2,123 research outputs found
Myeloproliferative disorders
No full textThe myeloproliferative disorders (MPDs) are a group of pre-leukaemic disorders characterized by proliferation of one or more lineages of the myelo-erythroid series. Unlike the Philadelphia chromosome in chronic myeloid leukaemia, there is no pathognomonic chromosomal abnormality associated with the MPDs. Chromosomal abnormalities are seen in 30–40% of patients with polycythaemia vera (PV) and idiopathic myelofibrosis (IMF) and seem to indicate a poor prognosis. On the other hand, chromosomal abnormalities are rare in essential thrombocythaemia. Consistent acquired changes seen at diagnosis include deletion of the long arm of chromosome 20, del(13q), trisomy 8 and 9 and duplication of parts of 1q. Furthermore del(20q), trisomy 8 and dupl(lq) all arise in multipotent progenitor cells. Molecular mapping of 20q deletions and, to some extent, 13q deletions has identified a number of candidate target genes, although no mutations have yet been found. Finally, translocations associated with the rare 8p11 myeloproliferative syndrome and other atypical myeloproliferative disorders have permitted the identification of a number of novel fusion proteins involving fibroblast growth factor receptor-1
PAPERS AND INSTRUMENTS OF MICHELL, ANTHONY GEORGE MALDON (1870-1959)
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/64955A.G.M. Michell thrust-bearing catalogues; his Company letterheads; G.H. Vasey's lecture on Michell; correspondence on setting up display at Melbourne University Engineering School. Photographs of crankless engines and components (on bench, and fitted to Buick car), and other machinery; crankless engine factory facade and staff (129-131 Greeves Street, Fitzroy). Drawing and measuring instruments (4 boxes); Michell patent viscometer (1 box), medals (e.g. Kernot Medal),(2 boxes); set of standard weights (1 box); Michell's microscope (1 box).113474
Acquisition: [1991.0074] "PAPERS AND INSTRUMENTS OF MICHELL, ANTHONY GEORGE MALDON (1870-1959)
De Bank The Bench
No full textThis book and the accompanying exhibition are the result of a Form Studies exercise held at the Faculty of Architecture at Delft University of Technology (TU Dellt). This practical exercise, entitled 'The Beneh', is part of a second year teaching "Block" (coordinated by Max Risselada) with 'Imaging and Materialisation' as its central theme. The block lasts eight weeks and is part of the basic educational programme at the faculty. It focuses on aspects of industrial (pre)labrication, montage and detailing. The practical study is carried out parallel with the other items of the block, which concentrate on the design of lightweight dwellings and the analysis of design precedents. 'The Bench' was developed and offered by the staff of the Form Studies group, which is part of the Media section. Major themes in the Media programme are Design Visualisation and Presentation. The Form Studies curriculum focuses on aspects of Formal and Spatial Composition. In addition, Form Studies is responsible for the teaching ol three dimensional Modelmaking techniques, which takes place in a well-equipped workshop. In this particular exercise the aspects ol Composition and Modelling come together. As in the previous application, 'The Tabie, as a metaphor lor architecture' , the task that was set was limited and (seemingly) simple: design a bench for the public realm and then 'build' the design in the form of a scale model 1 : 5 or 1 : 10. The students were stimulated to deal with the bench as an architectural object. The ambition of this approach is to confront students with design themes such as function, shape and proportion, but also with qualities and combinations ol materials, logical and expressive detailing and the consequences of 'making'. The idea is that students should continue refining their designs in the realisation phase. For many students, this is an experience approaching that of a first 'realised' project (though of course limited in scope and scale). The exercise, with 'The Bench' as its theme, was offered during 1994 and 1995. The students worked with considerable enthusiasm and the results were varied and, for second-year students, often surprisingly professional. For the Form Studies team this was a reason to organise an exhibition and this publication. We hope you will enjoy the results of the Bench project.ArchitectureArchitectur
Credible Governance? Transparency, Political Control, the Personal Vote and British Quangos
