204 research outputs found

    Knowledge sharing and organizational performance

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    Malaysia is one of the industrializing and emerging countries that willing to undertake the rapid economic change and investing in more productive capacity. The contribution of output and employment from the manufacturing sector has been steadily increasing, while the economy from industrial era has shifted to information era; focusing more on knowledge-based economy. Manufacturing companies in Malaysia are facing challenges and opportunities from a rapidly changing operating environment and industrial revolution, generation of new sustainable value chain systems, and contribution to the knowledge-based economy. The aim of this study is to examine the influence of tacit and knowledge sharing on organizational performance among manufacturing companies in Malaysia. This quantitative study would provide an insight on the importance and effects of tacit and explicit knowledge sharing toward organizational performance among Malaysia’s manufacturing companies. The key underpinning theory of this study is Knowledge-based View (KBV). Data were obtained from 145 manufacturing companies in Malaysia via the representative of Production Managers. This study provides fundamental knowledge and direction for researchers in further research as well as practitioners to constantly improve their organizational performance through the stimulation of tacit and explicit knowledge sharing practices

    Quality of life measures in Barrett's Oesophagus care pathways

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    IMPLEMENTATION OF ENERGY EFFICIENT AIR-CONDITIONING EQUIPMENT

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    Bachelor'sBACHELOR OF SCIENCE (BUILDING

    Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

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    Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic.</p

    Recognition of energy-based activities performed by the aged

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    Over the years, there has been a boom in the mobile technology industry, namely the smartphone industry. With smartphone consumption on the rise, the producers in the mobile industry are compelled to innovate and produce better smartphones with more features than the previous model of smartphone. This project aims to utilize the embedded microphones in our smartphones to recognize home related activities through the unique sound signatures that these activities produced. Through some research, it is shown that while speech and music recognition have been around for some time, the area of environmental sound recognition is relatively unexplored. However, the basic idea and model composition of environmental sound recognition is similar. Through this project, Mel Frequency Cepstral Coefficients (MFCCs) will be used for feature extraction along with the Convolutional Neural Network (CNN) classification model composition. The outcome of this project was satisfactory, however there is still room for improvement in terms of the accuracy. This report includes the research and model process of the project as well as suggestions for potential future works.Bachelor of Engineering (Electrical and Electronic Engineering

    Targeting the cell cycle in esophageal adenocarcinoma: An adjunct to anticancer treatment

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    Esophageal adenocarcinoma is a major cause of cancer death in men in the developed world. Continuing poor outcomes with conventional therapies that predominantly target apoptosis pathways have lead to increasing interest in treatments that target the cell cycle. A large international effort has led to the development of a large number of inhibitors, which target cell cycle kinases, including cyclin-dependent kinases, Aurora kinases and polo-like kinase. Initial phase I/II trials in solid tumors have often demonstrated only modest clinical benefits of monotherapy. This may relate in part to a failure to identify the patient populations that will gain the most clinical benefit. Newer compounds lacking the side effect profile of first-generation compounds may show utility as adjunctive treatments targeted to an individual's predicted response to treatment
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