4,308 research outputs found
Medical cannabis and driving
No full textMedical cannabis use is increasingly common in Australia. Patients and physicians need to be aware of the important implications that such use may have for driving. Objective The aim of this article is to briefly review the scientific evidence regarding cannabis and driving impairment and discuss current legal issues affecting patients, as well as to update physicians on relevant issues and the best guidance to offer their patients. Discussion Delta-9-tetrahydrocannabinol (THC) impairs driving performance and can increase crash risk. These effects are more pronounced in people who use THC occasionally and can last for up to eight hours with oral THC products. There is no evidence that cannabidiol (CBD) impairs driving. Patients using THC-containing products should avoid driving and other safety-sensitive tasks (eg operating machinery), particularly during initiation of treatment and in the hours immediately following each dose. Patients may test positive for THC even if they do not feel impaired, and medical cannabis use does not currently exempt patients from mobile (roadside) drug testing and associated legal sanctions.Full Tex
Assessment of the statistical relevance of TR-PIV datasets
No full textThe increasing interest for high repetition rate global optical measurement techniques such as Time-Resolved Particle Image Velocimetry (TR-PIV) raises a number of questions concerning their ability to provide relevant statistical and spectral quantities. In an effort to address this issue, complementary TR-PIV and Laser Doppler Velocimetry (LDV) measurements have been carried out. An application to the analysis of the detached flow over a NACA 0015 airfoil at a Reynolds number Re=105 in a water tunnel is proposed
Are blood and oral fluid Δ9-tetrahydrocannabinol (THC) and metabolite concentrations related to impairment? A meta-regression analysis
No full textBlood and oral fluid Δ9-tetrahydrocannabinol (THC) concentrations are often used to identify cannabis-impaired drivers. We used meta-analytic techniques to characterise the relationships between biomarkers of cannabis use, subjective intoxication, and impairment of driving and driving-related cognitive skills. Twenty-eight publications and 822 driving-related outcomes were reviewed. Each outcome was measured in concert with one or more biomarkers of cannabis/THC use and/or subjective intoxication. Higher blood THC and 11−OH-THC concentrations, oral fluid THC concentrations and subjective ratings of intoxication were associated with greater impairment in ‘other’ (mostly occasional) cannabis users (p's0.10), although the analyses were less robust. Blood and oral fluid THC concentrations are relatively poor indicators of cannabis/THC-induced impairment.Full Tex
Kustverdediging na 1990 (Kustnota 1990): Technisch rapport 11: Strand en duinsuppleties
No full textIn Technisch Rapport 11 (TR 11) wordt een overzicht gegeven van de strand- en duinsuppleties, welke ter compensatie van kusterosie zijn uitgevoerd. In 1988 is het "Handboek zandsuppleties" uitgegeven. Hierin is een schat van gegevens verzameld over het desbetreffende onderwerp. Dit rapport voorziet in een aanvulling op het handboek, met meer recente gegevens. Overlapping van dit rapport met het handboek is zoveel mogelijk vermeden. Naast de aanvulling wordt ingegaan op de levensduur van suppleties en wordt een eerste aanzet gegeven om een puur economische afweging te maken tussen zandsuppleties, die nu een belangrijke maatregel bij kustverdediging zijn, en de bouw van strandhoofden, wat in het verleden een belangrijke maatregel geweest is. Zand wordt met grote drijvende werktuigen relatief goedkoop, als zandwatermengsel, verplaatst. Een netto-verplaatsing van 200.000 tot 500.000 kubieke meter zand per werktuig, per werkweek is haalbaar. Naarmate het zand hoger en verder op de oever gebracht wordt nemen de kosten toe.Kustnot
A Preliminary Statistical Investigation into the impact of an N-Gram Analysis Approach based on Word Syntactic Categories toward Text Author Classification
No full textQuantitative analysis of literary style has heretofore utilized semantic elements-word counts. This research attempts to identify quantifiable syntactic elements of style that can be used for author identification. The measurement of syntactic elements utilizes a dictionary with one part of speech per word and looks at phrases delimited by punctuation marks. Different size permutations of words - referred to as grams - are counted within each text. Correlations are measured amongst the gram frequencies of eight texts pertaining to four authors, both contemporary and non-contemporary. The correlations are performed across different gram sizes of words. The same treatment is applied to a target text, the Funeral Elegy text. The approach holds for classifying texts temporally consistently across the various gram sizes. Yet a finer grained investigation is required to certify the authorship of the Funeral Elegy text.