No full textThis article claims that special-purpose independent agencies such as quangos provide an avenue for understanding the 'personal vote' and political control of administrative policy making in Britain. Quangos make policies that directly influence particularistic concerns in an MP's constituency, generating incentives for MPs to meddle with their independence in order to capture the personal vote. A division of labor within the governing party relies on back-bench MPs to sound 'fire alarms' when their constituents find fault with quango activities. Once the alarms are sounded, the government has the incentive to manipulate quangos' independence, for example, by making their decision making transparent to provide information for the fire alarm mechanism in the future. This manipulation draws from the government's stock of political capital gained from a supportive electorate. Statistical analysis of transparency in British executive non-departmental public bodies from 2002 to 2005 suggests that increases in back-bench salience (personal vote) and public satisfaction with government (government strength) increase the transparency by which quangos make decisions, thus decreasing their independence. Public satisfaction with the status quo of public service provision, by contrast, decreases transparency, increasing independence. These results suggest that far from being fully independent, quasi-governmental organizations are subject to political control. © 2008 The Author
Reply to Bench (1973)
No full textThe author is in agreement with Bench 1973 that without specific analysis one cannot be certain that the auditory output from a given loudspeaker matches the input to that speaker. However, issue is taken with Bench concerning the results obtained by Ashton 1971
Designing a landscape bench
No full textThe built landscape that ranges from the paved concrete paths that we walk on to the towering buildings that can rise thousands of feet above. These objects were intentionally designed by people to serve specific functions to benefit us. However, as time moves forward, and we as people change, our designs can become outdated, no longer relevant, or simply not exciting. The landscape bench is one part of the landscape that has struggled to evolve over the years and is limited in the number of functions that it could provide. The landscape bench has been documented for hundreds of years and has served as a place of refuge in the landscape - providing a hub for social interaction, a location to go to, and simply a place to sit. Our current perception and expectations have limited this piece of the landscape to just a place to sit, not allowing for even simple changes to its simple design. Through the design and build process this thesis investigates topics regarding material sustainability, site specific designs, and social interactions in relation to bench design and construction. Through the creation of a prototype and a final model this project created a well researched and designed bench for its site. The process demonstrated that making considerations for history, sustainability and case studies, the landscape bench can be designed and built with meaning and purpose.M.L.A.Includes bibliographical reference
Bench-scale centrifuge testing to determine the hydraulic conductivity of clayey soils
No full textThe purpose of this research is to validate a mathematical model for flow through saturated and unsaturated porous media using a bench-scale centrifuge for an accurate determination of the hydraulic conductivity (function of the saturation degree of a soil) within a limited time at a reasonable price. The aim of this paper is to show preliminary results of this investigation where the validation and calibration of the mathematical model is performed determining the hydraulic conductivity of saturated porous media, such as kaolin clay and glass porous filters, with a bench-scale centrifuge
Utilization of a dumbbell floor press in predicting an estimated 1RM max barbell bench bress using repetitions to fatigue
No full textThis research aims to investigate the relationship between the performance of a dumbbell floor press and the traditional barbell bench press, as a safer alternative means of assessing maximal strength in upper body pressing. The 1 repetition maximum (1RM) test using a Barbell Bench Press (BBP) has been widely used for this purpose but can be time-consuming and poses an increased risk of injury when performed incorrectly, particularly among novice individuals. The most common injuries associated with the bench press are anterior glenohumeral instability, atraumatic osteolysis of the distal clavicle, and pectoralis major rupture. Alternative protocols for estimating 1RM, such as the YMCA bench press, sub-maximal BBP, and push-ups, have been established but also pose some risk of injury. The theory is that performing a dumbbell floor press may be a safer alternative, as it provides a stable base for the scapula and shortens the range of motion on the press, eliminating excessive anterior humeral slide. Two case studies have shown that exercises using a bench in horizontal and push-ups can cause bilateral shoulder dislocation. This study aims to fill the gap in the literature by examining the relationship between the dumbbell floor press and the barbell bench press. The findings of this study may provide health professionals with an alternative means of assessing upper body pressing strength for participants who may be at risk of injury with traditional testing protocols.
