165 research outputs found

    The need for a consensus on the locution "central nuclei" in striated muscle myopathies

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    "Central nuclei" and "centrally located nuclei" are both widely used expressions to describe the nuclear positioning in skeletal muscle fibers during embryogenesis or muscle regeneration, as opposed to the definitive, subsarcolemmal (i.e., peripheral) nuclear position in adult muscle fibers. The two expressions are mutually exclusive in major databases of scientific literature and authors from different research groups seem to opt for one or the other stochastically, though are consistent with their choice over time. This poses a problem, since a search for one or the other set of keywords retrieves different subsets of articles, limiting the bibliography available. Defining nuclear position is very important in pathology, since many muscle disorders share the mispositioning of nuclei in the muscle fibers (Romero and Bitoun, 2011). In healthy conditions myonuclei are spaced in the periphery of the muscle fibers in such a way that the distance between them is maximized, while they are often found in the center of the myofibers in pathological conditions (recently reviewed by Folker and Baylies, 2013). This phenomenon makes nuclear positioning a common morphological marker for myopathies and the expressions used to describe it are widely used in basic research as well as in diagnosis. Therefore, the issue of using the expression "central" rather than "centrally located nuclei" is not limited to basic research in myology and can affect translational medicine and clinical practice as well, going far beyond a simple matter of semantics. We think there is an urgent need to establish an agreement on the term used in myopathy research as well as in clinical guidelines, "central nuclei" being our favorite choice. This article means to bring this issue to the attention of the scientific community of myologists, including health care professionals. Below, we discuss in detail the two options and justify our propos

    La comunità albanese in Italia: caratteristiche e sfide tra immigrazione e integrazione. Il caso della Lombardia e dei lavoratori altamente qualificati

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    In 2021, Albanians were the second-largest nationality of first-generation migrants to Italy. This research provides a snapshot of Albanians in Italy who are working in sectors with the potential for future benefit to Albania. It examines the socio-economic characteristics, expectations, and plans of Albanians in Italy (employed in the agri-business, cultural preservation and heritage, and social enterprise sec-tors, as well as a residual category that includes other sectors). The Italian region with the highest number of Albanian immigrants is Lombardy, the territorial focus of this research, which comprised an in-depth questionnaire administered to 134 respondents. Key outcomes show that skilled Albanians are highly integrated into local society: most respondents have acquired Italian citizenship, 70% are in full-time work, and overall their income is higher than the national average. Their relationship with Italy is not always smooth, with many haunted by memories of difficulties in the early days following their arrival, and continued stigmatization. Despite this, most see their future in Italy while experiencing a complicated relationship with Albania, a place to return for short visits – but perhaps never to settle in again

    Mapping and Profiling of Albanian Diaspora. An economic and social survey in five Italian regions. Overview of the situation in France and Belgium

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    The aim of the book is to better understand the characteristics of the Albanian diaspora in the three countries, investigating plans and expectations of migrating Albanian citizens with particular interest to a possible direct or indirect contribution and investment. Diaspora and diaspora networks are indeed considered key possible actors to economic and financial contribution to the country of origin, besides the help they grant through family remittances. More particularly, they are recognized for their more trusted and lasting relationships with domestic actors, being able to merge self-economic and solidarity motivation to invest in the country of origin and also be able to mobilize larger networks and forms for capitals and resources. Based on these assumptions, the research had been designed to verify and analyse the extent and the conditions in which could the Albania diaspora abroad be a relevant economic player benefiting the development and investment policies in Albania. The goal is not to make a comparison between Albanian Diaspora communities in Italy, France, and Belgium, but rather to provide an analysis on the driving factor, which has stimulated the migration in these countries. Meanwhile considering that the Albanian Diaspora in Italy is amongst the largest Diaspora abroad, the research is mainly focused on the different patterns of communities in the main five regions of Italy. Moreover, it provides a profiling of Albanian citizens residing in Italy, who have declared an interest in investing in Albania, in order to offer an instrument aimed at strengthening the role of the diaspora for the development of Albania

