297 research outputs found
Erratum: Immunogenicity, antigenicity and epitope mapping of Salmonella InvH protein: An in silico study
Full text linkThere was an error in the author list of the published article.
Two authors (T Hashempour, Z Hasanshahi) requested to remove from the authors lists. After obtaining the agreement of the authors and the corresponding author, Editor-in-Chief accept the corrections as listed below.
The correct author list is:
Behzad Dehghani, Iraj Rasooli
We apologize for any inconvenience this may have caused.
Erratum for:
Immunogenicity, antigenicity and epitope mapping of Salmonella InvH protein: An in silico study
B Dehghani, T Hashempour, Z Hasanshahi, I Rasooli
J Curr Biomed Rep. 2020; 1(1): 9-16
Correction to:Value of 2-[18F]FDG-PET/CT in identifying immune-related adverse events in patients with melanoma or non-small cell lung cancer: a systematic scoping review (Clinical and Translational Imaging, (2024), 12, 2, (187-195), 10.1007/s40336-024-00618-3)
No full textIn this article the author name Mohammad Naghavi-Behzad was incorrectly written as Mohammad Naghavi-Bezhad. The original article has been corrected.</p
Optimizing parallel I/O performance of HPC applications
Full text linkParallel I/O is an essential component of modern High Performance Computing (HPC). Obtaining good I/O performance for a broad range of applications on diverse HPC platforms is a major challenge, in part because of complex inter-dependencies between I/O middleware and hardware. The parallel file system and I/O middleware layers all offer optimization parameters that can, in theory, result in better I/O performance. Unfortunately, the right combination of parameters is highly dependent on the application, HPC platform, and problem size/concurrency. Scientific application developers do not have the time or expertise to take on the substantial burden of identifying good parameters for each problem configuration. They resort to using system defaults, a choice that frequently results in poor I/O performance. We expect this problem to be compounded on exascale class machines, which will likely have a deeper software stack with hierarchically arranged hardware resources.
We present a line of solution to this problem containing an autotuning system for optimizing I/O performance, I/O performance modeling, I/O tuning, I/O kernel generation, and I/O patterns. We demonstrate the value of these solution across platforms, applications, and at scale.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2017-12-01The student, Babak Behzad, accepted the attached license on 2015-11-20 at 13:31.The student, Babak Behzad, submitted this Dissertation for approval on 2015-11-20 at 13:45.This Dissertation was approved for publication on 2015-11-23 at 13:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #8816 on 2016-03-02 at 14:06:01Made available in DSpace on 2016-03-02T20:23:36Z (GMT). No. of bitstreams: 4
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Previous issue date: 2015-11-23Embargo set by: Seth Robbins for item 91322
Lift date: 2018-03-02T20:24:31Z
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Competition in dual-channel supply chains: The manufacturers' channel selection
Full text link© 2020 The Author(s) Innovative selling channels have brought about opportunities as well as challenges for upstream manufacturers. The past few years have witnessed both the success and failure of manufacturers with different channel strategies. To explore the rationale of different channel strategies in various contexts, we develop a model to analyze a manufacturer's channel selection decision among three channel strategies, i.e., a direct-channel strategy, a retail-channel strategy, and a dual-channel strategy consisting of both direct and retail channels. The model rests on the channel differentiation in terms of consumers’ channel preferences and operating costs of retail and direct channels. Specifically, we incorporate the action of a competitor and track down its influence on the focal manufacturer's channel preference. Our research clarifies the role of competition in the market and offers insights into the competitive nature of business in real life. Results show that the manufacturer's channel preference depends not only on the channels’ operating costs and consumers’ channel preferences but also on the competitor's channel strategy. We find that symmetric manufacturers can adopt asymmetric strategies as Nash equilibria and also that there are situations where no Nash equilibrium exists. We characterize the Nash equilibria in the channel selection game based on the exogenous parameters of the model
EMU's Decentralized System of Fiscal Policy
Full text linkThis paper reviews the macroeconomic use of national fiscal policy in EMU and examines the rational and scope for a collective insurance system which redistributes income among countries in response to asymmetric cyclical shocks. The analysis of the record of national fiscal policies before and after the adoption of the Maastricht Treaty finds evidence that the quality of fiscal policies has improved in two ways: they are more clearly countercyclical - or less procyclical - and they are more readily used to restore competitiveness than to attempt to boost demand when competitiveness is eroded. These observations suggest that fiscal policy remains a useful instrument. One question is whether it can be augmented - or perhaps substituted for - with a collective insurance system. Collective insurance is one alternative to external borrowing and lending and therefore one way to deal with the concerns that the SGP is meant to address. We examine in more detail two collective insurance systems: tax revenue sharing and unemployment insurance sharing. We find that the earlier is more promising and examine in some detail how it could be set up. It is no panacea, though. Any insurance mechanism entails moral hazard and that moral hazard can, at best, only be mitigated, not eliminated.Economic and Monetary Union, fiscal Key words Economic and Monetary Union, fiscal stabilisation, collective insurance mechanism, Von Hagen,Wyplosz
Attitude Markers in Sports News: A Corpus-based Study of Native and Non-Native Discourse
