597 research outputs found
Verity
No full textLowen, a struggling writer grieving her mother\u27s recent death and wondering where her career is headed, is offered an incredible opportunity: to finish bestselling author Verity Crawford’s series of novels. While staying at the Crawford house to finish the series, Lowen uncovers an unpublished autobiography of Verity that reveals shocking secrets about her life. Lowen gets entangled in a heated relationship with Jeremy, Verity’s husband, and is caught in a dilemma of whether she should tell Jeremy about Verity’s secrets.
Author Colleen Hoover is incredibly popular in the romance community today for very good reason. Verity is in production to be her second movie adaptation due to its immense popularity. This book takes romance and layers darker and more suspenseful themes, making it extremely engaging.https://ecommons.udayton.edu/ul_popularromance/1097/thumbnail.jp
Evaluation of the Social Services and Well-being (Wales) Act 2014: Literature Review
No full textEvaluation of the Social Services and Well-being (Wales) Act 2014: Literature Review
Edited by:
Llewellyn, M., Verity, F. and Wallace, S.
Chapter authors:
Chapter 1: Evaluation Overview and Literature Methodology
Verity, F., Wallace, S., Llewellyn, M., Anderson, P. and Lyttleton-Smith, J.
Chapter 2: Well-being literature review
Anderson, P., Lyttleton-Smith, J., Kosnes, L., Read, S., Blackmore, H. and Williams, Z.
Chapter 3: Prevention and early intervention literature review
Verity, F., Read, S. and Richards, J.
Chapter 4: Co-production literature review
Andrews, N., Calder, G., Blanluet, N., Tetlow, S. and Wallace, S.
Chapter 5: Multi-agency literature review
Wallace, C., Orrell, A., Garthwaite, T., Tetlow, S. and Wallace, S.
Chapter 6: Voice and control literature review
Llewellyn, M., Saltus, R., Blackmore, H., Tetlow, S., Williams, Z. and Wallace, S.
Chapter 7: Financial and economic literature review
Phillips, C., Prowle, M., Tetlow S. and Williams Z.Mae’r ddogfen yma hefyd ar gael yn Gymraeg. This document is also available in Welsh. OGL © Crown Copyright Digital ISBN 978-1-80038-948-9.This document is a summary of the extensive review of the literature to inform the evaluation of the Social Services and Well-being (Wales) Act 2014 (hereafter referred to as ‘the Act’).Welsh Governmen
Learning to focus and focusing to learn : more than a cortical trick
No full textThe consequence of many psychiatric and neurodegenerative disorders, such as Parkinson’s disease and schizophrenia, is an impairment in ‘executive functioning’; an umbrella term for several cognitive processes, including the focussing and shifting of attention and the inhibition of responding. The ability to form an ‘attentional set’ involves learning to discriminate qualities of a multidimensional cue, and to subsequently learn which quality is relevant, and therefore predictive of reward. According to recent research, the subthalamic nucleus (STN) and possibly the adjacent zona incerta (ZI) may mediate the formation of attentional set. Dysregulation of the STN as a result of Parkinson’s disease contributes to characteristic motor symptoms, and whilst deep-brain stimulation of this region may treat gross motor impairments, it may also impair cognition. The work in this thesis aimed to expand our understanding of the mechanisms of attentional set-formation, and the role of the STN in this process.
This thesis evaluates new methods for examining set-formation in the attentional set-shifting task; rather than inferring this behaviour solely from the cost of shifting set, modifications to the task design in Chapters 3 & 4 explored several hypotheses designed to exploit a deficit in this behaviour. Chapter 6 revealed that inhibition of this region with designer receptors leads to a disruption in attentional selectivity, which compromises the ability to form an attentional set. This manifested as an inability to parse relevant information from irrelevant, and instead, animals learned the stimuli holistically. The findings in this thesis also suggested that reversal and attentional shifting processes do not operate independently, but rather in a hierarchy, and that consequently, the STN is a region that may be crucial in selecting appropriate responses during associative learning that leads to the formation of an attentional set
Attention regulation and behavioural flexibility in rats with relevance to schizophrenia
No full textSchizophrenia is a neuropsychological disorder in which the neural systems which regulate attention allocation, primarily the dorsolateral prefrontal cortex, are dysfunctional, resulting in deficient gating of attention to irrelevant inputs from the environment. This sensory processing dysfunction hinders goal-directed behaviour to the extent that the subsequent cognitive deficits of schizophrenia prevent many chronic patients from leading normal lives. It is the onus of neuroscience to understand the nature of deficits induced by the disorder, thus providing target mechanisms for remediation of those deficits in patients. To accomplish this, manipulations in rats with relevance to schizophrenia are examined in assays with translation to human neurobiology and behaviour. In this thesis, three manipulations with relevance to schizophrenia, were examined for attentional regulation in the attentional set-shifting task, and similar assays, to determine how different forms of schizophrenia-related pathology influence attentional regulation and behavioural flexibility.
