62 research outputs found
A novel approach to pharmaco-EEG for investigating analgesics:assessment of spectral indices in single-sweep evoked brain potentials
No full textAIMS To compare results from analysis of averaged and single-sweep evoked brain potentials (EPs) by visual inspection and spectral analysis in order to identify an objective measure for the analgesic effect of buprenorphine and fentanyl. METHODS Twenty-two healthy males were included in a randomized study to assess the changes in EPs after 110 sweeps of painful electrical stimulation to the median nerve following treatment with buprenorphine, fentanyl or placebo patches. Bone pressure, cutaneous heat and electrical pain ratings were assessed. EPs and pain assessments were obtained before drug administration, 24, 48, 72 and 144 h after beginning of treatment. Features from EPs were extracted by three different approaches: (i) visual inspection of amplitude and latency of the main peaks in the average EPs, (ii) spectral distribution of the average EPs and (iii) spectral distribution of the EPs from single-sweeps. RESULTS Visual inspection revealed no difference between active treatments and placebo (all P > 0.05). Spectral distribution of the averaged potentials showed a decrease in the beta (12-32 Hz) band for fentanyl (P = 0.036), which however did not correlate with pain ratings. Spectral distribution in the single-sweep EPs revealed significant increases in the theta, alpha and beta bands for buprenorphine (all P < 0.05) as well as theta band increase for fentanyl (P = 0.05). For buprenorphine, beta band activity correlated with bone pressure and cutaneous heat pain (both P = 0.04, r = 0.90). CONCLUSION In conclusion single-sweep spectral band analysis increases the information on the response of the brain to opioids and may be used to identify the response to analgesics
L. C. Ehris interaktive læsemodel
No full textArtiklen indeholder en grundlæggende introduktion til den benyttede analysetilgang til læseevalueringsmaterialer for folkeskolens mellem- og overbygning. Her redegøres der nærmere for Linea C. Ehris læsemodel og
den forståelse af læseprocessens mange aspekter og videnformer, hun beskriver i denne model. Der afsluttes med en redegørelse for centrale spørgsmål, som trods analyserne stadig ikke kan besvares uden inddragelse af andre undersøgelsesformer
Tekstlæseprøverne TL 1 med særlig fokus på evalueringen af elevernes genrekendskab og læsestrategi
No full textI det følgende vil tekstlæseprøverne til TL1 blive
behandlet. Efter en kort generel præsentation af
materialet, hvor centrale og grundlæggende teorier
om læsning og læseprocessen vil blive ridset op, vil
vi fokusere på de aspekter inden for læseudviklingen,
som evalueres, herunder materialets tilgang til
og evaluering af elevernes genrekendskab og læsestrategi.
I artiklens sidste del vil vi argumentere for
vigtigheden af et udbygget genrekendskab i folkeskolens
danskundervisning og evaluering
Overtime work, dual job holding and taxation
No full textTraditionally, labour supply data do not include much information on hours and wages in secondary job or overtime work. In this paper, we estimate labour supply models based on survey information on hours and wages in overtime work and second job which is merged to detailed register information on income taxes, deductions, taxable income etc. We also allow for the effect of observed fixed costs in main occupation and unobserved fixed costs in second job, and a ‘stigmatization effect’ from unemployment. The estimated models follow a ‘Hausman-approach’. The results indicate that the labour supply elasticities are highly sensitive to the inclusion of information on overtime work and secondary job and to the handling of fixed costs of work. The estimated elasticities are numerically larger when explicit information on overtime and second job work is taken into account compared to traditional labour supply models without explicit information on overtime pay and second job wages. However, when the model allows for stigmatization effects and unobserved fixed costs of work in second job, the resulting elasticities reduce considerably.Labour supply; Dual job holding; Overtime work; Piecewise linear budget constraints
Overtime Work Dual Job Holding and Taxation
No full textTraditionally, labour supply data do not include much information on hours and wages in
secondary job or overtime work. In this paper, we estimate labour supply models based on
survey information on hours and wages in overtime work and second job which is merged to
detailed register information on income taxes, deductions, taxable income etc. We also allow
for the effect of observed fixed costs in main occupation and unobserved fixed costs in
second job, and a ?stigmatization effect? from unemployment. The estimated models follow a
?Hausman-approach?. The results indicate that the labour supply elasticities are highly
sensitive to the inclusion of information on overtime work and secondary job and to the
handling of fixed costs of work. The estimated elasticities are numerically larger when
explicit information on overtime and second job work is taken into account compared to
traditional labour supply models without explicit information on overtime pay and second job
wages. However, when the model allows for stigmatization effects and unobserved fixed
costs of work in second job, the resulting elasticities reduce considerably
Dislocated dual mobility liner after hip dislocation
No full textIntraprosthetic dislocation (IPD) during closed reduction in primary total hip arthroplasty (THA) with a dual mobility cup (DMC) is a well-known, but rare complication. DMC accounted for 15% of all cups in primary THA in Denmark in 2018, and the prevalence of DMC is increasing. We present a case report of an 83-year-old man, who had an atraumatic hip dislocation five weeks after primary THR. After closed reduction with sedation in the emergency department, IPD occurred. We recommend repositioning of a dislocated THA with DMC to be done by use of fluoroscopy under general anesthaesia with muscle relaxation
Dislocated dual mobility liner after hip dislocation
No full textIntraprosthetic dislocation (IPD) during closed reduction in primary total hip arthroplasty (THA) with a dual mobility cup (DMC) is a well-known, but rare complication. DMC accounted for 15% of all cups in primary THA in Denmark in 2018, and the prevalence of DMC is increasing. We present a case report of an 83-year-old man, who had an atraumatic hip dislocation five weeks after primary THR. After closed reduction with sedation in the emergency department, IPD occurred. We recommend repositioning of a dislocated THA with DMC to be done by use of fluoroscopy under general anesthaesia with muscle relaxation
Ny udsathed i ungdomslivet:11 forskere om den stigende mistrivsel blandt unge
No full textMistrivsel, diagnose-eksplosion, præstationskultur, polarisering og social arv. Mange unge kæmper med en række af udfordringer og det skaber bekymring blandt de voksne. Lærere, vejledere, pædagoger, psykologer og en række andre fagprofessionelle står hver dag i udfordrende situationer med unge, som udviser tegn på mistrivsel. Samtidigt ser vi et væld af begreber, der forsøger at indfange de nye tendenser - men hvad er der på spil? I denne bog kommer 11 forskere med en række forskellige bud på, hvordan vi kan forstå udsathed blandt unge i dag set i lyset af aktuelle samfundsmæssige forandringer. Forskerne kommer derudover med forskellige vinkler på, hvordan man kan arbejde med at fremme de unges livsduelighed. Bogens kapitler bygger på interviews med: Morten Ejrnæs, Hanne Warming, Anders Petersen, Nikolas Rose, Nanna Mik-Meyer, Máirtin Mac an Ghaill, Tracy Shildrick og Robert MacDonald, Christer Hyggen, Kitty te Riele, Jette Kofoed, Line Lerche Mørck. Ny udsathed i ungdomslivet er henvendt til praktikere der arbejder med unge, til studerende, undervisere, politiske beslutningstagere og andre der beskæftiger sig med ungdomsliv og –sociologi. Udgivelsen er et led i Center for Ungdomsforsknings forskningsprojekt: ”Ny udsathed”, som er realiseret vha. en bevilling fra Den Obelske Familiefond.<br/
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