16,915 research outputs found
Comprehensive effects of LVAD speed changes on alveolar gas exchange, sleep ventilatory pattern, and exercise performance
No full textBackground. Increasing left ventricular assist device (LVAD) pump speed according to patients’ activity is a fascinating hypothesis. This paper is an analysis of the short-term effects of LVAD speed increase on cardiopulmonary exercise performance, muscle oxygenation (NIRS), lung diffusion capacity (DLCO and DLNO), and sleep quality.
Methods. We analyzed CPET, DLCO and DLNO, and sleep in 33 Jarvik 2000 LVAD patients. After a maximal cardiopulmonary exercise test (CPET, n=28), patients underwent two maximal CPETs with LVAD speed randomly set at 3 or increased from 3 to 5 during effort (n=15). Then, at LVAD speed randomly set at 2 or 4, we performed: a) constant workload CPETs assessing O2 kinetics, cardiac output (CO), and muscle oxygenation (n=15); b) resting DLCO and DLNO (n=18); c) nocturnal cardiorespiratory monitoring (n=29).
Results. The progressive pump speed increase raised peak VO2 (12.5±2.5 ml/min/kg vs. 11.7±2.8 at speed 3; p=0.001). During constant workload, from speed 2 to 4, CO increased (3.18±0.76 L/min vs. 3.69±0.75, p=0.015, at rest; 5.91±1.31 L/min vs. 6.69±0.99, p=0.014, during exercise), and system efficiency (τ= 65.8±15.1 sec vs. 49.9±14.8, p=0.002) and muscle oxygenation improved. At speed 4, DLCO decreased, and obstructive apneas increased despite a significant apnea/hypopnea index and a reduction of central apneas.
Conclusion. Short-term LVAD speed increase improves exercise performance, CO, O2 kinetics, and muscle oxygenation. However, it deteriorates lung diffusion, and it increases obstructive apneas, likely due to an increase of intrathoracic fluids. Self-adjusting LVAD speed is a fascinating but possibly unsafe option, probably requiring a monitoring of intrathoracic fluids
Anna Maria Ortese: Possibilmente il più innocente. Lettere a Franz Haas 1990-98, a cura di Francesco Rognoni e di Franz Haas. Mergozzo: Sedizioni, 2016
No full textAnna Maria Ortese, Neapel liegt nicht am Meer, übersetzt von Marianne Schneider, mit einem Nachwort von Franz Haas. Berlin: Friedenauer Presse 2019
No full textAn Article About Albertus C. Van Raalte, Author Unknown, Except for Parts Taken from an Article by Anna C. Post
No full textAn article about Albertus C. Van Raalte, author unknown, except for parts taken from an article by Anna C. Post. The author knew first generation persons in the Holland settlement and therefore, the article has some value.https://digitalcommons.hope.edu/vrp_1890s/1012/thumbnail.jp
Cardiopulmonary Exercise Testing in Adult Congenital Heart Disease
No full textRecently, the number of patients with congenital heart diseases reaching adulthood has been progressively increasing in developed countries, and new issues are emerging: the evaluation of their capacity to cope with physical activity and whether this knowledge can be used to optimize medical management. A symptom-limited cardiopulmonary exercise test has proven to be an essential tool, because it can objectively evaluate the functional cardiovascular capacity of these patients, identify the pathological mechanisms of the defect (circulatory failure, shunts, and/or pulmonary hypertension), and help prescribe an individualized rehabilitation program when needed. The common findings on cardiopulmonary exercise testing in patients with congenital heart diseases are a reduced peak VO2, an early anaerobic threshold, a blunted heart rate response, a reduced increase of V-T, and an increased (V)over dot(E)/(V)over dotCO(2). All these measures suggest common pathophysiological abnormalities: (1) a compromised exercise capacity from anomalies affecting the heart, vessels, lungs, or muscles; (2) chronotropic incompetence secondary to cardiac autonomic dysfunction or beta-blockers and antiarrhythmic therapy; and (3) ventilatory inefficiency caused by left-heart failure with pulmonary congestion, pulmonary hypertension, pulmonary obstructive vascular disease, or cachexia. Most of these variables also have prognostic significance. For these patients, cardiopulmonary exercise testing allows evaluation and decisions affecting lifestyle and therapeutic interventions
Ferraù Fenzoni, Adorazione dei pastori, p. 167, n. 10; Simone Cantarini, Agar e l’angelo, p. 171, n. 17; Carlo Cignani, Sant’Andrea apostolo, p. 179, n. 34; San Benedetto, p. 179, n. 35; Benedetto Gennari, San Filippo Neri in adorazione della Madonna con il Bambino, pp. 181-182, n. 38; Francesco Mancini, Il miracolo di san Mauro, pp. 182-183, n. 39.
