760 research outputs found
sj-docx-1-pie-10.1177_09544089221150703 - Supplemental material for Investigations on erosion performance of carbon fiber–epoxy-based composite adhesion on 16Cr5Ni steel
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221150703 for Investigations on erosion performance
of carbon fiber–epoxy-based composite adhesion on 16Cr5Ni steel by Mithlesh Sharma, Deepak Kumar Goyal, Anuj Bansal, Anil Kumar Singla, Neel Kanth Grover, Munish Kumar Gupta and Navneet Khanna in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
Recent development in the strategies projected for chikungunya vaccine in humans
No full textManu Goyal,1 Anil Chauhan,2 Vishavdeep Goyal,3 Nishant Jaiswal,1,2 Shreya Singh,4 Meenu Singh1,2 1Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India; 2Indian Council of Medical Research Advanced Centre for Evidence Based Child Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India; 3Apollo Hospitals International Limited, Ahmedabad, India; 4Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India Abstract: The unprecedented epidemic spread of chikungunya worldwide illustrates the critical need for potent vaccines and therapeutic interventions. The morbidity and mortality associated with this arboviral infection has become a major public health problem in many countries across different continents. Increasing public–private partnerships have opened new avenues in research and development of vaccines. This review mainly focuses on the recent advances in patented approaches for chikungunya vaccine development and the forthcoming challenges. Keywords: chikungunya, epidemics, CHIKV vaccine candidates, clinical trials, human
Dynamics of Network Formation Processes in the Co-Author Model
No full textThis article studies the dynamics in the formation processes of a mutual consent network in game theory setting: the Co-Author Model. In this article, a limited observation is applied and analytical results are derived. Then, 2 parameters are varied: the number of individuals in the network and the initial probability of the links in the network in its initial state. A simulation result shows a finding that is consistent with an analytical result for a state of equilibrium while it also shows different possible equilibria.Dynamics, Network, Game Theory, Model,Simulation, Equilibrium, Complexity
Effect of a diabetes education camp on perception of insulin therapy in patients of type-2 diabetes mellitus
No full textIntroduction: Type-2 Diabetes Mellitus is a pandemic now and most of the patients are treated on OHAs. There are very specific indications to initiate insulin therapy. However, very often, physician's attempt to introduce insulin is met with stiff resistance from the patient. Methods: This was a single-centre, cross-sectional, interviewer-administered survey study, conducted in order to assess the perception of Insulin therapy among patients with type 2 Diabetes Mellitus as well to see the effects of a structured 'Diabetes Education Program' on this perception. Pre-Education & Post-Education data was compiled and analyzed. Result: Out of 88 subjects, 60 were males and 28 females. 14 subjects were on non-pharmaceutical management, 67 were on OHAs only and 7 were taking OHAs+Insulins. Worst Pre-Education perceptions were about: feeling fault of self (in the sense of inability to control diabetes), feeling that insulin therapy means that disease has become much worse. Younger patients and better educated patients had better perceptions about insulin therapy. There was significant Post-Education improvement was found in perception, across all four groups. Conclusion: This Study could identify the worst perception problems for initiation of insulin therapy in patients of type-2 diabetes. A structured 'Diabetes Education Program was highly effective in improving patients' perception about insulin therapy. Patient's education level and availability of 'Diabetes Education Program' were the two most important factors in determining the level of perception of insulin therapy in serving soldiers & their families
Isolated propeller aeroacoustics at positive and negative thrust Author links open overlay panel
No full textUsing propellers in negative thrust conditions can potentially result in many benefits, such as a steeper descent, a reduced landing run, reduced community noise, energy regeneration, etc. However, the aerodynamics and aeroacoustics of propellers in this regime are not well understood. This paper presents an aeroacoustic analysis of an isolated propeller operating in both positive and negative thrust conditions, using scale-resolved lattice-Boltzmann very large eddy simulations and the Ffowcs Williams & Hawkings analogy. The propeller was operated at a constant tip Mach number so that any differences in tonal noise between positive and negative thrust conditions were due to changes in blade loading. Results showed that the flow separation around the blades in the negative thrust case led to a 2 to 6 times higher standard deviation in integrated thrust compared to the positive thrust case. The blade loading in the negative thrust case shows the amplitude of fluctuations up to 18% for inboard sections and up to 30% near the blade tip compared to the time-averaged loads. The noise in the propeller plane is 10 dB higher in the positive thrust regime than in the negative thrust regime at a given absolute thrust level of
. The lower noise at negative thrust is caused by two factors: the lower magnitude of the negative torque compared to the positive torque at a given thrust level and the shift of the blade loading inboard in the negative thrust condition due to the stall of the blade tip. Along the propeller axis, the negative thrust regime has 13-15 dB higher noise because of the increased broadband noise generated by the flow separation. In the negative thrust case, the noise along the propeller axis (89 dB) and propeller plane (92 dB) are comparable. However, this is not the case for the propulsive case. The comparison of noise in the vicinity of the propeller plane showed that using the propellers in negative thrust conditions allows for a steeper and quieter descent compared to a conventional descent; as long as the magnitude of the negative torque produced is equal to or less than the torque required to operate the propeller in a conventional landing
Bounded Rationality and Repeated Network Formation
