2021, Liste commentée des Saturniidae (Lepidoptera, Bombycoidea) de Guyane, avec la liste des taxons récoltés au Mitaraka (extrême sud-ouest guyanais), pp. 759-809 in Zoosystema 43 (31) on page 762, DOI: 10.5252/zoosystema2021v43a31, http://zenodo.org/record/579681
MET overexpression and gene amplification in NSCLC: a clinical perspective
No full textLorenza Landi, Gabriele Minuti, Armida D'Incecco, Jessica Salvini, Federico CappuzzoMedical Oncology Department, Istituto Toscano Tumori, Ospedale Civile, Livorno, ItalyAbstract: The transmembrane tyrosine kinase mesenchymal-epidermal transition (MET) receptor and its ligand, hepatocyte growth factor, also known as scatter factor, have recently been identified as novel promising targets in several human malignancies, including non-small cell lung cancer (NSCLC). Amplification, mutation, or overexpression of the MET gene can result in aberrant activation of the MET axis, leading to migration, invasion, proliferation, metastasis, and neoangiogenesis of cancer cells, suggesting that interfering with the MET/hepatocyte growth factor pathway could represent a potential antitumor strategy. While the role of MET mutations in NSCLC is not as yet fully understood, retrospective studies have shown that an increased MET gene copy number is a negative prognostic factor. In NSCLC, amplification of the MET gene is a relatively rare event, occurring in approximately 4% of patients not previously exposed to systemic therapies and in up to 20% of patients with acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors. In preclinical models, the presence of MET amplification is a predictor of high sensitivity to anti-MET compounds, and several agents have entered in clinical trials for patients having advanced disease, with promising results. The aim of the present review is to summarize available data on the role of MET in NSCLC and to describe therapeutic strategies under investigation.Keywords: mesenchymal-epidermal transition, hepatocyte growth factor, epidermal growth factor receptor, non-small cell lung cance
Luoghi, paesaggi e giardini nel racconto di Rinaldo e Armida tra letteratura e arti figurative
No full textIl saggio analizza i rapporti tra il testo della Gerusalemme Liberata (XIV canto) in relazione all'iconografia dei dipinti raffiguranti gli Amori di Rinaldo e Armida soprattutto nella pittura del Seicento e del Settecent
Una rassegna bibliografica ragionata
No full textGuida ragionata ai contributi scientifici sul Terzo Settore. Attraverso una categorizzazione dei contributi si tenta di fornire una lettura diacronica del fenomeno del Volontariato nel Mezzogiorno d'Itali
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Scelte scolastiche e famiglie
No full textOggetto del presente lavoro sono le scelte di investimento scolastico e formativo nel passaggio dalla scuola media inferiore alla superiore, considerate come esito di un processo che combina le chances educative del quartiere di residenza con l'influenza dell'ambiente familiare. Nell'ambito di una ricerca svolta in sei scuole medie inferiori ubicate nel territorio di Bari, le scelte scolastiche sono considerate in connessione ai concetti di capitale sociale familiare e di habitus. Viene messo in evidenza il supporto familiare al percorso scolastico del ragazzo, come pure gli attegiamenti, che, riguardo alla scuola, la famiglia mette in campo
CEEG mapping in drug-free schizophrenics. Differences from healthy subjects and changes induced by haloperidol treatment
No full text
QEEG alpha 1 changes after a single dose of high-potency neuroleptics as a predictor of short-term response to treatment in schizophrenic patients
No full text
- …