No full textA.M. Ambrosini Massari ha scritto le schede dei dipinti: Ferraù Fenzoni, Adorazione dei pastori, p. 167, n. 10; Simone Cantarini, Agar e l’angelo, p. 171, n. 17; Carlo Cignani, Sant’Andrea apostolo, p. 179, n. 34; San Benedetto, p. 179, n. 35; Benedetto Gennari, San Filippo Neri in adorazione della Madonna con il Bambino, pp. 181-182, n. 38; Francesco Mancini, Il miracolo di san Mauro, pp. 182-183, n. 39
Richardson, Barbauld, and the construction of an early modern fan club
No full textMPhilMuch has been written about the life and long works of the eighteenth century epistolary novelist, Samuel Richardson, but the prospect of his position as the first celebrity novelist – responsible for courting his own fame as well as initiating his own fan club – has largely been ignored. The body of manuscripts housed at the National Art Library in the Victoria and Albert Museum in London provides the modern scholar with evidence of the skeletal beginnings of an early fan club. This thesis aims to show how these manuscripts were turned into a saleable commodity by the publisher and entrepreneur Richard Phillips, while under the guiding hand of another, slightly later, literary celebrity, Anna Laetitia Barbauld. In order to restore Richardson’s reputation amongst a new nineteenth century audience, Barbauld was required to construct her own idea of him as an eighteenth century celebrity author, and in doing so the insecurities of a self-professed, apparently diffident man, are revealed. Barbauld’s capacious, but heavily edited selection of letters is analyzed in this thesis, providing ample evidence that Richardson’s correspondents were more than just eager letter writers. By using Barbauld’s biography of Richardson this thesis aims to show how she manipulates the genre of life writing in her construction of him.
This thesis offers an alternative reading of how the Richardson manuscripts are viewed, redefining them as not simply a collection of letters, but as a collective entity, deliberately selected and archived as evidence of an early modern fan club, and its celebrity managing director
Selection of work by Anna Gerber
No full textVarious journals and magazines Anna Gerber has contributed to. Anna Gerber is a graphic designer and writer based in London.
She is the author and designer of All Messed Up: Unpredictable Graphics (Laurence King, 2004) and co-editor and co-designer
of Influences: A Lexicon of Contemporary Graphic Design (Die Gestalten Verlag, 2006) with Anja Lutz. She writes regularily for magazines such as Print, Eye, Creative Review, Varoom and Idea Magazine and her work has also been published in shift!, dot dot dot and +rosebud.
She teaches at the London College of Communication on the BA Graphic Design and MA Design Writing Criticism programmes. She has also held workshops and lectures across the U.K. (including Tate Modern and the V&A Museum), as well as in India, the U.S., Australia and Malaysia.
Anna Gerber is currently engaged in research and developing projects relating to sustainability and how it applies to graphic
design as well as exploring contemporary graphic design in India
Erectile Dysfunction in Heart Failure: Correlation with Severity, Exercise Performance, Comorbidities, and Heart Failure Treatment
No full textIntroduction. Erectile dysfunction (ED) is frequent in males with chronic heart failure (HF) with a severe impact on quality of life for many individuals. The correlation of ED with age and HF severity, comorbidity, and treatment is unclear. Aim. We evaluated the correlation between ED and HF severity, treatment, and comorbidity. Methods. One hundred one HF patients aged 10 mL/min/kg. On multivariable analysis, only age, diabetes, use of diuretics, and hemoglobin are related to ED. Apostolo A, Vignati C, Brusoni D, Cattadori G, Contini M, Veglia F, Magri D, Palermo P, Tedesco C, Doria E, Fiorentini C, Montorsi P, and Agostoni P. Erectile dysfunction in heart failure: Correlation with severity, exercise performance, comorbidities, and heart failure treatment. J Sex Med 2009;6:2795-2805
- …
