1,123 research outputs found
Letter: R.F. Pettigrew to H.L. Loucks, May 30, 1916
No full textR.F. Pettigrew articulates to H.L. Loucks his distaste for the book that Loucks recommended to him. Pettigrew also mentions that he would prefer to remain distanced from any conference with the author of the book. Pettigrew expresses great admiration and interest in Loucks' manuscript and desire to read it further
Informatieverwerking tijdens de bestekfase
No full textOTB Research Institute for the Built Environmen
Newspaper Clipping: Author Cornwell wants to help solve Civil War mystery
No full textA newspaper clipping of an article titled 'Author Cornwell wants to help solve Civil War mystery', published in an unknown newspaper on February 15, 2006. The article discusses author Patricia Cornwell's interest in donating funds toward studying what happened to the H.L. Hunley, a Confederate submarine that went missing during the Civil War and was rediscovered and excavated in 2000
Modeling superimposed preeclampsia using Ang II (Angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats
No full textHypertensive disorders of pregnancy are the second leading cause of maternal deaths worldwide. Superimposed preeclampsia is an increasingly common problem and often associated with impaired placental perfusion. Understanding the underlying mechanisms and developing treatment options are crucial. The pregnant stroke-prone spontaneously hypertensive rat has impaired uteroplacental blood flow and abnormal uterine artery remodeling. We used Ang II (angiotensin II) infusion in pregnant stroke-prone spontaneously hypertensive rats to mimic the increased cardiovascular stress associated with superimposed preeclampsia and examine the impact on the maternal cardiovascular system and fetal development. Continuous infusion of Ang II at 500 or 1000 ng/kg per minute was administered from gestational day 10.5 until term. Radiotelemetry and echocardiography were used to monitor hemodynamic and cardiovascular changes, and urine was collected prepregnancy and throughout gestation. Uterine artery myography assessed uteroplacental vascular function and structure. Fetal measurements were made at gestational day 18.5, and placentas were collected for histological and gene expression analyses. The 1000 ng/kg per minute Ang II treatment significantly increased blood pressure (P<0.01), reduced cardiac output (P<0.05), and reduced diameter and increased stiffness of the uterine arteries (P<0.01) during pregnancy. The albumin:creatinine ratio was increased in both Ang II treatment groups (P<0.05; P<0.0001). The 1000 ng/kg per minute–treated fetuses were significantly smaller than vehicle treatment (P<0.001). Placental expression of Ang II receptors was increased in the junctional zone in 1000 ng/kg per minute Ang II–treated groups (P<0.05), with this zone showing depletion of glycogen content and structural abnormalities. Ang II infusion in pregnant stroke-prone spontaneously hypertensive rats mirrors hemodynamic, cardiac, and urinary profiles observed in preeclamptic women, with evidence of impaired fetal growth
A study of the 1984 report An Automatic Proof Procedure For Several Geometries by Th. Bruyn and H.L. Claasen
No full textThis report is a discussion of the 1984 report 'An automatic proof procedure for several geometries' by Th. Bruyn and H.L. Claasen, inspired by a personal desire to understand the work of Th. Bruyn. See: http://resolver.tudelft.nl/uuid:b768c6ce-f625-4236-9b0b-32a47fab143e Bruyn and Claasen prove that certain true propositions of the theory of intersections within the two-dimensional projective geometry over the real numbers can be formulated by use of figures. It is proven that figures obtained by manipulating these figures will also correspond to propositions. The method to do so proves that the obtained propositions are a direct consequence of the original propositions and are therefore proven to be true. One of their main results is to use the theorem of Pappus to generate the theorem of Desargues, thereby proving that Desargues follows from Pappus (something that is well known in projective geometry). This report aims to give a comprehensive explanation of their method as well as a detailed demonstration of their procedure. It is a summary of their work with added explanations and examples
The Narrative Dispossession of People Living with Dementia: Thinking About the Theory and Method of Narrative
No full textIn the beginning …
Once upon a time …
This is the story of …
That’s a good story ….