The foremost findings of the experiments herein were that manipulations inducing schizophrenia-related neurobiology, resulted in impaired performance in extradimensional set-shifting and reversal learning. These deficits were found following: acute inhibition of the mPFC in adult rats, in adult rats who had been exposed to a glutamate receptor antagonist during the neonatal period of development, and/or in adult rats who had gestational disruption of neuron proliferation. Across all three manipulations, a clear behavioural pattern of deficient sensory gating, evidenced by responding to irrelevant stimuli during the set-shifting task was found.
These findings suggest that at the core of the cognitive deficits in schizophrenia is the ‘loosening of associations’ such that patients suffer the inability to regulate attention, and limit sensory processing to relevant information. The subsequent aberrant learning about irrelevant information then impairs performance during goal-directed behaviours
Evaluation of the Social Services and Well-being (Wales) Act 2014: Literature Review
No full textThe author list for the literature review is provided below:
Evaluation of the Social Services and Well-being (Wales) Act 2014: Literature Review
Chapter authors:
Introduction and methods
Verity, F., Wallace, S., Llewellyn, M., Anderson, P. and Lyttleton-Smith, J.
Well-being
Anderson, P., Lyttleton-Smith, J., Kosnes, L., Read, S., Blackmore, H. and Williams, Z.
Prevention and early intervention
Verity, F., Read, S. and Richards, J.
Co-production
Andrews, N., Calder, G., Blanluet, N., Tetlow, S. and Wallace, S.
Multi-agency
Wallace, C., Orrell, A., Garthwaite, T., Tetlow, S. and Wallace, S.
Voice and control
Llewellyn, M., Saltus, R., Blackmore, H., Tetlow, S., Williams, Z. and Wallace, S.
Financial and economic
Phillips, C., Prowle, M., Tetlow, S. and Williams, Z.
Service user and carer experiences under the Act
Wallace, S.This report is a summary of the extensive review of the literature to inform the evaluation of the Social Services and Well-being (Wales) Act 2014. This document is a summary of the extensive review of the literature undertaken to inform the evaluation of the Social Services and Well-being (Wales) Act 2014 (hereafter referred to as ‘the Act’).1 The Welsh Government has commissioned a partnership between academics across four universities in Wales and expert advisers to deliver the evaluation. The Act sets out a government vision to produce ‘transformative changes’ in social service public policy, regulations, and delivery arrangements across Wales. It has 11 parts and is informed by five principles that set out a vision to produce transformative changes in public policy, regulations, and service delivery. Aligned to it are structures, processes, and codes of practice. The Evaluation of the Act – a study called IMPACT – is organised around each of the five principles together with a focus on the financial and economic aspects of the Act’s implementation. The approach to undertaking this evaluation research is to structure the evaluation by using the fundamental principles of the Act as the scaffolding. These principles are: • Well-being • Prevention • Co-Production • Multi-agency working • Voice and control There is also a focus on the financial and economic considerations of the implementation of the Act and this area constitutes the sixth evaluation study theme
Pieris daplidice subsp. nitida Verity 1908
No full textPieris daplidice race nitida Verity, 1908 (Rhop. Pal., p. 132; also cited as a “forme” both on this same page and on Pl. XXX, Fig. 9) LT: Asia Minor: Fanaraki, and [Spain]: Andalusia: Malaga (TD: MZUF, Syntypes 2 ♂♂, 2 ♀♀: Kudrna 1983). This taxon was listed as a synonym of either Pontia edusa (e.g. Hesselbarth et al. 1995, 1: 426) or of P. daplidice (García-Barros et al. 2013, p. 960), respectively for the fauna of Turkey and for that of Spain. Kudrna (1983: 58), Wagener (1988: 35) and Hesselbarth et al. (1995: 426) regarded “nitida” Verity, 1908 as an unavailable infrasubspecific name. However, Art. 45.6.4 states that [the rank denoted by a species-group name following a binomen] “is subspecific if first published before 1961 and its author expressly used