(Also cross-referenced as UMIACS-TR-2000-39, LAMP-TR-046
pmTR database: Population matched (pm) germline allelic variants of T-cell receptor (TR) loci
No full textThe IMGT database profiles the TR germline alleles for all four TR loci (TRA, TRB, TRG and TRD), however, it does not comprise of the information regarding population specificity and allelic frequencies of these germline alleles. The specificity of allelic variants to different human populations can, however, be a rich source of information when studying the genetic basis of population-specific immune responses in disease and in vaccination. Therefore, we meticulously identified true germline alleles enriched with complete TR allele sequences and their frequencies across 26 different human populations, profiled by “1000 Genomes data”. We identified 205 TRAV, 249 TRBV, 16 TRGV and 5 TRDV germline alleles supported by at least four haplotypes. The diversity of germline allelic variants in the TR loci is the highest in Africans, while the majority of the Non-African alleles are specific to the Asian populations, suggesting a diverse profile of TR germline alleles in different human populations. Interestingly, the alleles in the IMGT database are frequent and common across all five super-populations. We believe that this new set of germline TR sequences represents a valuable new resource which we have made available through the new population-matched TR (pmTR) database, accessible via https://pmtrig.lumc.nl/.Pattern Recognition and Bioinformatic
RO(S1)-graded TR-groups of Fp, Z and ℓ
No full textAbstractWe give an algorithm for calculating the RO(S1)-graded TR-groups of Fp, completing the calculation started by the second author. We also calculate the RO(S1)-graded TR-groups of Z with mod p coefficients and of the Adams summand ℓ of connective complex K-theory with V(1)-coefficients. These calculations are used elsewhere to compute the algebraic K-theory of certain Z-algebras
Response to: ‘Cannabis use before safety sensitive work: What delay is prudent?’
No full textWe read with interest the commentary by Beckson et al., 2020 on our recent publication, entitled: ‘Determining the magnitude and duration of acute Δ9-tetrahydrocannabinol (Δ9-THC)-induced driving and cognitive impairment: A systematic and meta-analytic review’ (McCartney et al., 2021).Full Tex
Development of Interpersonal Mindfulness Scale-TR (IMS-TR): A Validity and Reliability Study
No full textThe purpose of this study is to develop an Interpersonal Mindfulness Scale-TR (IMS-TR) for Turkish culture. For the data collection process, four different sample groups participated in the study. To test the construct validity of the scale an exploratory factor analysis was performed. Results suggested a 13-item, two-factor solution as (1) awareness and (2) being in the moment. Two-factor structure explains 50.65% of the variance. A confirmatory factor analysis results showed good fit for two-factor solution. The Mindfulness in Parenting Questionnaire and the Mindfulness in Marriage Scale were used to examine a convergent validity and positive significant relationships were found between the scales. To test the reliability of the scale Cronbach's Alpha reliability coefficient of the overall scale was determined to be .826. To determine the stability coefficient of the IMS-TR, test-retest method was used and according to result there is a positive relationship between the scales. According to all of these results, it can be said that the IMS-TR has a validity and reliability. © 2020 The Author(s
Building a culture of research: Using undergraduate research to advance the TR profession, build research capacity, and foster collaborative relationships
No full textThe purpose of this paper is to provide a rationale for rethinking the role of undergraduate research and to describe Douglas College's innovative approach to developing a research culture through fostering undergraduate therapeutic recreation (TR) students' research skills. In the literature review we. build the case for an undergraduate research-based curriculum as an essential step in building a research culture. A research skills development framework (Willison & O'Regan, 2007) is presented as a way to view research skills and to understand how a student might progress and develop research competence. The role of collaboration is examined as an intimate and essential aspect of building a research culture. We present the initiatives and ideas that Douglas College has used in its quest to create a research ethos that embraces not only the TR Department but also the TR community, and conclude by outlining future steps to continue the work at Douglas, including reaching out to other educational institutions to collaborate on research projects. ABSTRACT FROM AUTHORPeer reviewedFinal article published.undergraduate researchTherapeutic recreationResearch Skills Development Frameworkresearch cultureeducationcurriculumcommunity-based researc
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