57 research outputs found
Mycoses
Tinea corporis is a superficial fungal infection involving glabrous skin that is caused by the invasion and proliferation of dermatophytes in the stratum corneum. Tinea corporis classically manifests as asymptomatic or itchy, single or few, erythematous, circular, or annular scaly plaques that often display central clearing giving rise to an expanding ring-like lesion and a well-demarcated margin that may be papular, pustular, or vesicular. The term trichophytic Majocchi granuloma refers to a deep follicular involvement with perifollicular granulomatous/fibrotic reaction that manifests as a solitary or multiple persistent papulopustules or crusted plaques. Tinea capitis is the most common paediatric dermatophyte infection worldwide, with a particular predilection for black populations. Pityriasis versicolour in skin of colour usually presents as round or oval macules coalescing into larger patches that most commonly involve the upper chest/back. Tinea nigra is clinically typified by a single or multiple brown or black patches on the palms and/or soles
Red dots caught red handed: Dermoscopy of genital psoriasis
Dermoscopy is an in vivo diagnostic technique that aids in the visualization of epidermis, dermoepidermal junction, and papillary dermis. Histopathology contributes tremendously in confirming the clinical diagnosis of unusual presentations of inflammatory skin disorders. Being noninvasive, dermoscopy assists significantly in differentiation of many inflammatory skin disorders which clinically resemble one another. In this report, authors describe the importance of dermoscopy in the diagnosis of genital psoriasis which was mimicking dermatophytic infection and contact dermatitis
Dermoscopic evaluation of idiopathic guttate hypomelanosis: A preliminary observation
Background: Depigmented skin lesions are of great concern in the society, especially in the Indian subcontinent. These comprise many infective and inflammatory conditions that cause apprehension and anxiety among patients due to the social stigma attached to these conditions. Idiopathic guttate hypomelanosis (IGH) appears similar to many depigmented lesions and differentiation of IGH from these conditions is difficult clinically as well as histopathologically. Methods: Clinically suspected IGH were included in the study. All IGH lesions were confirmed by histopathology. Clinical data and dermoscopic patterns were analyzed and presented in proportions and percentages. Results: Thirty patients were included in the study with 16 females and 14 males. Dermoscopy showed amoeboid, feathery, petaloid and nebuloid patterns in 12, 7, 6 and 1 patients respectively. Four patients had combination of these patterns. Conclusion: Dermoscopy of IGH revealed consistent patterns. Hence, we propose these patterns were specific to IGH and help clinician to differentiate many depigmented skin lesions from IGH in clinical practice. However, histopathology must be done for confirmation of diagnosis. Further studies on dermoscopy of IGH with histopathology correlation are proposed
Dermoscopy of non-melanocytic and pink tumors in brown skin: A descriptive study
Introduction: Skin tumors are classified as melanocytic and non-melanocytic based on presence of melanocytes and melanin pigment in the tumor. Dermoscopy, being a non-invasive technique, is a proven method in recognizing the non-melanocytic and pink tumors by showing specific patterns. In Indian subcontinent, reports on dermoscopy of non-melanocytic and pink tumors are confined only to case reports. Authors studied dermoscopic features of non-melanocytic and pink skin tumors in dermoscopy. Materials and Methods: Study was carried in a tertiary hospital attached to S.Nijalingappa Medical College, Bagalkot, between January and December 2016. It was a descriptive study. Patients with signs of non-melanocytic and pink tumors were selected. Demographic data, such as age, gender, and clinical variables in terms of site of tumor and duration were documented. Manual DermLite 3 and videodermoscopy were employed. Both polarized and non-polarized versions were used for examination. Results: Totally 128 patients were present with 75 females and 61 males. Study included pyogenic granuloma (39), squamous cell carcinoma (4), basal cell carcinoma (30), keratoacanthoma (3), seborrheic keratosis (15), trichoepithelioma (2), syringoma (5), apocrine hydrocystoma (2), fibrokeratoma (5), dermatofibroma (6), epidermal cyst (7), sebaceous hyperplasia (2), Bowen's disease (1), steatocystoma multiplex (1), Lymphangioma circumscriptum (3) and milia (3). Numbers in parenthesis indicate number of patients. Conclusion: Dermoscopy of non-melanocytic and pink tumors demonstrates characteristic patterns which vary from white, yellow, brown to blue and red color depending on presence of keratin and hemoglobin. Patterns differ based on the type skin color. Recognition of distinctive vascular and keratin related pattern is of great help in the diagnosis of skin tumors. To the best our knowledge, this is first report of dermoscopy of non-melanocytic and pink tumors on a larger scale from Indian subcontinent
Dermoscopy of partially pigmented Bowen's disease in an immunocompromised patient: An emphasis on white rosettes
Comparative study of safety and efficacy of oral betamethasone pulse therapy and azathioprine in vitiligo
Background: Vitiligo is a common skin disorder causing depigmented macules that can impair a patient's quality of life. There are number of treatment modalities are available but at the present, there are no studies compairing betamethasone pulse therapy versus azathioprine daily therapy in treatment of vitiligo. Objectives: To compare the safety and efficacy of Azathioprine daily and Betamethasone pulse therapy in the treatment of in vitiligo. Materials and Methods: We included two vitiligo patient groups. namely group A and group B Patients of group A were given oral Azathioprine to be given 50mg twice daily and those of second group B, Betamethasone were given as a single oral dose of 5 mg on two consecutive days per week. Therapy in both groups was given for a total of 6months with follow up at 1, 3 and 6th month. Clinical photographs were taken at each visit. Side-effects if any were noted. Results were calculated with help of VASI score (vitiligo area severity index). Results: At the baseline: The patients to group A (SD 3.81± 2.3) and of group B (SD 3.76± 2.28) were having depigmented patches (P = 0.90). At the first follow up: Although there was significant improvement with perifollicular repigmentation started in both groups but the patients are of group B (SD 3.38±2.06) were showing slower response as compared to oral group A (SD 3.70± 2.28). At the second follow up: Remarkable improvement is seen in both groups compared (P = 0.17). At the third follow up: Significant improvement is seen in both groups compared (P = 0.09). Conclusions: Azathioprine and betamethasone pulse therapy are equally effective in treatment of vitiligo
White rosette in discoid lupus erythematosus: a new dermoscopic observation
White rosettes are shiny white structures seen as four oval-shaped points that come together in the center. They resemble four-leaf clover [1]. Earlier it was thought they were specific for actinic keratosis and squamous cell carcinoma, but they are noted in many other conditions [2]. With polarized light dermoscopy, it is evident that rosettes are seen only and they are due to the optical effect between polarized light and follicular structures [3]. Here, authors describe cases of discoid lupus erythematosus (DLE) demonstrating rosettes under polarized dermoscopy
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