No full textWe define a finite-horizon repeated network formation game with consent, and study the differences induced by different levels of individual rationality. We prove that perfectly rational players will remain unconnected at the equilibrium, while nonempty equilibrium networks may form when, following Neyman (1985), players are assumed to behave as finite automata. We define two types of equilibria, namely the Repeated Nash Network (RNN), in which the same network forms at each period, and the Repeated Nash Equilibrium (RNE), in which different networks may form. We state a sufficient condition under which a given network may be implemented as a RNN. Then, we provide structural properties of RNE. For instance, players may form totally different networks at each period, or the networks within a given RNE may exhibit a total order relationship. Finally we investigate the question of efficiency for both Bentham and Pareto criteria.Repeated Network Formation Game, Two-sided Link Formation Costs, Bounded Rationality, Automata
Inferring object states and articulation modes from egocentric videos
No full textWe develop algorithms for understanding objects from the point of view of interacting with them. There are two key aspects to obtaining such an understanding. First, objects can occur in different states and we need features that are sensitive to such states. Second, different objects can be articulated in different ways and we need to understand how to correctly infer their modes of articulation. We propose self and weakly supervised techniques to obtain such an understanding of objects purely through observation of how humans interact with the world around them through their hands. Our experiments on the challenging EPIC- KITCHENS dataset show the merits of using human hands as a probe for understanding objects.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-05-01The student, Rishabh Goyal, accepted the attached license on 2021-04-27 at 12:26.The student, Rishabh Goyal, submitted this Thesis for approval on 2021-04-27 at 13:39.This Thesis was approved for publication on 2021-04-28 at 09:43.DSpace SAF Submission Ingestion Package generated from Vireo submission #16585 on 2021-09-16 at 17:06:08Made available in DSpace on 2021-09-17T02:34:49Z (GMT). No. of bitstreams: 2
GOYAL-THESIS-2021.pdf: 26378428 bytes, checksum: 5fb34e7c3f1a83a84f3c5ba07fefd80f (MD5)
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Previous issue date: 2021-04-28Embargo set by: Seth Robbins for item 118591
Lift date: 2023-09-17T02:34:57Z
Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD systemU of I Onl
Aerodynamics and Far-field Noise Emissions of a Propeller in Positive and Negative Thrust Regimes at Non-zero Angles of Attack
No full textThis paper studies the effect of operation at non-zero angles of attack on the aerodynamic performance and far-field noise emissions of an isolated propeller operating at positive and negative thrust conditions. To achieve this, scale-resolved lattice-Boltzmann very large eddy simulations coupled with the Ffowcs Williams & Hawkings analogy have been used. The results show that when the propeller operates with a 10◦ angle of attack at the positive thrust condition, the blade loading increases on the advancing side and decreases on the retreating side, leading to a 9.6% increase in integrated thrust (when computed along the propeller axis) and a negligible increase (0.1%) in propeller efficiency. Conversely, at the negative thrust condition, the operation at 10 deg angle of attack results in a 7.9% decrease in thrust magnitude and an 11.1% reduction in energy-harvesting efficiency. In this condition, the positively cambered blade sections exhibit dynamic stall at the 10◦ angle of attack, resulting in broadband fluctuations of up to 10% of the mean loading. As a result of the opposite change in absolute blade loading in the negative thrust condition compared to the positive thrust condition at the 10◦ angle of attack, the change in the noise directivity is also the opposite. Whereas in the positive thrust case, the noise increases in the region from which the propeller is tilted away (i.e., below the propeller at a positive angle of attack), in the negative thrust case, it is the other way around. This study highlights the need to account for non-zero angles of attack in propeller design and optimization analyses
Application of uncertainty quantification techniques for a nonlinear 1:2 internal resonance system
No full textNonlinear phenomena based resonating devices offer a very promising role as efficient and accurate MEMS devices in a rapidly growing and improving area of MEMS based sensing and actuation. The requirement of high reliability and accuracy stipulates very strict performance metrics of these devices. In order to understand the effects of any input variability on the output, a robust modeling and simulation technique should be developed which predicts the device behavior sufficiently accurately, while at the same time considering the computational complexity associated with complete nonlinear analytical modeling. This works deals with a nonlinear T-shaped 1:2 internal resonance autoparametric resonator and looks into the uncertainty quantification aspect of it. The aleatoric uncertainties of material and geometric properties are considered and their quantification problem is addressed. The solution of the system, which is a two stepped process considering linear modeshapes and frequencies and nonlinear averaged Lagrangian, is modified for piezoelectric actuation. Simulation for uncertainties is done for the linear and nonlinear parts separately and effects of parameter variation on the final output are brought out. Several techniques of efficient simulation are presented and sensitivity of the device towards tuning is established. An attempt of experimental uncertainty quantification is presented with a macro-scale model built to replicate the functionality of the MEMS device. Various issues related to its operation in the macro domain are brought out and suggestions for further improvements are made based on the current observations. Future research on developing the MEMS device for characterization and uncertainty studies is suggested
A case of accidental vincristine overdose and effective use of therapeutic plasma exchange in its management
No full textVincristine is a common drug used in hematological malignancy with a maximum per dose limited to 2 mg mainly to limit neurotoxicity. Vincristine overdose and wrong route of administration, though has been reported in world literature, but its appropriate management is still undefined. We report a case of Hodgkin lymphoma being treated with adriamycin, bleomycin, vinblastine and dacarbazine protocol, where vincristine was accidently administrated instead of vinblastine due to its “look-alike, sound-alike” nature. The patient developed severe toxicity due to the same, which was effectively managed by therapeutic plasma exchange
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