102,840 research outputs found
Distribuzione ed analisi molecolare degli anticorpi anti-F(ab’)2 nell’infezione da HIV-1.
Drug injection in jugular veins: a new risk factor for vascular diseases in HIV-infected patients?
Effetto della terapia con zidovudina sulla presenza di sequenze provirali di HIV-1 nella saliva di soggetti sieropositivi
Difficulties in classifying a/g recombinants: methodological problems or genetic variability?
Thirty pol gene plasma-derived sequences clustering with the circulating recombinant form (CRF) 02_AG
(IbNG) (bootstrap 100%) were evaluated to analyze the genomic composition. Subtype assignment was also
phylogenetically confirmed by C2–V3 region analysis for 18/21 sequences evaluated. Thereafter, we compared
the genomic recombination of the CRF02_AG/IbNG prototype as predicted by bootscanning and Jumping
HMMER software (jpHMM) to that of our strains. With these methods, 27% and 50%, respectively, of our
clinical sequences demonstrated the same pol structure as the prototype CRF02_A/G-IbNG. However, in subtrees
built for each segment predicted by jpHMM (with a bootstrap value of more than 75%), all fragments
clustered with IbNG and were distinct from A and G clades. Overall, our sequences resulted in true members
of CRF02_AG–IbNG, which, however, appeared to be a subtype phylogenetically separate from A or G,
at least with regard to the pol gene
Access to Health Services for Undocumented Immigrants in Apulia
This paper, part of a larger epidemiological study carried out between 2004 and 2010, analyzed immigrants frequenting the largest Apulian regional hospital (Bari Policlinico). Our aim was to evaluate the perception on the part of undocumented immigrants of their rights of access to the National Health Care services and whether this privilege is actually utilized. An anonymous multi-language questionnaire was distributed to all patients with STP (code number for temporary presence of foreigners) at the immigrant outpatient Infectious Diseases Clinic of Bari from June 2009 to June 2010. Questions were related to nationality, date of arrival in Italy, use of health facilities in the 2 years prior to the compilation of the questionnaire, and their understanding of STP. The patients were also screened for infectious diseases (HIV-Ab, HBsAg, HCV-Ab, VDRL, TPHA and Mantoux). A total of 256/272 patients completed the questionnaire; the meaning of STP was unknown to 156/256 (60.9 %) patients, only 54/256 (21 %) knew the exact meaning of STP and only 42/54 (76.6 %) of the latter knew how long STP was valid. Moreover, 128/256 (50.7 %) were aware that doctors from the emergency unit were not allowed to notify police regarding presence of illegal immigrants. Regarding clinical data 3 % were HIV+ (8/256), 5 % (13 patients) positive for TPHA, 5 % for HBsAg, 2 % were HCV (five patients). A >10 mm diameter infiltrate of Mantoux test was noted for 44 % of patients. A lower prevalence than expected for infections such as HIV, HBV or HCV was noted for immigrants compared to data from their countries of origin. At present, large-scale political solutions to the challenges of facilitating access to health facilities for undocumented immigrants are lacking in Italy. The development of communication systems is fundamental to improving access to health services and to creating links between immigrants and the healthcare system
New principle for the simultaneous detection of total and immunoglobulin M antibodies applied to the measurement of antibody tohepatitis B core antigen
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