10 research outputs found
Auctions for Split-Award Contracts
The buyer of a homogeneous input employs split-award contracting to divide his input requirements into two contracts that are awarded to different suppliers. The buyer uses a sequential second-price auction to award a larger primary contract and a smaller secondary contract. With a fixed number of suppliers participating in the auctions, we find that the buyer pays a higher expected price than with a sole-source auction. The premium paid to the winner of the secondary contract must also be paid to the winner of the primary contract as an opportunity cost of not winning the secondary contract. With fixed costs of participating in the auction, we identify the conditions under which a secondary contract can increase the number of suppliers and lower the expected price paid by the buyer. An optimal secondary contract can internalize the cost reductions from the new industry capacity and extract the rents of the suppliers. An optimal secondary contract can be particularly beneficial when the number of suppliers is limited by high fixed costs.
Cumulative mortality of Pacific <i>Crassostrea gigas</i> oysters experimentally infected by intramuscular injection with homogenate, seawater, MB-virus conjugates from homogenate and MB-virus conjugates from seawater, bare MBs and sterile water.
Cumulative mortality of Pacific Crassostrea gigas oysters experimentally infected by intramuscular injection with homogenate, seawater, MB-virus conjugates from homogenate and MB-virus conjugates from seawater, bare MBs and sterile water.</p
OsHV-1 DNA detected in the supernatant after the first (W-1), second (W-2) and third (W-3) washing steps and in the MB-virus conjugates from homogenate (MB).
OsHV-1 DNA detected in the supernatant after the first (W-1), second (W-2) and third (W-3) washing steps and in the MB-virus conjugates from homogenate (MB).</p
Rapid capture and detection of ostreid herpesvirus-1 from Pacific oyster <i>Crassostrea gigas</i> and seawater using magnetic beads - Fig 5
Viral DNA quantifications by qPCR in dead/moribund (grey bars) and living (black bars) oysters after intramuscular injection of homogenate (a), seawater (b), MB-virus conjugates from homogenate (c) and MB-virus conjugates from seawater (d). Results (mean ± SD) are expressed as OsHV-1 DNA copies/ng of total DNA. The number above each bar represents the number of oysters analysed.</p
Schematic representation of the protocol for the capture of viable OsHV-1 from the homogenate and the seawater using anionic MBs and subsequent virus detection.
Schematic representation of the protocol for the capture of viable OsHV-1 from the homogenate and the seawater using anionic MBs and subsequent virus detection.</p
Multistate/Multifunctional Systems. A Thermodynamic, Kinetic, and Photochemical Investigation of the 4‘-Dimethylaminoflavylium Compound
The 4‘-dimethylaminoflavylium ion in aqueous solution undergoes an intricate network of chemical
reactions controlled by pH and light excitation. It is shown that nine different forms are involved, including
two species that are not present in previously investigated compounds of the flavylium family. The
thermodynamic and kinetic constants of the equilibria and interconversion processes have been obtained
by pH jump (included stopped-flow) experiments. The photochromic properties exhibited by the trans/cis
chalcone forms have been investigated. The peculiar aspect of 4‘-dimethylaminoflavylium, as compared to
previously investigated compounds of the same family, is a close to planarity structure, as demonstrated
by the X-ray analysis on the parent 4‘-aminoflavylium compound (2.3° torsion angle between the
benzopyrylium and benzene ring). The results obtained show that the flavylium cation is strongly stabilized
by the electron-donor character of the dimethylamino substituent on the benzene ring. The donor−acceptor
interaction makes both the protonation of the amino group and the hydration of the flavylium cation difficult,
with consequences on the tautomerization and cis/trans isomerization reactions. The multistate/multifunctional properties of 4‘-dimethylaminoflavylium have been discussed in the frame of write−lock−read−unlock−erase cycles
Rapid capture and detection of ostreid herpesvirus-1 from Pacific oyster <i>Crassostrea gigas</i> and seawater using magnetic beads - Fig 3
Calibration curves using 4-fold serial dilutions of homogenate (a) and MBs (b, c) while maintaining MB amount (10 μL) and using non-diluted homogenate, respectively. Arrows indicate the same MB/homogenate ratio in (a) and (b). Panel (c) is normalised to 10 μL of MBs.</p
sj-pdf-1-lan-10.1177_00236772231198733 - Supplemental material for Pain management in zebrafish
Supplemental material, sj-pdf-1-lan-10.1177_00236772231198733 for Pain management in zebrafish by Lynne U Sneddon, Paul Schroeder, Ana Roque, Karin Finger-Baier, Angeleen Fleming, Simon Tinman and Bertrand Collet in Laboratory Animals</p
Relative expression of the 3 viral gene transcripts (ORF4, ORAF16, ORF42) in moribund and living oysters.
Ct results (mean ± SD) are normalised to EF1. Lower Ct values correspond to earlier detection (higher expression levels) of each transcript. A total of 12 moribund oysters and 12 living oysters were analysed.</p
Coordination Properties of a Polyamine Cryptand with Two Different Binding Moieties. A Case of a pH-Modulated Antenna Device Based on a New Eu(III) Cryptate Complex
Protonation and alkali- and alkaline-earth-metal coordination by the dipyridine-containing cryptand L have been
studied by means of potentiometric and spectroscopic (UV−vis, 1H NMR) measurements in aqueous solutions.
This ligand is constituted by an aliphatic polyamine chain and a coordinating cleft, delimited by two dipyridine
units, where the metal ion is lodged. The resulting complexes are characterized by an unusually high stability.
The polyamine chain is not involved, or weakly involved, in metal coordination, and facile protonation can occur
on the nitrogen atoms of this moiety. Similar coordination features are found in the Eu(III) complex. A fluorescence
emission study reveals that the Eu(III) cryptate shows the characteristic visible emission of the metal, due to the
intramolecular energy transfer to the metal ion mainly from the lower energy triplet state of the cryptand. On the
other hand, the emission intensity is modulated by pH, giving a maximum at neutral pH and decreasing at both
acidic and alkaline pH values
