1,721,926 research outputs found
Renal dysplasia in grey Alpine breed cattle unrelated to CLDN16 mutations
Get PDFRENAL dysplasia (RD) is a developmental disorder of the renal parenchyma characterised by anomalous differentiation of the nephrons and collecting ducts (Woolf and others 2004). In human medicine, RD is one of the principal causes of childhood end-stage renal failure. In veterinary medicine, it has been described in several species, including cattle (Dunham and others 1989, Simon and others 1999, Ohba and others 2001, Castro and others 2007, Maxie and Newman 2007, Aresu and others 2009, Philbey and others 2009). In Japanese Black cattle, RD shows autosomal recessive inheritance, caused by CLDN16 mutations (Hirano and others 2000, Ohba and others 2000, Hirano and others 2002). These mutations affect one of the members of the claudin family of genes which plays an important role in the formation of tight junctions in the kidney (Simon and others 1999). In Japanese Black cattle, RD is classified into two types, according to two independent CLDN16 mutations (Hirano and others 2002), but no morphological or histopathological differences between the two types have been reported. This short communication deals with a case of RD in twin grey Alpine heifers which are not related to mutations of the CLDN16 gene
AResU-Net: Attention Residual U-Net for Brain Tumor Segmentation
No full textAutomatic segmentation of brain tumors from magnetic resonance imaging (MRI) is a challenging task due to the uneven, irregular and unstructured size and shape of tumors. Recently, brain tumor segmentation methods based on the symmetric U-Net architecture have achieved favorable performance. Meanwhile, the effectiveness of enhancing local responses for feature extraction and restoration has also been shown in recent works, which may encourage the better performance of the brain tumor segmentation problem. Inspired by this, we try to introduce the attention mechanism into the existing U-Net architecture to explore the effects of local important responses on this task. More specifically, we propose an end-to-end 2D brain tumor segmentation network, i.e., attention residual U-Net (AResU-Net), which simultaneously embeds attention mechanism and residual units into U-Net for the further performance improvement of brain tumor segmentation. AResU-Net adds a series of attention units among corresponding down-sampling and up-sampling processes, and it adaptively rescales features to effectively enhance local responses of down-sampling residual features utilized for the feature recovery of the following up-sampling process. We extensively evaluate AResU-Net on two MRI brain tumor segmentation benchmarks of BraTS 2017 and BraTS 2018 datasets. Experiment results illustrate that the proposed AResU-Net outperforms its baselines and achieves comparable performance with typical brain tumor segmentation methods
Las vitaminas liposolubles y su toxicidad: MItos y creencias de los suplementos vitaminicos
No full textCódigo de proyecto: GNH 11001Amalia Aresu Garcia-Obregon; director de proyecto: Cristina Naranjo OrtizCurso 2011-2012Grado en Nutrición Humana y Dietética (GNH)Facultad de Ciencias de la Salu
Su Apocolocyntosis 6,1: Marti(s) municipem vides
Get PDFThis paper aims at suggesting a new solution to one of the many Apocolocyntosis’ loci difficiles (6,1). After providing a list of the main solutions advanced throughout the history of the exegesis of the text, it eventually suggests a new one, taking into consideration the palaeographic evidence and the historical and cultural context in which the Apocolocyntosis is supposed to have been written.Lo scopo di questo contributo è di offrire una nuova soluzione a uno dei tanti loci difficiles dell’Apocolocyntosis (6,1). Dopo una lista delle principali soluzioni proposte nella storia dell’esegesi del testo, questa nota ne suggerisce infine una nuova, tenendo in considerazione l’evidenza paleografica e il contesto storico-culturale nel quale si ritiene che l’Apocolocyntosis sia stata scritta
High energy irradiated protoplanetary disks:the X-rays and FUV role in thermo-chemical modeling
Get PDFIn de laatste twee decennia hebben sterrenkundigen een enorme hoeveelheid informatie kunnen vergaren over het scenario waarin leven kan ontstaan. Onderzoek naar de vorming van planeten speelt daarin een belangrijke rol. Het proces van stervorming begint in donkere wolken (Dark Clouds) waar gravitationele ineenstorting leidt tot de formatie van een schijf die de ster omgeeft, de zogenaamde circumstellar schijf. Die kan materiaal (gas en stof) bevatten waaruit planeten ontstaan. Er is dan sprake van een protoplanetaire schijf. Giambattista Aresu onderzocht de impact van hoog energetische straling (röntgenstraling en ver-uv) van de centrale ster op de chemische en thermische structuur van dergelijk omringende protoplanetaire schijven
Isomorfismo ed impression management nei grafici sulla performance ambientale, sociale e di governance nei bilanci
No full textThe aim of the paper is to investigate the main determinants of graphical reporting on environmental, social and governance (ESG) performance and to understand whether impression management and institutional perspectives can help to explain the use of these graphs. Previous studies on graphical reporting, both considering consolidated annual reports and stand-alone sustainability reports, have mainly explained the use of graphs through impression management theories, by showing a selective and distorted use of graphs aimed to portray a favourable view of the firm’s performance. Few studies, on the other hand, have supposed that institutional theory might help to explain the use of graphs. To our knowledge, this is the first paper which focuses on graphs related with the firm’s ESG performance, voluntarily added within consolidated annual reports. Eighty European consolidated annual reports have been investigated through a regression analysis, controlling for size, industry and volatility. It is found, in line with impression management, that firms tend to use more graphs on their ESG performance when their overall financial performance is higher, while the specific environmental, social and governance performance does not seem to drive graphical reporting. These findings suggest that: consolidated annual reports give a priority to economic-financial results and firms are driven, in the choice of non-financial indicators’ graphs, by their overall financial performance, rather than by their specific non-financial performance. In line with institutional theory, it is found that firms tend to replicate the choices made by their market leaders, in the use and content of voluntary graphs. This isomorphic behaviour is stronger when firms face a higher economic uncertainty (estimated by “low” financial performance), in line with mimetic isomorphism. The paper contributes to the voluntary disclosure literature by studying graphical reporting with the lenses of impression management and institutional theories. Both perspectives seem helpful to explain discretional graphical reporting strategies and can be jointly analysed. The paper also provides evidence on the different usage of nonfinancial information in consolidated annual reports rather than in stand-alone sustainability reports. It is suggested to annual reports’ readers to be aware that managers use graphs, even those on the firm’s ESG results, opportunistically and replicating the leaders’ previous reporting choices
Graphical reporting in Italian Annual Reports during the financial crisis: impression management or incremental information?
No full textThis paper investigates whether, before and during the global financial crisis, Italian firms have used financial key performance indicators graphs in the annual reports as impression management tools, to portray a more favourable picture of the firm’s performance than is warranted. This study shows that, during the financial crisis, firms have increased the number of graphs and decreased favourable distortions, although graphs continue to be designed inaccurately. The findings could reflect an increased public scrutiny on the firm’s performance, during the financial crisis. As a theoretical implication, this paper contributes to the existent financial reporting literature by showing that graphs are not necessarily used in line with an agency theory-based impression management, which is the dominant perspective to explain the graphs’ usage in the annual reports during periods of performance upturn. Moreover, it shows that the institutional context can affect voluntary disclosure practices at a firm-level. As a practical implication, this study suggests to annual reports’ readers not to necessarily consider managers as self-serving preparers in their graphical reporting strategies. The study also suggests accounting associations, audit firms and other regulatory bodies to create a set of guidelines for a correct graph’s use and design
- …