Poster submission was sponsored by Dr.Ken Anderson, (Sports Science Department) for course SPSC 4256 and was presented at the New Westminster campus on April 12, 2023, for Student Research Days 2023.Not peer reviewe
GSL-Bench: High Fidelity Gas Source Localization Benchmarking
No full textGas Source Localization (GSL) is a challenging field of research within the robotics community. Existing methods vary widely and each has its own strengths and weaknesses. Existing GSL evaluations vary in environment size, wind conditions, and gas simulation fidelity, thereby complicating objective comparison between algorithms. They also lack photo-realistic rendering for the integration of obstacle avoidance. In this paper, we propose GSL-Bench, a benchmarking suite to evaluate the performance of GSL algorithms. GSL-Bench features high-fidelity graphics and gas simulation. Realism is further increased by simulating relevant gas and wind sensors. Scene generation is simplified with the introduction of AutoGDM+, capable of procedural environment generation, CFD and particle-based gas dispersion simulation. To illustrate GSL-Bench's capabilities, three algorithms are compared in six warehouse settings of increasing complexity: E. Coli, dung beetle and a random walker. Our results demonstrate GSL-Bench's ability to provide valuable insights into algorithm performance.https://sites.google.com/view/gslbench/ Website providing additional results and instructionsAerospace Engineerin
Supercapacitor Test Bench
Get PDFBakalaureusetöö
Tehnika ja tehnoloogia õppekavalPaljud on küll kuulnud ülikondensaatorist ja selle headest omadustest millest olulisemateks võiks lugeda kiiret laadimist ning väga suurt laadimis- tühjenemistsüklite arvu, kuid ülikoolis tudengina pole olnud võimalust ülikondensaatorit näha või katsetada. Selle bakalaureusetöö eesmärgiks ongi valmistada katsestend kus tudengid saavad laboratoorses töös kokku panna katsestendi vastavalt skeemile, ning seejärel katsestendiga teostada mõõtmisi millest järeldada kuidas käitub ülikondensaator laadimisel ja tühjenemisel.
Töö teoreetilises osas antakse ülevaade energiasalvestitest ja nende põhiparameetritest, ning kirjeldatakse ülikondensaatori ehitust, omadusi ja kasutusvaldkondi. Töö praktiline osa hõlmab endas katsestendi skeemi valmistamist programmiga Circuit wizard ning skeemi põhjal valmistati reaalne ülikondensaatori katsestend. Viimases osas on lõputöö autori poolt koostatud laboratoorne töö, mille vajalikud mõõtmised teostatakse ülikondensaatori katsestendiga. Katsestendiga on võimalik mõõta kuidas pinge muutub ülikondensaatori täitumisel ning on võimalik jälgida pinge muutumist ka ülikondensaatori tühjenemisel.Many have heard of the supercapacitor and its good properties. One of the most important properties are fast charging and very large of charge-discharge cycles, but as student in university it has not been possible to see or test the supercapacitor. The aim of this bachelor’s thesis is to prepare a test bench, where students can assemble a test bench in the laboratory according to the scheme, and then perform measurements with the test bench to see how the supercapacitor behaves during charging and discharging.
The theoretical part of the work gives an overview of energy storages and their basic parameters, and describes the construction, properties and applications of the supercapacitor. The practical part of the work involves the to build test bench scheme with the program Circuit wizard, and on the basis of the scheme to build a supercapacitor test bench. In the last part, the author of the dissertation has prepared a laboratory work, the necessary measurements of which are performed with a supercapacitor test bench. With the test bench it is possible to measure how the supercapacitor voltage changes on charging and monitor how voltage decrease while discharging
- …