And they all lived ….
Let me tell you a story ….
Narrative, it seems, is all around us. Bruner (2002) states that we are
‘constantly in the process of making narratives’ (p.3) and that narrative is so
much part and parcel of life that ‘human society cannot run without it’. In
everyday life we recount stories about ourselves and others and in so doing
both represent and construct ourselves. We are the heroes and heroines of our
own stories and occasionally of the stories of others. Our experience, lives and
Selves are storied. In academia narrative has also found a place not only in the
humanities but also the social sciences and even the natural sciences. It would
seem there is no escape from participation in the narrative enterprise - it is a
way of experiencing, relating, thinking and, ultimately, being in the world.
Narrative, as Barthes (1977) said, ‘is simply there, like life itself’ (p.79).
To be sure, the development of narrative as a theory and method has
brought (or constructed) insights into all manner of things. Narrative, emerging
as it did from an interest in the experience of powerlessness (MacKinnon,
1996), was seen as a means of giving voice to those previously at the margins
and has effectively, and prolifically, expanded our understanding of what it is
like to be marginalised, oppressed, victimised, ignored and silenced. But even
as this is so, it is my contention, contra Barthes, that narrative and the process
of narration (narrativity) as we currently conceive and operationalise it
excludes certain individuals and groups of people, creating people without
narrative. These people are those I shall call the ‘narratively dispossessed’. In
the first part of this paper I will seek to outline what I mean by this and work
towards a tentative definition. In the latter part I will attempt to suggest some
ways in which we might try to think about narrative/narrativity somewhat
differently so as to narratively ‘re-possess’ these individuals and groups
Stabiliteit van steenzettingen: Beschouwing van een dijkbekleding als een verend ondersteunde buigligger
No full textBij het bepalen van de sterkte van een dijkbekleding wordt tot nu toe uitgegaan van een losliggend blok als ondergrens voor de stabiliteit. In dit rapport wordt een steenzetting als een ligger beschouwd, waarbij er een normaalkracht opgebouwd wordt, die voor een aanvullende sterkte van de bekleding zorgt. De mate waarin dit gebeurt, is weergegeven in dit rapport. Voor het bepalen van de belasting op de ligger is de maatgevende situatie gebruikt, waarbij net voor het breken van een golf over de steen vlak voor het golffront het maximale drukverschil optreedt. Aan de hand van een vereenvoudigde aanname van het verloop van de belasting over de steenzetting geeft een evenwichtsbeschouwing over het maatgevende blok een reeds bekende formule. In deze formule komt de stabiliteitsparameter <p voor, die beschouwd kan worden als de mate waarin liggerwerking optreedt. Liggerwerking ontstaat wanneer er interactie is tussen de blokken in de toplaag. In dit rapport wordt de interactie veroorzaakt door het eigen gewicht van de blokken, dat voor een initiele inklemming zorgt. Hierbij hangt het gedrag van de steenzetting niet alleen af van een losliggend blok, maar van het gedrag van meerdere blokken. Voor een losliggend blok, zonder liggerwerking, is de waarde van <p ongeveer 3. Het berekenen van de verplaatsingen, momenten en dwarskrachten in de ligger kan met behulp van het numerieke Pascal-programma Winkler gebeuren. Hierbij vindt er een iteratief proces plaats omdat bij elk punt in de ligger, dat opgelicht wordt, geen verende ondersteuning aangenomen kan worden. Als door middel van dit programma bekend is waar de ligger opgelicht wordt, kan met het analytische programma Maple gecontroleerd worden of de waarden van de verplaatsingen, momenten en dwarskrachten overeenkomen. Het programma Maple alleen is dus niet voldoende, aangezien hierin geen iteratie gedaan kan worden. Voor het berekenen in Maple dient de ligger in verschillende secties verdeeld te worden en dienen alle rand- en overgangsvoorwaarden bepaald te worden. De algemene differentiaalvergelijkingen voor elk deel zijn bekend uit "Elasto-statica van slanke structuren" [4]. De sterkte van de ligger wordt nu