3,538 research outputs found
Database for: Excavations at Tall Jawa, Jordan: Volume 3, The Iron Age Pottery
No full textThis is a Microsoft Access database of imagery, drawings, and photos accompanying Excavations at Tall Jawa, Jordan: Volume 3, The Iron Age Pottery by P.M. Michèle Daviau. The text and database present a detailed typology of the Iron Age pottery excavated from 1989 to 1995. Together, they represent an in-depth analysis of the forming techniques employed to make each type of vessel from bowls to colanders, cooking pots to pithoi.
The digital archive is a work in progress by the author. The archive currently holds the collection for Excavation Field D. Upon completion, it will include seven collections, each one consisting of a database of diagnostic sherds and vessels as well as the images of these pots as .tiff files. Databases are related to excavation fields and are designed for meaningful searches: A, B, C-east, C-west, A-east (associated with C-west), D and E
IoWoman, March/April 2004, Vol. 34, no. 2
No full textNewsletter for the Iowa Commission on the Status of Wome
IoWoman, March/April 2004, Vol.34, no.2
No full textNewsletter for the Iowa Commission on the Status of Wome
Degradation mechanism of a Golgi-retained distal renal tubular acidosis mutant of the kidney anion exchanger 1 in renal cells
No full textDistal renal tubular acidosis (dRTA) can be caused by mutations in the SLC4A1 gene encoding the anion exchanger 1 (AE1). Both recessive and dominant mutations result in mistrafficking of proteins, preventing them from reaching the basolateral membrane of renal epithelial cells, where their function is needed. In this study, we show that two dRTA mutants are prematurely degraded. Therefore, we investigated the degradation pathway of the kidney AE1 G701D mutant that is retained in the Golgi. Little is known about degradation of nonnative membrane proteins from the Golgi compartments in mammalian cells. We show that the kidney AE1 G701D mutant is polyubiquitylated and degraded by the lysosome and the proteosome. This mutant reaches the plasma membrane, where it is endocytosed and degraded by the lysosome via a mechanism dependent on the peripheral quality control machinery. Furthermore, we show that the function of the mutant is rescued at the cell surface upon inhibition of the lysosome and incubation with a chemical chaperone. We conclude that modulating the peripheral quality control machinery may provide a novel therapeutic option for treatment of patients with dRTA due to a Golgi-retained mutant.Carmen Y. Chu, Jennifer King, Mattia Berrini, Alina C. Rumley, Pirjo M. Apaja, Gergely L. Lukacs, R. Todd Alexander and Emmanuelle Corda
Old Fashioned Ice Cream Social at the U of M, Crookston Features Author Gayla Marty on Wed., Aug. 18, 2010, from 2-4 p.m.
No full textTollefson, Elizabeth. (2010). Old Fashioned Ice Cream Social at the U of M, Crookston Features Author Gayla Marty on Wed., Aug. 18, 2010, from 2-4 p.m.. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/222491
Our Mission and our Values' : an approach to Russian Banks' Communication Strategies
No full textThis paper looks at the mission statements of Russian banks posted on their websites with the aim of identifying recurrent discursive strategies in an intercultural perspective. Starting from the surveyof twenty websites of Russian banks, the author attempts to highlight the linguistic and visual treatment of mission and value statements, where there seems to emergean interesting mix of both "globalized" and local, culture-specific, features
La politica linguistica nei paesi della CSI
No full textThe paper deals with language status and language use in post Soviet Republics. After a brief introduction to Soviet language policy, the author deals with data from the National census, about the number of Russian speakers in these areas in the years 1989-1991 and in 2004-2006. Other data regard the use of Russian language, as opposed to/or in accordance with titular languages, in different social spheres (education, media, institutions)
Author David Halberstam Available for Interviews Tuesday
No full textLegendary journalist and author David Halberstam, who speaks at 7 p.m. Tuesday (April 20) in the Johnson Commons Ballroom, will be available for interviews earlier that afternoon. The media session is set for 3:30 p.m. in the Bondurant Hall lounge, located on the second floor. No advance credentials are required
Reprogramming endo-lysosomal proteostasis disease stress by UBR1- and arginylation-driven endophagy and autophagy protein quality control
No full textProtein quality control (PQC) is a conformational surveillance system critical to maintaining native protein composition in the cell. However, PQC mechanisms at the endo-lysosomal pathway especially toward membrane proteins and during cumulative endo-lysosomal stress are incompletely understood. We recently identified the ubiquitin ligase UBR1 as a PQC E3 ubiquitin-ligase for endosomal and/or cytosolic Ca2+-increase mediated proteostasis disease stress. As a consequence of the endosomal stress and/or cytosolic Ca2+-increase, the QC pathway using selective endosomal autophagy (endophagy) and autophagy was activated for ubiquitinated and arginylated UBR1-SQSTM1/p62 cargoes. In turn, the loss of UBR1, arginylation or both evoke endo-lysosomal pathway stress. Our data suggest that UBR1 with arginylation-dependent endophagy and autophagy is required during proteostasis perturbations and highlight the importance of UBR1 in stress-induced autophagy QC with implications for various human diseases
"Popular author, poet to read at OU"
No full textNews article"One of America's most popular writers will visit OU Friday, Oct. 18. Marge Piercy, award winning author and poet, will read from her poetry at 4 p.m. in 201 Dodge Hall.
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