No full textMartin and White’s (2005) appraisal theory explores the ways through which evaluative use of language expresses the interpersonal meanings in a text. Despite numerous studies using the appraisal framework, there is little research done on the comparison of appraisal resources used by native and non-native English news writers in discourse produced on the same task. A corpus of 1 million each of native and non-native sports news discourse is compiled from (Britain) native and (Pakistani) non-native online English newspapers, to which the appraisal framework is applied in the current study, comparing the ideological positions and evaluative standpoints of native and non-native sports news writers in sports news discourse. A mixed-method design is applied to carry out the sequential explanatory analysis of the data. The findings indicate the substantial variation in the evaluative use of attitudinal resources when used positively and negatively in native and non-native corpora. In general non-native sports, news writers have used significantly higher frequency of positive and negative attitudinal markers as compared to the native news writers. Non-native news writers have used more affect resources while native news writers have used appreciation resources abundantly as compared to affect and judgment resources. Findings offer further variation in the evaluative stance of native and non-native sports news writers that may be used for studying the difference in academic and non-academic writing styles
Attitude Markers in Sports News: A Corpus-based Study of Native and Non-Native Discourse
Full text linkMartin and White‘s (2005) appraisal theory explores the ways through which evaluative use of language expresses the interpersonal meanings in a text. Despite numerous studies using the appraisal framework, there is little research done on the comparison of appraisal resources used by native and non-native English news writers in discourse produced on the same task. A corpus of 1 million each of native and non-native sports news discourse is compiled from (Britain) native and (Pakistani) non-native online English newspapers, to which the appraisal framework is applied in the current study, comparing the ideological positions and evaluative standpoints of native and non-native sports news writers in sports news discourse. A mixed-method design is applied to carry out the sequential explanatory analysis of the data. The findings indicate the substantial variation in the evaluative use of attitudinal resources when used positively and negatively in native and non-native corpora. In general non-native sports,news writers have used significantly higher frequency of positive and negative attitudinal markers as compared to the native news writers. Non-native news writers have used more affect resources while native news writers have used appreciation resources abundantly as compared to affect and judgment resources. Findings offer further variation in the evaluative stance of native and non-native sports news writers that may be used for studying the difference in academic and non-academic writing styles
Cytokine-mediated FOXO3a phosphorylation suppresses FasL expression in hemopoietic cell lines: Investigations of the role of Fas in apoptosis due to cytokine starvation
No full textWe have investigated phosphatidylinositol 3-kinase (PI3K)-dependent survival signalling pathways using several cytokines in three different hemopoietic cell lines, MC/9, FDC-P1, and TF-1. Cytokines caused PI3K- and PKB-dependent phosphorylation of FOXO3a (previously known as FKHRL1) at three distinct sites. Following cytokine withdrawal or PI3K inhibition, both of which are known to lead to apoptosis, there was a loss of FOXO3a phosphorylation, and a resulting increase in forkhead transcriptional activity, along with increased expression of Fas Ligand (FasL), which could be detected at the cell surface. Concurrently, an increase in cell surface expression of Fas was also detected. Despite the presence of both FasL and Fas, there was no detectable evidence that activation of Fas-mediated apoptotic events was contributing to apoptosis resulting from cytokine starvation or inhibition of PI3K activity. Thus, inhibition of FOXO3a activity is mediated by the PI3K–PKB pathway, but regulation of FasL is not the primary means by which cell survival is regulated in cytokine-dependent hemopoietic cells. We were also able to confirm increased expression of known FOXO3a targets, Bim and p27kip1. Together, these results support the conclusion that mitochondrial-mediated signals play the major role in apoptosis of hemopoietic cells due to loss of cytokine signalling. [ABSTRACT FROM AUTHOR]Peer reviewedfinal article publishedCytokineSignal transductionapoptosisTranscription factorProtein kinas
Bilingualism, Monolingualism and Social Health: A Comparative Study Behzad Khedri , Farideh Sadat Momeni Masuole
No full textdimensions in the two groups of students in favor of bilingual students, and the variables such as age, marriage, field of study, socioeconomic status, religious beliefs and communication skills were influential on the social health of both groups. Also, the results of the regression showed that 29% of the influence on the dependent variable of this study was interpreted by the independent variables. In addition, the communication skill is the strongest variable predictor with a rate of 66%. Keyword: Social Health, Social Integration, Students, Language Bilingualism, Monolingualism and Social Health: A Comparative Study Behzad Khedri[1] , Farideh Sadat Momeni Masuole[2] Received: 18/2/2017 Accepted: 30/4/2018 Abstract There are mental influencing factors among students in the educational context such as educational stress, ethnic and cultural contradictions and the existence of political, belief, racial as well as gender discrimination, which can affect various aspects of student life and the health of this stratum, especially their social dimension could be endangered. Regarding the relationship between language, as a fundamental cultural component, and social health which has not been studied in social health research. In other words, the language of different ethnicities can provide unity, integrity, coherence and participation, or can a common language affect health and its social dimension or not? This study aims to answer the mentioned question by investigating bilingual students (ethnicities) and the monolinguals (those who speak only one language). In the following, we intend to explain what factors affect the social health of each group? The method of this study was survey and data was collected through questionnaires. The statistical population is Sanandaj University students and the sample included 384 individuals by the Cochran formula. The results of this study showed that there is a significant difference between the total social health and its [1]. PhD Student of Social Work, AllamehTabatabaiiUniversity, Tehran. (Corresponding Author). [email protected] [2]. Master of Sociology, ShahedUniversity. [email protected]
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