bepaald door de Iiggerwerking van de steenzetting. In dit rapport wordt aangenomen dat de ligger instabiel wordt als de verplaatsing, het moment of de dwarskracht niet meer aan de sterkte eisen voldoet. Verder kan de ligger bezwijken als de betonsterkte overschreden wordt. Bij het toepassen van deze ontwerpmethode blijkt dat het opneembare moment de maatgevende sterkte eis voor de bekleding vormt. Dit houdt in dat de blokken in de bekleding eerst zullen gaan kantelen alvorens uit te treden. Het kantelen zal echter een extra inklemming opleveren, en dus een stabielere bekleding. De theorie van ir. H.L. Bakker, die de geometrische niet-lineairiteit bij het kantelen beschrijft, blijkt hier op te treden. Het begin van kantelen van een blok hoeft dus geen falen van de bekleding te betekenen, maar het geeft juist een veilige ondergrens voor de stabiliteit van de steenbekleding. In een vervolgonderzoek zou de geometrische niet-lineariteit in het model ingevoegd kunnen worden.Hydraulic EngineeringCivil Engineering and Geoscience
The Barnyard News
No full textThis oversized book (14 x 11) uses the format of a four-page monthly newspaper to present Mother Goose stories and Aesopic fables in paraphrase as news stories. (November alone seems to merit only two pages.) Thus in February we find on the front page Mouse Family Holds Conference by Uncle Aesop Slocum. The article is accompanied by a picture What To Do About Cats? and mentions that eleven different ideas were suggested at the conference. Nearby is an advertisement for Peter Puppy Cat-Belling Service. A month later we learn that Caw Caw Crow was greatly disappointed. He came home from college, where he had learned to think for himself. One of his conclusions was that, if he would stay in the pond as Guinevere Goose has, he could develop white feathers. Caw Caw's father later teaches him a new trick when he returns for spring vacation. The younger crow could find only a half-filled milk bottle to quench his thirst. Horny Bull almost crushes Freddy Frog, and apparently Mrs. Frog stops before she bursts. The fable articles seem to be marked by having Uncle Aesop Slocum as their author. There is about one fable per monthly newspaper. My, the things that have been done with Aesop's fables!This is a hardbound book (hard cover)By H.L. Winborn
A practical treatise on rectal diseases, their diagnosis and treatment by ambulant methods,
No full textMode of access: Internet.NLM copy 2, bookplate of the Greensboro College Library; presented to the College by Mrs. H.L. Prosser
Enhanced pressor-response to angiotensin-I in normotensive men with the deletion genotype (Dd) for angiotensin-converting enzyme
No full textThe insertion (I)/deletion (D) polymorphism of the human angiotensin-converting enzyme gene has emerged as a genetic risk factor for ischemic heart disease. However, the functional consequences of this polymorphism in humans are not known. Ten normotensive men with the DD genotype and 10 with the II genotype participated in a study in which pressor responses to stepwise infusions of incremental doses of angiotensin I (Ang I) and Ang II and Ang II production during Ang I infusion were measured. Pressor responses were expressed as PD20, which reflects the angiotensin dose required to raise mean blood pressure by 20 mm Hg. The PD20 for Ang I in subjects with the DD genotype was significantly lower than that in II genotype subjects (8.8 versus 14.8 ng/kg per minute, P=.0091), whereas the PD20 for Ang II between the two groups did not differ significantly. The ratio of PD20 for Ang I and Ang II in DD subjects was significantly lower than that in II subjects (0.85 versus 0.96, P=.0452), and the venous levels of Ang II during Ang I infusion in DD subjects were significantly higher than those in II subjects (P<.01). Our study has shown increased pressor responsiveness to Ang I, probably as a consequence of the generation of increased Ang II levels, in subjects homozygous for the DD allele of the angiotensin-converting enzyme gene. This result may be relevant to the reported adverse cardiovascular risk conferred by the D allele, as it provides a mechanistic rationale for the association between this polymorphism and cardiovascular disease
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