    La comunità albanese a Roma e nel Lazio: uno sguardo oltre gli stereotipi

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    La comunità albanese rappresenta la seconda comunità di stranieri in Italia in termini di numerosità. Le analisi realizzate sulla totalità della comunità albanese (si veda ad esempio il rapporto annuale del Ministero del Lavoro e delle Politiche Sociali 2019) mettono in evidenza una rilevante specializzazione della comunità nel settore edile - in cui è impiegato il 27,4% (a fronte dell’8,1% dei non comunitari) - e l’Industria in senso stretto (ulteriore 19%). Pur essendo prevalentemente concentrata nel Nord Italia e in Toscana, la comunità albanese nel Lazio è comunque significativa. Questo lavoro presenta i risultati di uno studio sui cittadini albanesi nel Lazio svolto a partire dalla seconda metà del 2019 e incentrato prevalentemente su alti profili. L’indagine è stata realizzata dal Centro Studi di Politica Internazionale (CeSPI) nel quadro di un più ampio programma dell’Organizzazione Internazionale per le Migrazioni – OIM Albania. Il programma “Engage the Albanian Diaspora to the Social and Economic Development of Albania” (2018-2020), finanziato dall’Agenzia Italiana per la Cooperazione allo Sviluppo, prevede il supporto al Governo albanese per coinvolgere la diaspora nello sviluppo dell’Albania, con particolare attenzione alle comunità residenti in Italia

    Place-based strategies or territorial cooperation? Regional development in transnational perspective in Italy

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    Italy has been at the forefront in the implementation of place-based regional development strategies during the 2000s, and it constitutes therefore a privileged point of view to investigate the contents of the approach, its potentialities as well as its limitations. In light of those limitations, several scholars have recently directed their attentions toward a typology of policies - territorial cooperation - which may be regarded as a trans-regional and transnational approach to regional development. In the paper, we offer a review of the main criticisms of place-based strategies and of the main distinctive dimensions and the potential value added of territorial cooperation initiatives, in light of recent debates about territorial vis-à-vis relational approaches to regional development. The identification of transnational spatial units, joint management authorities and trans-regional strategies, it is argued, may indeed help to overcome some of the limitations of place-based strategies - namely, the risk of policy capture, territorial introversion and communitarian confinement - while incurring in others - institutional isomorphism, technocratic management and democratic deficit. As the European political and economic space become increasingly trans-scalar and networked, the two policy domains may potentially learn from each other, and a new generation of local policies may emerge which are both territorial and relational, place-based and trans-regional. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.Italy has been at the forefront in the implementation of place-based regional development strategies during the 2000s, and it constitutes therefore a privileged point of view to investigate the contents of the approach, its potentialities as well as its limitations. In light of those limitations, several scholars have recently directed their attentions toward a typology of policies – territorial cooperation – which may be regarded as a trans-regional and transnational approach to regional development. In the paper, we offer a review of the main criticisms of place-based strategies and of the main distinctive dimensions and the potential value added of territorial cooperation initiatives, in light of recent debates about territorial vis-a`-vis relational approaches to regional development. The identification of transnational spatial units, joint management authorities and trans-regional strategies, it is argued, may indeed help to overcome some of the limitations of place-based strategies – namely, the risk of policy capture, territorial introversion and communitarian confinement – while incurring in others – institutional isomorphism, technocratic management and democratic deficit. As the European political and economic space become increasingly trans-scalar and networked, the two policy domains may potentially learn from each other, and a new generation of local policies may emerge which are both territorial and relational, place-based and trans-regional

    Catalogo delle cose d'arte e di antichità d'Italia.

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    V. 2. Pisa, a cura di Roberto Papini; V. 4. Zara, a cura di C. Cecchelli; V. 5. Urbino, a cura di Luigi Serra; V. 6. Fiesole, a cura di Odoardo H. Giglioli; V. 7. Treviso, a cura di Luigi Coletti; V. 8. Vercelli, a cura di Anna Maria Brizio; V. 9. Assisi, a cura di Emma Zocca; V. 10. Cividale, a cura di Antonino Santangelo; V. 11. Brescia, a cura di Antonio Morass
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