1,721,190 research outputs found

    Supplementary_file_1 – Supplemental material for Effect of statin treatment on circulating malondialdehyde concentrations: a systematic review and meta-analysis

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    Supplemental material, Supplementary_file_1 for Effect of statin treatment on circulating malondialdehyde concentrations: a systematic review and meta-analysis by Angelo Zinellu, Panagiotis Paliogiannis, Maria Franca Usai, Ciriaco Carru and Arduino A. Mangoni in Therapeutic Advances in Chronic Disease</p

    Response to Dr. Anderson’s Letter to the Editor: Modafinil and Armodafinil in Human Milk

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    Response to Letter to the EditorCatherine Leggett, Usha Ritchie, Lynn Costi, Corey Borg, David Elliot, Arduino A Mangoni, William M Hagu

    Supp_figure – Supplemental material for Real-world incidence of patient-reported dyspnoea with ticagrelor

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    Supplemental material, Supp_figure for Real-world incidence of patient-reported dyspnoea with ticagrelor by Adaire E. Prosser, Jessica L. Dawson, KethLyn Koo, Karen M. O’Kane, Michael B. Ward, Richard J. Woodman, Arduino A. Mangoni and Cameron J. Phillips in Therapeutic Advances in Drug Safety</p

    Supplemental_Material – Supplemental material for A pilot cohort study of deprescribing for nursing home patients acutely admitted to hospital

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    Supplemental material, Supplemental_Material for A pilot cohort study of deprescribing for nursing home patients acutely admitted to hospital by Patrick Russell, Sara Laubscher, Gregory W. Roberts, Arduino A. Mangoni, Cameron McDonald, Ivanka Hendrix, Udul Hewage, Dirk Hofmann, Sophie Michell, Lauren Taeuber, Richard J. Woodman, Sepehr Shakib, Gregory B. Crawford, John Maddison and Campbell Thompson in Therapeutic Advances in Drug Safety</p

    Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics

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    Available online 6 October 2017Abstract not availableAnjana Radhakutty, Brenda L. Mangelsdorf, Sophie M. Drake, Andrew Rowland, Malcolm D. Smith, Arduino A. Mangoni, Campbell H. Thompson, Morton G. Bur

    Using the multidimensional prognostic index for treatment decisions and monitoring in frail older patients

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    The routine applicability of clinical guidelines and disease-specific end-points in frail older patients is problematic because of the exclusion of this group from clinical trials, their limited life expectancy, the co-existence of multiple disease states and poor functional status, and the presence of complex drug-drug and drug-disease interactions. In this context, the use of patient-centred end-points that include measures of quality of life might be particularly useful for designing tailored treatment strategies, monitor progress and, ultimately, improve outcomes. The multidimensional prognostic index, an objective, quantifiable, and validated scoring system based on core domains of the comprehensive geriatric assessment, might represent an important tool for the development of clinical guidelines that take into account measures of frailty and patientcentred end-points. However, research is warranted to investigate whether this approach leads to more effective and safe management strategies in old age.</jats:p
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