one of the terms “variety” or “form” …, unless its author also expressly gave it infrasubspecific rank, or the content of the work unambiguously reveals that the name was proposed for an infrasubspecific entity …”. Verity wrote: “[dans les régions] qui semblent être surtout les plus arides (telles que l’Espagne, l’Algérie et l’Asie Mineure) [Pieris daplidice] semble avoir une tendance à être plus petit, à avoir les ailes plus larges, le limbe externe plus convexe, les dessins d’un noir plus profond et à contours plus arrêtés …”. The name Pieris daplidice race nitida Verity, 1908 is therefore available. The originally designated syntypes probably belong to two separate species, but no lectotype was validly designated by any of the preceding authors under Art. 74. Both Pontia daplidice and P. edusa may possibly co-occur in parts of Turkey (see Geiger et al. 1988, Hesselbarth et al. 1995 and John et al. 2013), while only P. daplidice is known to occur in Spain. We therefore designate the ♂ Syntype in MZUF from: [Spanien]: Andalusien: Malaga, C. Ribbe [legit], as Lec- totype of Pieris daplidice race nitida Verity, 1908 (see Fig. 1A). Consequently, the latter name becomes fixed as a junior subjective synonym of Papilio daplidice Linnaeus, 1758.Published as part of Balletto, Emilio, Barbero, Francesca, Bonelli, Simona, Casacci, Luca P. & Dapporto, Leonardo, 2020, Stabilisation of some names of European butterflies (Lepidoptera: Pieridae) in their prevailing usage, pp. 387-395 in Zootaxa 4780 (2) on page 388, DOI: 10.11646/zootaxa.4780.2.11, http://zenodo.org/record/384245
In conversation with M.G.Leanord
No full textVerity Jones and Amanda Webber caught up with M. G. Leonard, author of Beetle Boy, to talk about why getting the science right in children’s fiction is so important and how this book might inspire an interest in understanding and protecting insects
Behavioural examination of the role of the thalamic reticular nucleus in attention
No full textThe ability to selectively attend to aspects of the environment which signal opportunity or danger, while marginalising irrelevant stimuli is critical to an animal’s survival. With finite cognitive resources, the brain must dedicate resources to only those stimuli that are biologically significant. Incoming thalamic information must therefore be filtered. The thalamic reticular nucleus has long been considered critically involved in modulating thalamic sensory processing. Sharing connections with both the thalamus and cortex, it is ideally located to modulate the transfer of pertinent incoming sensory information.
This thesis sought to determine the functional role of the thalamic reticular nucleus in attentional processes by combining lesion techniques and well established behavioural paradigms.
Chapter 3 examined the role of visual thalamic reticular nucleus lesions on performance in a two-alternative forced choice reaction time task when auditory distractors were presented. No effect of the lesion was found. Chapter 4 examined excitotoxic lesions of thalamic retlcular nucleus on performance in the 7-stage attentional set shifting task. No effect of lesion on performance was found. Chapter 5 examined mediodorsal thalamus and rostral thalamic reticular nucleus lesions on performance in the attentional set shifting task. Despite strong connectivity with prefrontal regions known to be involved in this task, there was no effect of either lesion. Finally, chapter 6 examined the effects of reducing dopamine input into the thalamic reticular nucleus on a two alternative forced choice reaction time task. Following bilateral lesions the animals were impaired in the re-orientation of attention – suggesting a critical role for both the thalamic reticular nucleus and dopamine in attentional processes. Taken together, these results suggest that while the thalamic reticular nucleus is involved in attention, it is not involved in every aspect
Selective attention and flexible learning in rats
No full textAbstract redacted"This work was supported by the Biotechnology and Biological Sciences Research Council EASTBIO Doctoral Training Programme in collaboration with Boehringer Ingelheim [grant number: BB/M010996/1]."--Funding acknowledgemen
- …
